Non-Hydroxamate Zinc-Binding Groups as Warheads for Histone Deacetylases von Frühauf, Anton, Meyer-Almes, Franz-Josef

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The catalytic domain of free or ligand bound histone deacetylase 4 occurs in solution predominantly in closed conformation von Schweipert, Markus, Nehls, Thomas, Frühauf, Anton, Debarnot, Cecilé, Kumar, Adarsh, Knapp, Stefan, Lermyte, Frederik, Meyer‐Almes, Franz‐Josef

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Design and synthesis of peptides as stabilizers of histone deacetylase 4 von Lill, Annika, Schweipert, Markus, Nehls, Thomas, Wurster, Eva, Lermyte, Frederik, Meyer‐Almes, Franz‐Josef, Schmitz, Katja

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Significance of Five-Membered Heterocycles in Human Histone Deacetylase Inhibitors von Frühauf, Anton, Behringer, Martin, Meyer-Almes, Franz-Josef

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Enhanced Protein Degradation by Branched Ubiquitin Chains von Meyer, Hermann-Josef, Rape, Michael

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Switching the Switch: Ligand Induced Disulfide Formation in HDAC8 von Jänsch, Niklas, Sugiarto, Wisely Oki, Muth, Marius, Kopranovic, Aleksandra, Desczyk, Charlotte, Ballweg, Matthias, Kirschhöfer, Frank, Brenner‐Weiss, Gerald, Meyer‐Almes, Franz‐Josef

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Synthesis and Biological Evaluation of Pyrazoline and Pyrrolidine‐2,5‐dione Hybrids as Potential Antitumor Agents von Tilekar, Kalpana, Upadhyay, Neha, Meyer‐Almes, Franz‐Josef, Loiodice, Fulvio, Anisimova, Natalia Y., Spirina, Tatiana S., Sokolova, Darina V., Smirnova, Galina B., Choe, Jun‐yong, Pokrovsky, Vadim S., Lavecchia, Antonio, S Ramaa, C

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Assessment of Tractable Cysteines for Covalent Targeting by Screening Covalent Fragments von Petri, László, Ábrányi‐Balogh, Péter, Tímea, Imre, Pálfy, Gyula, Perczel, András, Knez, Damijan, Hrast, Martina, Gobec, Martina, Sosič, Izidor, Nyíri, Kinga, Vértessy, Beáta G., Jänsch, Niklas, Desczyk, Charlotte, Meyer‐Almes, Franz‐Josef, Ogris, Iza, Golič Grdadolnik, Simona, Iacovino, Luca Giacinto, Binda, Claudia, Gobec, Stanislav, Keserű, György M.

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Potent and Selective Non-hydroxamate Histone Deacetylase 8 Inhibitors von Kleinschek, Alexander, Meyners, Christian, Digiorgio, Eros, Brancolini, Claudio, Meyer-Almes, Franz-Josef

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Design, Synthesis, and Biological Evaluation of Novel Quinazolin-4(3H)-One-Based Histone Deacetylase 6 (HDAC6) Inhibitors for Anticancer Activity von Khetmalis, Yogesh Mahadu, Fathima, Ashna, Schweipert, Markus, Debarnot, Cécile, Bandaru, Naga Venkata Madhusudhan Rao, Murugesan, Sankaranarayanan, Jamma, Trinath, Meyer-Almes, Franz-Josef, Sekhar, Kondapalli Venkata Gowri Chandra

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High throughput screening identifies novel, cell cycle‐arresting small molecule enhancers of transient protein expression von Meyer, Hermann‐Josef, Turincio, Rebecca, Ng, Shirley, Li, Juan, Wilson, Blair, Chan, Pamela, Zak, Mark, Reilly, Dorothea, Beresini, Maureen H., Wong, Athena W.

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Processive ubiquitin chain formation by the anaphase-promoting complex von Meyer, Hermann-Josef, Rape, Michael

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3‐Chloro‐5‐Substituted‐1,2,4‐Thiadiazoles (TDZs) as Selective and Efficient Protein Thiol Modifiers von Jänsch, Niklas, Frühauf, Anton, Schweipert, Markus, Debarnot, Cécile, Erhardt, Miriam, Brenner‐Weiss, Gerald, Kirschhöfer, Frank, Jasionis, Tomas, Čapkauskaitė, Edita, Zubrienė, Asta, Matulis, Daumantas, Meyer‐Almes, Franz‐Josef

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Synthesis and HDAC inhibitory activity of pyrimidine-based hydroxamic acids von Jakubkiene, Virginija, Valiulis, Gabrielius Ernis, Schweipert, Markus, Zubriene, Asta, Matulis, Daumantas, Meyer-Almes, Franz-Josef, Tumkevicius, Sigitas

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The enzyme activity of histone deacetylase 8 is modulated by a redox-switch von Jänsch, Niklas, Meyners, Christian, Muth, Marius, Kopranovic, Aleksandra, Witt, Olaf, Oehme, Ina, Meyer-Almes, Franz-Josef

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Discrimination between conformational selection and induced fit protein–ligand binding using Integrated Global Fit analysis von Meyer-Almes, Franz-Josef

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Continuous enzyme activity assay for high-throughput classification of histone deacetylase 8 inhibitors von Schweipert, Markus, Amurthavasan, Anuja, Meyer-Almes, Franz-Josef

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Rapid Determination of Kinetic Constants for Slow-Binding Inhibitors and Inactivators of Human Histone Deacetylase 8 von Kopranovic, Aleksandra, Meyer-Almes, Franz-Josef

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Defining the Mechanism of Action and Enzymatic Selectivity of Psammaplin A against Its Epigenetic Targets von Baud, Matthias G. J, Leiser, Thomas, Haus, Patricia, Samlal, Sharon, Wong, Ai Ching, Wood, Robert J, Petrucci, Vanessa, Gunaratnam, Mekala, Hughes, Siobhan M, Buluwela, Lakjaya, Turlais, Fabrice, Neidle, Stephen, Meyer-Almes, Franz-Josef, White, Andrew J. P, Fuchter, Matthew J

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Identification of a novel miRNA that increases transient protein expression in combination with valproic acid von Meyer, Hermann‐Josef, Reilly, Dorothea, Martin, Scott E., Wong, Athena W.

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