GBT440 increases haemoglobin oxygen affinity, reduces sickling and prolongs RBC half‐life in a murine model of sickle cell disease von Oksenberg, Donna, Dufu, Kobina, Patel, Mira P., Chuang, Chihyuan, Li, Zhe, Xu, Qing, Silva‐Garcia, Abel, Zhou, Chengjing, Hutchaleelaha, Athiwat, Patskovska, Larysa, Patskovsky, Yury, Almo, Steven C., Sinha, Uma, Metcalf, Brian W., Archer, David R.

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GBT 440 increases haemoglobin oxygen affinity, reduces sickling and prolongs RBC half‐life in a murine model of sickle cell disease von Oksenberg, Donna, Dufu, Kobina, Patel, Mira P., Chuang, Chihyuan, Li, Zhe, Xu, Qing, Silva‐Garcia, Abel, Zhou, Chengjing, Hutchaleelaha, Athiwat, Patskovska, Larysa, Patskovsky, Yury, Almo, Steven C., Sinha, Uma, Metcalf, Brian W., Archer, David R.

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An Orally Bioavailable HIV-1 Protease Inhibitor Containing an Imidazole-Derived Peptide Bond Replacement: Crystallographic and Pharmacokinetic Analysis von Abdel-Meguid, Sherin S, Metcalf, Brian W, Carr, Thomas J, Demarsh, Peter, DesJarlais, Renee L, Fisher, Seth, Green, David W, Ivanoff, Lucinda, Lambert, Dennis M

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cis-4-Carboxy-6-(mercaptomethyl)-3,4,5,6-tetrahydropyrimidin-2(1H)-one, a potent inhibitor of mammalian dihydroorotase von Adams, Jerry L, Meek, Thomas D, Mong, Shau Ming, Johnson, Randall K, Metcalf, Brian W

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Inhibition of HIV-1 protease in infected T-lymphocytes by synthetic peptide analogues von Meek, Thomas D, Lambert, Dennis M, Dreyer, Geoffrey B, Carr, Thomas J, Tomaszek, Thaddeus A, Moore, Michael L, Strickler, James E, Debouck, Christine, Hyland, Lawrence J, Matthews, Thomas J, Metcalf, Brian W, Petteway, Stephen R

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alpha.-Ethynyl and .alpha.-vinyl analogs of ornithine as enzyme-activated inhibitors of mammalian ornithine decarboxylase von Danzin, Charles, Casara, Patrick, Claverie, Nicole, Metcalf, Brian W

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Inhibition of rat liver steroid 5.alpha.-reductase by 3-androstene-3-carboxylic acids: mechanism of enzyme-inhibitor interaction von Levy, Mark A, Brandt, Martin, Heys, J. Richard, Holt, Dennis A, Metcalf, Brian W

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Inhibition of steroid 5.alpha.-reductase by unsaturated 3-carboxy steroids von Holt, Dennis A, Levy, Mark A, Oh, Hye Ja, Erb, Jill M, Heaslip, Julie I, Brandt, Martin, Lan-Hargest, Hsuan Yin, Metcalf, Brian W

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Synthesis and antiviral activity of a novel class of HIV-1 protease inhibitors containing a heterocyclic P1′-P2′ amide bond isostere von Thompson, Scott K., Eppley, Alecia M., Frazee, James S., Darcy, Michael G., Lum, Robert T., Tomaszek, Thaddeus A., Ivanoff, Lucinda A., Morris, Jane F., Sternberg, Edmund J., Lambert, Dennis M., Fernandez, Annabellee V., Petteway, Stephen R., Meek, Thomas D, Metcalf, Brian W., Gleason, John G.

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Proteolysis of an active site peptide of lactate dehydrogenase by human immunodeficiency virus type 1 protease von Tomaszek, Thaddeus A, Moore, Michael L, Strickler, James E, Sanchez, Robert L, Dixon, J. Scott, Metcalf, Brian W, Hassell, Anne, Dreyer, Geoffrey B, Brooks, Isobel

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COMPOUNDS AND USES THEREOF FOR THE MODULATION OF HEMOGLOBIN von CHIHYUAN CHUANG, BRIAN W. METCALF

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A stereospecific total synthesis of racemic 11.alpha.-hydroxyprogesterone via a biomimetic polyene cyclization von Johnson, William S, Escher, Sina, Metcalf, Brian W

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The synthesis of fluorinated aminophosphonic acid inhibitors of alanine racemase von Flynn, Gary A., Beight, Douglas W., Bohme, Ekkehard H.W., Metcalf, Brian W.

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Slow binding inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A reductase von Louis-Flamberg, Pearl, Peishoff, Catherine E, Bryan, Deborah L, Leber, Jack, Elliott, John D, Metcalf, Brian W, Mayer, Ruth J

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Pyrimidinones as PI3K inhibitors von Li, Yun-Long, Metcalf, Brian W, Combs, Andrew P

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Human Immunodeficiency Virus Protease Expressed in Escherichia coli Exhibits Autoprocessing and Specific Maturation of the Gag Precursor von Debouck, Christine, Gorniak, Joselina G., Strickler, James E., Meek, Thomas D., Metcalf, Brian W., Rosenberg, Martin

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SUBSTITUTED HETEROARYL ALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION von Chuang, Chihyuan, Metcalf, Brian W

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Inhibition of Human Immunodeficiency Virus 1 Protease in vitro: Rational Design of Substrate Analogue Inhibitors von Dreyer, Geoffrey B., Metcalf, Brian W., Tomaszek, Thaddeus A., Carr, Thomas J., Chandler, Arthur C., Hyland, Lawrence, Fakhoury, Stephen A., Magaard, Victoria W., Moore, Michael L., Strickler, James E., Debouck, Christine, Meek, Thomas D.

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Cleavage of tert-butyldimethylsilyl ethers by tetrafluoroborate salts von Metcalf, Brian W., Burkhart, Joseph P., Jund, Karin

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Compounds and uses thereof for the modulation of hemoglobin von Chuang, Chihyuan, Metcalf, Brian W

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