Pharmacogenetics of Long-Term Responses to Antiretroviral Regimens Containing Efavirenz and/or Nelfinavir: An Adult AIDS Clinical Trials Group Study von Haas, David W., Smeaton, Laura M., Shafer, Robert W., Robbins, Gregory K., Morse, Gene D., Labbé, Line, Wilkinson, Grant R., Clifford, David B., D’Aquila, Richard T., De Gruttola, Victor, Pollard, Richard B., Merigan, Thomas C., Hirsch, Martin S., George, Alfred L., Donahue, John P., Kim, Richard B.

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Role of Physician-Scientists in the Control of Human Immunodeficiency Virus von Merigan, Thomas C

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“Wide-Open” 1.3 Å Structure of a Multidrug-Resistant HIV-1 Protease as a Drug Target von Martin, Philip, Vickrey, John F., Proteasa, Gheorghe, Jimenez, Yurytzy L., Wawrzak, Zdzislaw, Winters, Mark A., Merigan, Thomas C., Kovari, Ladislau C.

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In vitro HIV-1 evolution in response to triple reverse transcriptase inhibitors & in silico phenotypic analysis von Rath, Barbara A, Yousef, Kaveh Pouran, Katzenstein, David K, Shafer, Robert W, Schütte, Christof, von Kleist, Max, Merigan, Thomas C

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Multilocus genetic interactions and response to efavirenz-containing regimens: an Adult AIDS Clinical Trials Group study von Motsinger, Alison A, Ritchie, Marylyn D, Shafer, Robert W, Robbins, Gregory K, Morse, Gene D, Labbe´, Line, Wilkinson, Grant R, Clifford, David B, DʼAquila, Richard T, Johnson, Victoria A, Pollard, Richard B, Merigan, Thomas C, Hirsch, Martin S, Donahue, John P, Kim, Richard B, Haas, David W

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Crystal Structures of a Multidrug-Resistant Human Immunodeficiency Virus Type 1 Protease Reveal an Expanded Active-Site Cavity von LOGSDON, Bradley C, VICKREY, John F, MARTIN, Philip, PROTEASA, Gheorghe, KOEPKE, Jay I, TERLECKY, Stanley R, WAWRZAK, Zdzislaw, WINTERS, Mark A, MERIGAN, Thomas C, KOVARI, Ladislau C

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Phase 2 gene therapy trial of an anti-HIV ribozyme in autologous CD34 + cells von Mitsuyasu, Ronald T, Merigan, Thomas C, Carr, Andrew, Zack, Jerome A, Winters, Mark A, Workman, Cassy, Bloch, Mark, Lalezari, Jacob, Becker, Stephen, Thornton, Lorna, Akil, Bisher, Khanlou, Homayoon, Finlayson, Robert, McFarlane, Robert, Smith, Don E, Garsia, Roger, Ma, David, Law, Matthew, Murray, John M, von Kalle, Christof, Ely, Julie A, Patino, Sharon M, Knop, Alison E, Wong, Philip, Todd, Alison V, Haughton, Margaret, Fuery, Caroline, Macpherson, Janet L, Symonds, Geoff P, Evans, Louise A, Pond, Susan M, Cooper, David A

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Effect of Baseline- and Treatment-Related Factors on Immunologic Recovery After Initiation of Antiretroviral Therapy in HIV-1-Positive Subjects: Results From ACTG 384 von Gandhi, Rajesh T, Spritzler, John, Chan, Ellen, Asmuth, David M, Rodriguez, Benigno, Merigan, Thomas C, Hirsch, Martin S, Shafer, Robert W, Robbins, Gregory K, Pollard, Richard B

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Variants Other than Aspartic Acid at Codon 69 of the Human Immunodeficiency Virus Type 1 Reverse Transcriptase Gene Affect Susceptibility to Nucleoside Analogs von WINTERS, Mark A, MERIGAN, Thomas C

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Antiviral Activity of Lamivudine in Salvage Therapy for Multidrug-Resistant HIV-1 Infection von Campbell, Thomas B., Shulman, Nancy S., Johnson, Steven C., Zolopa, Andrew R., Young, Russell K., Bushman, Lane, Fletcher, Courtney V., Lanier, E. Randall, Merigan, Thomas C., Kuritzkes, Daniel R.

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High Degree of Interlaboratory Reproducibility of Human Immunodeficiency Virus Type 1 Protease and Reverse Transcriptase Sequencing of Plasma Samples from Heavily Treated Patients von SHAFER, Robert W, HERTOGS, Kurt, ZOLOPA, Andrew R, WARFORD, Ann, BLOOR, Stuart, BETTS, Bradley J, MERIGAN, Thomas C, HARRIGAN, Richard, LARDER, Brendon A

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Association of a Novel Human Immunodeficiency Virus Type 1 Protease Substrate Cleft Mutation, L23I, with Protease Inhibitor Therapy and In Vitro Drug Resistance von JOHNSTON, Elizabeth, WINTERS, Mark A, RHEE, Soo-Yon, MERIGAN, Thomas C, SCHIFFER, Celia A, SHAFER, Robert W

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A Trial Comparing Nucleoside Monotherapy with Combination Therapy in HIV-Infected Adults with CD4 Cell Counts from 200 to 500 per Cubic Millimeter von Hammer, Scott M, Katzenstein, David A, Hughes, Michael D, Gundacker, Holly, Schooley, Robert T, Haubrich, Richard H, Henry, W. Keith, Lederman, Michael M, Phair, John P, Niu, Manette, Hirsch, Martin S, Merigan, Thomas C

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Granulocyte-Macrophage Colony-Stimulating Factor Induces Modest Increases in Plasma Human Immunodeficiency Virus (HIV) Type 1 RNA Levels and CD4+ Lymphocyte Counts in Patients with... von Jacobson, Jeffrey M., Lederman, Michael M., Spritzler, John, Valdez, Hernan, Tebas, Pablo, Skowron, Gail, Wang, Rui, Jackson, J. Brooks, Fox, Lawrence, Landay, Alan, Gilbert, Mark J., O’Neil, Dorothy, Bancroft, Lynne, Al-Harthi, Lena, Jacobson, Mark A., Merigan, Thomas C.

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Hydroxyurea Enhances the Activities of Didanosine, 9-[2-(Phosphonylmethoxy)ethyl]adenine, and 9-[2-(Phosphonylmethoxy)propyl]adenine against Drug-Susceptible and Drug-Resistant Hum... von Palmer, S, Shafer, R W, Merigan, T C

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Extensive polymorphisms observed in HIV-1 clade B protease gene using high-density oligonucleotide arrays von Kozal, Michael J, Shah, Nila, Shen, Naiping, Yang, Robert, Fucini, Raymond, Merigan, Thomas C, Richman, Douglas D, Morris, Don, Hubbell, Earl, Chee, Mark, Gingeras, Thomas R

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Treatment of Human Immunodeficiency Virus Infection with Saquinavir, Zidovudine, and Zalcitabine von Collier, Ann C, Coombs, Robert W, Schoenfeld, David A, Bassett, Roland L, Timpone, Joseph, Baruch, Alice, Jones, Michelle, Facey, Karen, Whitacre, Caroline, McAuliffe, Vincent J, Friedman, Harvey M, Merigan, Thomas C, Reichman, Richard C, Hooper, Carol, Corey, Lawrence

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Frequency of Class I HLA-Restricted Anti-HIV CD8+ T Cells in Individuals Receiving Highly Active Antiretroviral Therapy (HAART) von Gray, Clive M, Lawrence, Jody, Schapiro, Jonathan M, Altman, John D, Winters, Mark A, Crompton, Meg, Loi, Muoi, Kundu, Smriti K, Davis, Mark M, Merigan, Thomas C

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Insertions in the human immunodeficiency virus type 1 protease and reverse transcriptase genes : Clinical impact and molecular mechanisms von WINTERS, Mark A, MERIGAN, Thomas C

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Pharmacokinetics of Nelfinavir and Efavirenz in Antiretroviral-Naïve, Human Immunodeficiency Virus-Infected Subjects when Administered Alone or in Combination with Nucleoside Analo... von Smith, Patrick F, Robbins, Gregory K, Shafer, Robert W, Wu, Hulin, Yu, Song, Hirsch, Martin S, Merigan, Thomas C, Park, Jeong-Gun, Forrest, Alan, Fischl, Margaret A, Morse, Gene D

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