Timing of Antiviral Treatment Initiation is Critical to Reduce SARS‐CoV‐2 Viral Load von Gonçalves, Antonio, Bertrand, Julie, Ke, Ruian, Comets, Emmanuelle, Lamballerie, Xavier, Malvy, Denis, Pizzorno, Andrés, Terrier, Olivier, Rosa Calatrava, Manuel, Mentré, France, Smith, Patrick, Perelson, Alan S., Guedj, Jérémie

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Robust designs accounting for model uncertainty in longitudinal studies with binary outcomes von Seurat, Jérémy, Nguyen, Thu Thuy, Mentré, France

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Microbiota-based markers predictive of development of Clostridioides difficile infection von Berkell, Matilda, Mysara, Mohamed, Xavier, Basil Britto, van Werkhoven, Cornelis H., Monsieurs, Pieter, Lammens, Christine, Ducher, Annie, Vehreschild, Maria J. G. T., Goossens, Herman, de Gunzburg, Jean, Bonten, Marc J. M., Malhotra-Kumar, Surbhi

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Distributive randomization: a pragmatic fractional factorial design to screen or evaluate multiple simultaneous interventions in a clinical trial von Haviari, Skerdi, Mentré, France

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Incidence and predictive biomarkers of Clostridioides difficile infection in hospitalized patients receiving broad-spectrum antibiotics von van Werkhoven, Cornelis H., Ducher, Annie, Berkell, Matilda, Mysara, Mohamed, Lammens, Christine, Torre-Cisneros, Julian, Rodríguez-Baño, Jesús, Herghea, Delia, Cornely, Oliver A., Biehl, Lena M., Bernard, Louis, Dominguez-Luzon, M. Angeles, Maraki, Sofia, Barraud, Olivier, Nica, Maria, Jazmati, Nathalie, Sablier-Gallis, Frederique, de Gunzburg, Jean, Mentré, France, Malhotra-Kumar, Surbhi, Bonten, Marc J. M., Vehreschild, Maria J. G. T.

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Assessment of the Drug Susceptibility of Plasmodium falciparum Clinical Isolates from Africa by Using a Plasmodium Lactate Dehydrogenase Immunodetection Assay and an Inhibitory Max... von KADDOURI, Halima, NAKACHE, Serge, HOUZE, Sandrine, MENTRE, France, LE BRAS, Jacques

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Preclinical in vivo assessment of the activity of AZD7442 anti-SARS-CoV-2 monoclonal antibodies against Omicron sublineages von Driouich, Jean-Sélim, Cochin, Maxime, Lingas, Guillaume, Luciani, Léa, Baronti, Cécile, Bernadin, Ornéllie, Gilles, Magali, Villarroel, Paola Mariela Saba, Moureau, Grégory, Petit, Paul-Rémi, Dupont, Axelle, Izopet, Jacques, Kamar, Nassim, Autran, Brigitte, Paintaud, Gilles, Caillard, Sophie, le Bourgeois, Amandine, Richez, Christophe, Couzi, Lionel, Xhaard, Aliénor, Marjanovic, Zora, Avouac, Jerome, Jacquet, Caroline, Anglicheau, Dany, Cheminant, Morgane, Nguyen, Stéphanie, Terrier, Benjamin, Gottenberg, Jacques Eric, Besson, Caroline, Letrou, Sophie, Tine, Josephine, Basilua, Joe Miantezila, Angoulvant, Denis, Tardivon, Coralie, Blancho, Gilles, Martin-Blondel, Guillaume, Yazdanpanah, Yazdan, Mentré, France, Lévy, Vincent, Touret, Franck, Guedj, Jérémie, de Lamballerie, Xavier, Nougairède, Antoine

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Antiviral efficacy of favipiravir against Ebola virus: A translational study in cynomolgus macaques von Guedj, Jérémie, Piorkowski, Géraldine, Jacquot, Frédéric, Madelain, Vincent, Nguyen, Thi Huyen Tram, Rodallec, Anne, Gunther, Stephan, Carbonnelle, Caroline, Mentré, France, Raoul, Hervé, de Lamballerie, Xavier

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Ebola Virus Infection: Review of the Pharmacokinetic and Pharmacodynamic Properties of Drugs Considered for Testing in Human Efficacy Trials von Madelain, Vincent, Nguyen, Thi Huyen Tram, Olivo, Anaelle, de Lamballerie, Xavier, Guedj, Jérémie, Taburet, Anne-Marie, Mentré, France

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Developing Tools to Evaluate Non-linear Mixed Effect Models: 20 Years on the npde Adventure von Comets, Emmanuelle, Mentré, France

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Protection of the Human Gut Microbiome From Antibiotics von de Gunzburg, Jean, Ghozlane, Amine, Ducher, Annie, Le Chatelier, Emmanuelle, Duval, Xavier, Ruppé, Etienne, Armand-Lefevre, Laurence, Sablier-Gallis, Frédérique, Burdet, Charles, Alavoine, Loubna, Chachaty, Elisabeth, Augustin, Violaine, Varastet, Marina, Levenez, Florence, Kennedy, Sean, Pons, Nicolas, Mentré, France, Andremont, Antoine

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Computing normalised prediction distribution errors to evaluate nonlinear mixed-effect models: The npde add-on package for R von Comets, Emmanuelle, Brendel, Karl, Mentré, France

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Ebola viral dynamics in nonhuman primates provides insights into virus immuno-pathogenesis and antiviral strategies von Madelain, Vincent, Baize, Sylvain, Jacquot, Frédéric, Reynard, Stéphanie, Fizet, Alexandra, Barron, Stephane, Solas, Caroline, Lacarelle, Bruno, Carbonnelle, Caroline, Mentré, France, Raoul, Hervé, de Lamballerie, Xavier, Guedj, Jérémie

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Phase II Study of Cetuximab As First-Line Single-Drug Therapy in Patients With Unresectable Squamous Cell Carcinoma of the Skin von MAUBEC, Eve, PETROW, Peter, BASSET-SEGUIN, Nicole, SAEZ, Pierre, DUVAL-MODESTE, Anne-Bénédicte, ADAMSKI, Henri, MANSARD, Sandrine, GRANGE, Florent, DOMPMARTIN, Anne, FAIVRE, Sandrine, MENTRE, France, AVRIL, Marie-Françoise, SCHEER-SENYARICH, Isabelle, DUVILLARD, Pierre, LACROIX, Ludovic, GELLY, Julien, CERTAIN, Agnès, DUVAL, Xavier, CRICKX, Béatrice, BUFFARD, Valérie

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Welcome to the statistics and pharmacometrics themed issue von French, Jonathan, Mentré, France

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CPT: Pharmacometrics & Systems Pharmacology 2.0 von Mentré, France

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Favipiravir pharmacokinetics in Ebola-Infected patients of the JIKI trial reveals concentrations lower than targeted von Nguyen, Thi Huyen Tram, Guedj, Jérémie, Anglaret, Xavier, Laouénan, Cédric, Madelain, Vincent, Taburet, Anne-Marie, Baize, Sylvain, Sissoko, Daouda, Pastorino, Boris, Rodallec, Anne, Piorkowski, Géraldine, Carazo, Sara, Conde, Mamoudou N, Gala, Jean-Luc, Bore, Joseph Akoi, Carbonnelle, Caroline, Jacquot, Frédéric, Raoul, Hervé, Malvy, Denis, de Lamballerie, Xavier, Mentré, France

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MOSAIC: A cohort study of human mpox virus disease von Pesonel, Elise, Hoffmann, Isabelle, Guiraud, Laetitia, Bourner, Josephine, Diallo, Alpha, Dunning, Jake, Horby, Peter, Kali, Sabrina, Laouénan, Cédric, Mentré, France, Merson, Laura, Molino, Diana, Palich, Romain, Rojek, Amanda, Tacconelli, Evelina, Tardivon, Coralie, Yazdanpanah, Yazdan, Calmy, Alexandra, Lescure, F-Xavier, Olliaro, Piero

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The number of cases, mortality and treatments of viral hemorrhagic fevers: A systematic review von Belhadi, Drifa, El Baied, Majda, Mulier, Guillaume, Malvy, Denis, Mentré, France, Laouénan, Cédric

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Evaluation by simulation of clinical trial designs for evaluation of treatment during a viral haemorrhagic fever outbreak von Manchon, Pauline, Belhadi, Drifa, Mentre, France, Laouenan, Cedric

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