Direct control of CAR T cells through small molecule-regulated antibodies von Park, Spencer, Pascua, Edward, Lindquist, Kevin C., Kimberlin, Christopher, Deng, Xiaodi, Mak, Yvonne S. L., Melton, Zea, Johnson, Theodore O., Lin, Regina, Boldajipour, Bijan, Abraham, Robert T., Pons, Jaume, Sasu, Barbra Johnson, Van Blarcom, Thomas J., Chaparro-Riggers, Javier

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Dual checkpoint blockade of CD47 and PD-L1 using an affinity-tuned bispecific antibody maximizes antitumor immunity von Chen, Shih-Hsun, Dominik, Pawel K, Stanfield, Jessica, Ding, Sheng, Yang, Wenjing, Kurd, Nadia, Llewellyn, Ryan, Heyen, Jonathan, Wang, Carole, Melton, Zea, Van Blarcom, Thomas, Lindquist, Kevin C, Chaparro-Riggers, Javier, Salek-Ardakani, Shahram

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267 Dual checkpoint blockade of CD47 and PD-L1 using an affinity-tuned bispecific antibody maximizes anti-tumor immunity and improves therapeutic window von Chen, Shih-Hsun, Dominik, Pawel, Stanfield, Jessica, Ding, Sheng, Yang, Wenjing, Kurd, Nadia, Llewellyn, Ryan, Heyen, Jonathan, Wang, Carole, Melton, Zea, Lindquist, Kevin, Blarcom, Thomas Van, Chaparro-riggers, Javier, Salek-Ardakani, Shahram

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Preclinical Development and Evaluation of Allogeneic CAR T Cells Targeting CD70 for the Treatment of Renal Cell Carcinoma von Panowski, Siler H, Srinivasan, Surabhi, Tan, Nguyen, Tacheva-Grigorova, Silvia K, Smith, Bryan, Mak, Yvonne S L, Ning, Hongxiu, Villanueva, Jonathan, Wijewarnasuriya, Dinali, Lang, Shanshan, Melton, Zea, Ghosh, Adit, Dusseaux, Mathilde, Galetto, Roman, Heyen, Jonathan R, Sai, Tao, Van Blarcom, Thomas, Chaparro-Riggers, Javier, Sasu, Barbra J

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Abstract 6599: Screening and characterization of AlloCAR T targeting DLL3 for the treatment of small cell lung cancer von Zhang, Yi, Tacheva-Grigorova, Silvia, Melton, Zea, Smith, Bryan, Sai, Tao, Van Blarcom, Tom, Amado, Rafael, Sasu, Barbra, Panowski, Siler

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Allogeneic CAR T Cells Targeting DLL3 Are Efficacious and Safe in Preclinical Models of Small Cell Lung Cancer von Zhang, Yi, Tacheva-Grigorova, Silvia K, Sutton, Janette, Melton, Zea, Mak, Yvonne S L, Lay, Cecilia, Smith, Bryan A, Sai, Tao, Van Blarcom, Thomas, Sasu, Barbra J, Panowski, Siler H

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Precise and Efficient Antibody Epitope Determination through Library Design, Yeast Display and Next-Generation Sequencing von Van Blarcom, Thomas, Rossi, Andrea, Foletti, Davide, Sundar, Purnima, Pitts, Steven, Bee, Christine, Melton Witt, Jody, Melton, Zea, Hasa-Moreno, Adela, Shaughnessy, Lee, Telman, Dilduz, Zhao, Lora, Cheung, Wai Ling, Berka, Jan, Zhai, Wenwu, Strop, Pavel, Chaparro-Riggers, Javier, Shelton, David L., Pons, Jaume, Rajpal, Arvind

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Abstract 3239: SMIC CAR T cells: CAR T with temporally-controlled, programmable cytokine signaling outputs von Lin, Regina, Nager, Andrew, Park, Spencer, Sutton, Janette, Melton, Zea, Zhang, Yi, Boldajipour, Bijan, Van Blarcom, Tom, Panowski, Siler, Chaparro-Riggers, Javier, Sasu, Barbra

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Preclinical Evaluation of ALLO-819, an Allogeneic CAR T Cell Therapy Targeting FLT3 for the Treatment of Acute Myeloid Leukemia von Sommer, Cesar, Cheng, Hsin-Yuan, Yeung, Yik Andy, Nguyen, Duy, Sutton, Janette, Melton, Zea, Valton, Julien, Poulsen, Kris, Djuretic, Ivana, Van Blarcom, Thomas, Chaparro-Riggers, Javier, Sasu, Barbra

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Design and Validation of Inducible TurboCARs with Tunable Induction and Combinatorial Cytokine Signaling von Lin, Regina J., Nager, Andrew R., Park, Spencer, Sutton, Janette, Lay, Cecilia, Melton, Zea, Zhang, Yi, Boldajipour, Bijan, Blarcom, Thomas J. Van, Panowski, Siler H., Sasu, Barbra J., Chaparro-Riggers, Javier

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Productive common light chain libraries yield diverse panels of high affinity bispecific antibodies von Van Blarcom, Thomas, Lindquist, Kevin, Melton, Zea, Cheung, Wai Ling, Wagstrom, Chris, McDonough, Dan, Valle Oseguera, Cendy, Ding, Sheng, Rossi, Andrea, Potluri, Shobha, Sundar, Purnima, Pitts, Steven, Sirota, Marina, Galindo Casas, Meri, Yan, Yu, Jones, Jeffrey, Roe-Zurz, Zygy, Srivatsa Srinivasan, Surabhi, Zhai, Wenwu, Pons, Jaume, Rajpal, Arvind, Chaparro-Riggers, Javier

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Epitope Mapping Using Yeast Display and Next Generation Sequencing von Van Blarcom, Thomas, Rossi, Andrea, Foletti, Davide, Sundar, Purnima, Pitts, Steven, Melton, Zea, Telman, Dilduz, Zhao, Lora, Cheung, Wai Ling, Berka, Jan, Zhai, Wenwu, Strop, Pavel, Pons, Jaume, Rajpal, Arvind, Chaparro-Riggers, Javier

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Abstract LB210: Preclinical development and evaluation of allogeneic CAR T cells targeting CD70 for the treatment of renal cell carcinoma von Panowski, Siler, Srinivasan, Surabhi, Tan, Nguyen, Tacheva-Grigorova, Silvia, Smith, Bryan, Mak, Yvonne, Ning, Hongxiu, Villanueva, Jonathan, Wijewarnasuriya, Dinali, Lang, Shanshan, Melton, Zea, Ghosh, Adit, Dusseaux, Mathilde, Galetto, Roman, Heyen, Jonathan, Sai, Tao, Van Blarcom, Thomas, Chaparro-Riggers, Javier, Sasu, Barbra

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B-CELL MATURATION ANTIGEN (BCMA) ANTI-IDIOTYPIC ANTIBODIES von SAI, Tao, MELTON, Zea, VAN BLARCOM, Thomas John

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B-CELL MATURATION ANTIGEN (BCMA) ANTI-IDIOTYPIC ANTIBODIES von Melton, Zea, Van Blarcom, Thomas John, Sai, Tao

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B-CELL MATURATION ANTIGEN (BCMA) ANTI-IDIOTYPIC ANTIBODIES von SAI, Tao, MELTON, Zea, VAN BLARCOM, Thomas John

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CD70 ANTI-IDIOTYPE ANTIBODIES von PANOWSKI, Siler, SRIVATSA SRINIVASAN, Surabhi, MELTON, Zea, VAN BLARCOM, Thomas John

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CD70 ANTI-IDIOTYPE ANTIBODIES von PANOWSKI, Siler, SRIVATSA SRINIVASAN, Surabhi, MELTON, Zea, VAN BLARCOM, Thomas John

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Productive common light chain libraries yield diverse panels of high affinity bispecific antibodies von Van Blarcom, Thomas, Lindquist, Kevin, Melton, Zea, Cheung, Wai Ling, Wagstrom, Chris, McDonough, Dan, Valle Oseguera, Cendy, Ding, Sheng, Rossi, Andrea, Potluri, Shobha, Sundar, Purnima, Pitts, Steven, Sirota, Marina, Galindo Casas, Meri, Yan, Yu, Jones, Jeffrey, Roe-Zurz, Zygy, Srivatsa Srinivasan, Surabhi, Zhai, Wenwu, Pons, Jaume, Rajpal, Arvind, Chaparro-Riggers, Javier

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