Induction of Heart Valve Lesions by Small-Molecule ALK5 Inhibitors von Anderton, Mark J., Mellor, Howard R., Bell, Alex, Sadler, Claire, Pass, Martin, Powell, Steve, Steele, Samantha J., Roberts, Ruth. R. A., Heier, Annabelle

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Hydrostatic pressure regulates CYP1A2 expression in human hepatocytes via a mechanosensitive aryl hydrocarbon receptor-dependent pathway von Burton, Lewis, Scaife, Paula, Paine, Stuart W., Mellor, Howard R., Abernethy, Lynn, Littlewood, Peter, Rauch, Cyril

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Resistance to Chemotherapy in Cancer: A Complex and Integrated Cellular Response von Mellor, Howard R., Callaghan, Richard

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The role of the hypoxia-inducible BH3-only proteins BNIP3 and BNIP3L in cancer von Mellor, Howard R, Harris, Adrian L

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An integrated characterization of serological, pathological, and functional events in doxorubicin-induced cardiotoxicity von Cove-Smith, Laura, Woodhouse, Neil, Hargreaves, Adam, Kirk, Jason, Smith, Susan, Price, Sally A, Galvin, Melanie, Betts, Catherine J, Brocklehurst, Simon, Backen, Alison, Radford, John, Linton, Kim, Roberts, Ruth A, Schmitt, Matthias, Dive, Caroline, Tugwood, Jonathan D, Hockings, Paul D, Mellor, Howard R

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Targeted inhibition of the FGF19-FGFR4 pathway in hepatocellular carcinoma; translational safety considerations von Mellor, Howard R.

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Basis for Design and Development of Platinum(IV) Anticancer Complexes von Hall, Matthew D, Mellor, Howard R, Callaghan, Richard, Hambley, Trevor W

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The Role of ATF4 Stabilization and Autophagy in Resistance of Breast Cancer Cells Treated with Bortezomib von MILANI, Manuela, RZYMSKI, Tomasz, MELLOR, Howard R, PIKE, Luke, BOTTINI, Alberto, GENERALI, Daniele, HARRIES, Adrian L

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Cardiotoxicity associated with targeting kinase pathways in cancer von Mellor, Howard R, Bell, Alex R, Valentin, Jean-Pierre, Roberts, Ruth R A

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Modulation of multidrug resistance efflux pump activity to overcome chemoresistance in cancer von Modok, Szabolcs, Mellor, Howard R, Callaghan, Richard

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Gender differences in drug toxicity von Nicolson, Tamara J, Mellor, Howard R, Roberts, Ruth R.A

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Reducing attrition in drug development: smart loading preclinical safety assessment von Roberts, Ruth A., Kavanagh, Stefan L., Mellor, Howard R., Pollard, Christopher E., Robinson, Sally, Platz, Stefan J.

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Accumulation and distribution of doxorubicin in tumour spheroids: the influence of acidity and expression of P-glycoprotein von Mellor, Howard R., Callaghan, Richard

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Small–molecule therapeutics for the treatment of glycolipid lysosomal storage disorders von Butters, Terry D., Mellor, Howard R., Narita, Keishi, Dwek, Raymond A., Platt, Frances M.

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Membrane disruption and cytotoxicity of hydrophobic N-alkylated imino sugars is independent of the inhibition of protein and lipid glycosylation von Mellor, Howard R, Platt, Frances M, Dwek, Raymond A, Butters, Terry D

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Preparation, biochemical characterization and biological properties of radiolabelled N-alkylated deoxynojirimycins von Mellor, Howard R, Nolan, James, Pickering, Lea, Wormald, Mark R, Platt, Frances M, Dwek, Raymond A, Fleet, George W J, Butters, Terry D

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Cellular effects of deoxynojirimycin analogues: uptake, retention and inhibition of glycosphingolipid biosynthesis von Mellor, Howard R, Neville, David C A, Harvey, David J, Platt, Frances M, Dwek, Raymond A, Butters, Terry D

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Cellular effects of deoxynojirimycin analogues: inhibition of N-linked oligosaccharide processing and generation of free glucosylated oligosaccharides von Mellor, Howard R, Neville, David C A, Harvey, David J, Platt, Frances M, Dwek, Raymond A, Butters, Terry D

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Towards better models and mechanistic biomarkers for drug-induced gastrointestinal injury von Carr, Daniel F, Ayehunie, Seyoum, Davies, Andrea, Duckworth, Carrie A, French, Stephanie, Hall, Neil, Hussain, Syed, Mellor, Howard R, Norris, Alan, Park, B Kevin, Penrose, Alexander, Pritchard, D Mark, Probert, Chris S, Ramaiah, Shashi, Sadler, Claire, Schmitt, Michael, Shaw, Alison, Sidaway, James E, Vries, Robert G, Wagoner, Matthew, Pirmohamed, Munir

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Elemental Tomography of Cancer-Cell Spheroids Reveals Incomplete Uptake of Both Platinum(II) and Platinum(IV) Complexes von Alderden, Rebecca A, Mellor, Howard R, Modok, Szabolcs, Hall, Matthew D, Sutton, Stephen R, Newville, Matthew G, Callaghan, Richard, Hambley, Trevor W

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