Dendritic cells: master regulators of the immune response von Mellman, Ira

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Antibody Therapeutics in Cancer von Sliwkowski, Mark X., Mellman, Ira

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IL-1 and IL-1ra are key regulators of the inflammatory response to RNA vaccines von Tahtinen, Siri, Tong, Ann-Jay, Himmels, Patricia, Oh, Jaehak, Paler-Martinez, Andres, Kim, Leesun, Wichner, Sara, Oei, Yoko, McCarron, Mark J., Freund, Emily C., Amir, Zhainib Adel, de la Cruz, Cecile C., Haley, Benjamin, Blanchette, Craig, Schartner, Jill M., Ye, Weilan, Yadav, Mahesh, Sahin, Ugur, Delamarre, Lélia, Mellman, Ira

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TIGIT-CD226-PVR axis: advancing immune checkpoint blockade for cancer immunotherapy von Chiang, Eugene Y, Mellman, Ira

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Coordinated protein sorting, targeting and distribution in polarized cells von Mellman, Ira, Nelson, W. James

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Molecular determinants of response to PD-L1 blockade across tumor types von Banchereau, Romain, Leng, Ning, Zill, Oliver, Sokol, Ethan, Liu, Gengbo, Pavlick, Dean, Maund, Sophia, Liu, Li-Fen, Kadel, Edward, Baldwin, Nicole, Jhunjhunwala, Suchit, Nickles, Dorothee, Assaf, Zoe June, Bower, Daniel, Patil, Namrata, McCleland, Mark, Shames, David, Molinero, Luciana, Huseni, Mahrukh, Sanjabi, Shomyseh, Cummings, Craig, Mellman, Ira, Mariathasan, Sanjeev, Hegde, Priti, Powles, Thomas

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Spatial control of EGF receptor activation by reversible dimerization on living cells von Chung, Inhee, Akita, Robert, Vandlen, Richard, Toomre, Derek, Schlessinger, Joseph, Mellman, Ira

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Genetic variation associated with thyroid autoimmunity shapes the systemic immune response to PD-1 checkpoint blockade von Khan, Zia, Hammer, Christian, Carroll, Jonathan, Di Nucci, Flavia, Acosta, Sergio Ley, Maiya, Vidya, Bhangale, Tushar, Hunkapiller, Julie, Mellman, Ira, Albert, Matthew L., McCarthy, Mark I., Chandler, G. Scott

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Single-cell analysis of human non-small cell lung cancer lesions refines tumor classification and patient stratification von Leader, Andrew M., Grout, John A., Maier, Barbara B., Nabet, Barzin Y., Park, Matthew D., Tabachnikova, Alexandra, Chang, Christie, Walker, Laura, Lansky, Alona, Le Berichel, Jessica, Troncoso, Leanna, Malissen, Nausicaa, Davila, Melanie, Martin, Jerome C., Magri, Giuliana, Tuballes, Kevin, Zhao, Zhen, Petralia, Francesca, Samstein, Robert, D’Amore, Natalie Roy, Thurston, Gavin, Kamphorst, Alice O., Wolf, Andrea, Flores, Raja, Wang, Pei, Müller, Sören, Mellman, Ira, Beasley, Mary Beth, Salmon, Hélène, Rahman, Adeeb H., Marron, Thomas U., Kenigsberg, Ephraim, Merad, Miriam

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Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients von Herbst, Roy S., Soria, Jean-Charles, Kowanetz, Marcin, Fine, Gregg D., Hamid, Omid, Gordon, Michael S., Sosman, Jeffery A., McDermott, David F., Powderly, John D., Gettinger, Scott N., Kohrt, Holbrook E. K., Horn, Leora, Lawrence, Donald P., Rost, Sandra, Leabman, Maya, Xiao, Yuanyuan, Mokatrin, Ahmad, Koeppen, Hartmut, Hegde, Priti S., Mellman, Ira, Chen, Daniel S., Hodi, F. Stephen

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Cell biology of antigen processing in vitro and in vivo von Trombetta, E Sergio, Mellman, Ira

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Tumour and host cell PD-L1 is required to mediate suppression of anti-tumour immunity in mice von Lau, Janet, Cheung, Jeanne, Navarro, Armando, Lianoglou, Steve, Haley, Benjamin, Totpal, Klara, Sanders, Laura, Koeppen, Hartmut, Caplazi, Patrick, McBride, Jacqueline, Chiu, Henry, Hong, Rebecca, Grogan, Jane, Javinal, Vincent, Yauch, Robert, Irving, Bryan, Belvin, Marcia, Mellman, Ira, Kim, Jeong M., Schmidt, Maike

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Transposable element expression in tumors is associated with immune infiltration and increased antigenicity von Kong, Yu, Rose, Christopher M., Cass, Ashley A., Williams, Alexander G., Darwish, Martine, Lianoglou, Steve, Haverty, Peter M., Tong, Ann-Jay, Blanchette, Craig, Albert, Matthew L., Mellman, Ira, Bourgon, Richard, Greally, John, Jhunjhunwala, Suchit, Chen-Harris, Haiyin

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ENDOCYTOSIS AND MOLECULAR SORTING von Mellman, Ira

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Germline genetic polymorphisms influence tumor gene expression and immune cell infiltration von Lim, Yoong Wearn, Chen-Harris, Haiyin, Mayba, Oleg, Lianoglou, Steve, Wuster, Arthur, Bhangale, Tushar, Khan, Zia, Mariathasan, Sanjeev, Daemen, Anneleen, Reeder, Jens, Haverty, Peter M., Forrest, William F., Brauer, Matthew, Mellman, Ira, Albert, Matthew L.

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Polygenic risk for skin autoimmunity impacts immune checkpoint blockade in bladder cancer von Khan, Zia, Di Nucci, Flavia, Kwan, Antonia, Hammer, Christian, Mariathasan, Sanjeev, Rouilly, Vincent, Carroll, Jonathan, Fontes, Magnus, Acosta, Sergio Ley, Guardino, Ellie, Chen-Harris, Haiyin, Bhangale, Tushar, Mellman, Ira, Rosenberg, Jonathan, Powles, Thomas, Hunkapiller, Julie, Chandler, G. Scott, Albert, Matthew L.

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The Prioritization of Cancer Antigens: A National Cancer Institute Pilot Project for the Acceleration of Translational Research von CHEEVER, Martin A, ALLISON, James P, MATRISIAN, Lynn M, FERRIS, Andrea S, FINN, Olivera J, HASTINGS, Benjamin M, HECHT, Toby T, MELLMAN, Ira, PRINDIVILLE, Sheila A, VINER, Jaye L, WEINER, Louis M

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Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity von Maurer, Till, Garrenton, Lindsay S, Oh, Angela, Pitts, Keith, Anderson, Daniel J, Skelton, Nicholas J, Fauber, Benjamin P, Pan, Borlan, Malek, Shiva, Stokoe, David, Ludlam, Mary J. C, Bowman, Krista K, Wu, Jiansheng, Giannetti, Anthony M, Starovasnik, Melissa A, Mellman, Ira, Jackson, Peter K, Rudolph, Joachim, Wang, Weiru, Fang, Guowei

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Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation von Vander Lugt, Bryan, Khan, Aly A, Hackney, Jason A, Agrawal, Smita, Lesch, Justin, Zhou, Meijuan, Lee, Wyne P, Park, Summer, Xu, Min, DeVoss, Jason, Spooner, Chauncey J, Chalouni, Cecile, Delamarre, Lelia, Mellman, Ira, Singh, Harinder

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Transcriptional determinants of tolerogenic and immunogenic states during dendritic cell maturation von Vander Lugt, Bryan, Riddell, Jeremy, Khan, Aly A, Hackney, Jason A, Lesch, Justin, DeVoss, Jason, Weirauch, Matthew T, Singh, Harinder, Mellman, Ira

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