Structural tuning of organoruthenium compounds allows oxidative switch to control ER stress pathways and bypass multidrug resistance von Chow, Mun Juinn, Licona, Cynthia, Pastorin, Giorgia, Mellitzer, Georg, Ang, Wee Han, Gaiddon, Christian

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Distinct ATOH1 and Neurog3 requirements define tuft cells as a new secretory cell type in the intestinal epithelium von Gerbe, François, van Es, Johan H, Makrini, Leila, Brulin, Bénédicte, Mellitzer, Georg, Robine, Sylvie, Romagnolo, Béatrice, Shroyer, Noah F, Bourgaux, Jean-François, Pignodel, Christine, Clevers, Hans, Jay, Philippe

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Bypassing the Resistance Mechanisms of the Tumor Ecosystem by Targeting the Endoplasmic Reticulum Stress Pathway Using Ruthenium- and Osmium-Based Organometallic Compounds: An Exci... von Gaiddon, Christian, Gross, Isabelle, Meng, Xiangjun, Sidhoum, Marjorie, Mellitzer, Georg, Romain, Benoit, Delhorme, Jean-Batiste, Venkatasamy, Aïna, Jung, Alain C., Pfeffer, Michel

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The atypical cadherin MUCDHL antagonizes colon cancer formation and inhibits oncogenic signaling through multiple mechanisms von Beck, Marine, Baranger, Mathilde, Moufok-Sadoun, Ahlam, Bersuder, Emilie, Hinkel, Isabelle, Mellitzer, Georg, Martin, Elisabeth, Marisa, Laetitia, Duluc, Isabelle, de Reynies, Aurelien, Gaiddon, Christian, Freund, Jean-Noel, Gross, Isabelle

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Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development von Soyer, Josselin, Flasse, Lydie, Raffelsberger, Wolfgang, Beucher, Anthony, Orvain, Christophe, Peers, Bernard, Ravassard, Philippe, Vermot, Julien, Voz, Marianne L, Mellitzer, Georg, Gradwohl, Gérard

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A novel ΔNp63-dependent immune mechanism improves prognosis of HPV-related head and neck cancer von Mourtada, Jana, Lony, Christelle, Nicol, Anaïs, De Azevedo, Justine, Bour, Cyril, Macabre, Christine, Roncarati, Patrick, Ledrappier, Sonia, Schultz, Philippe, Borel, Christian, Burgy, Mickaël, Wasylyk, Bohdan, Mellitzer, Georg, Herfs, Michaël, Gaiddon, Christian, Jung, Alain C

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Loss of enteroendocrine cells in mice alters lipid absorption and glucose homeostasis and impairs postnatal survival von Mellitzer, Georg, Beucher, Anthony, Lobstein, Viviane, Michel, Pascal, Robine, Sylvie, Kedinger, Michèle, Gradwohl, Gérard

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A ruthenium anticancer compound interacts with histones and impacts differently on epigenetic and death pathways compared to cisplatin von Licona, Cynthia, Spaety, Marie-Elodie, Capuozzo, Antonelle, Ali, Moussa, Santamaria, Rita, Armant, Olivier, Delalande, Francois, Van Dorsselaer, Alain, Cianferani, Sarah, Spencer, John, Pfeffer, Michel, Mellitzer, Georg, Gaiddon, Christian

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Transcriptional activator TAp63 is upregulated in muscular atrophy during ALS and induces the pro-atrophic ubiquitin ligase Trim63 von von Grabowiecki, Yannick, Abreu, Paula, Blanchard, Orphee, Palamiuc, Lavinia, Benosman, Samir, Mériaux, Sophie, Devignot, Véronique, Gross, Isabelle, Mellitzer, Georg, Gonzalez de Aguilar, José L, Gaiddon, Christian

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Regulation of a Notch3-Hes1 Pathway and Protective Effect by a Tocopherol-Omega Alkanol Chain Derivative in Muscle Atrophy von von Grabowiecki, Yannick, Licona, Cynthia, Palamiuc, Lavinia, Abreu, Paula, Vidimar, Vania, Coowar, Djalil, Mellitzer, Georg, Gaiddon, Christian

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Eph receptors and ephrins restrict cell intermingling and communication von Mellitzer, Georg, Xu, Qiling, Wilkinson, David G.

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The EXTREME Regimen Associating Cetuximab and Cisplatin Favors Head and Neck Cancer Cell Death and Immunogenicity with the Induction of an Anti-Cancer Immune Response von De Azevedo, Justine, Mourtada, Jana, Bour, Cyril, Devignot, Véronique, Schultz, Philippe, Borel, Christian, Pencreach, Erwan, Mellitzer, Georg, Gaiddon, Christian, Jung, Alain C

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Ultrasound and Transcriptomics Identify a Differential Impact of Cisplatin and Histone Deacetylation on Tumor Structure and Microenvironment in a Patient-Derived In Vivo Model of G... von Venkatasamy, Aina, Guerin, Eric, Blanchet, Anais, Orvain, Christophe, Devignot, Véronique, Jung, Matthieu, Jung, Alain C, Chenard, Marie-Pierre, Romain, Benoit, Gaiddon, Christian, Mellitzer, Georg

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In vivo cell sorting in complementary segmental domains mediated by Eph receptors and ephrins von Xu, Qiling, Mellitzer, Georg, Robinson, Vicky, Wilkinson, David G.

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Conditional deletion of neurogenin-3 using Nkx2.1iCre results in a mouse model for the central control of feeding, activity and obesity von Anthwal, Neal, Pelling, Michelle, Claxton, Suzanne, Mellitzer, Georg, Collin, Caitlin, Kessaris, Nicoletta, Richardson, William D, Gradwohl, Gérard, Ang, Siew-Lan

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Histone Deacetylase Functions in Gastric Cancer: Therapeutic Target? von Badie, Amandine, Gaiddon, Christian, Mellitzer, Georg

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Pancreatic Islet Progenitor Cells in Neurogenin 3-Yellow Fluorescent Protein Knock-Add-On Mice von Mellitzer, Georg, Martín, Mercè, Sidhoum-Jenny, Marjorie, Orvain, Christophe, Barths, Jochen, Seymour, Philip A, Sander, Maike, Gradwohl, Gérard

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Isoforms of the p53 Family and Gastric Cancer: A Ménage à Trois for an Unfinished Affair von Blanchet, Anais, Bourgmayer, Agathe, Kurtz, Jean-Emmanuel, Mellitzer, Georg, Gaiddon, Christian

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Platinum(II) and Ruthenium(II) Coordination complexes equipped with an anchoring site for binding the protein kinase enzyme pockets: synthesis, molecular docking and biological ass... von Scarpi-Luttenauer, Matthieu, galentino, katia, Orvain, Christophe, FLUCK, Audrey, Cecchini, Marco, Mellitzer, Georg, Gaiddon, Christian, Mobian, Pierre

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β Cells Can Be Generated from Endogenous Progenitors in Injured Adult Mouse Pancreas von Xu, Xiaobo, D'Hoker, Joke, Stangé, Geert, Bonné, Stefan, De Leu, Nico, Xiao, Xiangwei, Van De Casteele, Mark, Mellitzer, Georg, Ling, Zhidong, Pipeleers, Danny, Bouwens, Luc, Scharfmann, Raphael, Gradwohl, Gerard, Heimberg, Harry

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