Acid ceramidase deficiency: Farber disease and SMA-PME von Yu, Fabian P S, Amintas, Samuel, Levade, Thierry, Medin, Jeffrey A

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Lentivirus-mediated gene therapy for Fabry disease von Khan, Aneal, Barber, Dwayne L., Huang, Ju, Rupar, C. Anthony, Rip, Jack W., Auray-Blais, Christiane, Boutin, Michel, O’Hoski, Pamela, Gargulak, Kristy, McKillop, William M., Fraser, Graeme, Wasim, Syed, LeMoine, Kaye, Jelinski, Shelly, Chaudhry, Ahsan, Prokopishyn, Nicole, Morel, Chantal F., Couban, Stephen, Duggan, Peter R., Fowler, Daniel H., Keating, Armand, West, Michael L., Foley, Ronan, Medin, Jeffrey A.

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Genetic ablation of acid ceramidase in Krabbe disease confirms the psychosine hypothesis and identifies a new therapeutic target von Li, Yedda, Xu, Yue, Benitez, Bruno A., Nagree, Murtaza S., Dearborn, Joshua T., Jiang, Xuntian, Guzman, Miguel A., Woloszynek, Josh C., Giaramita, Alex, Yip, Bryan K., Elsbernd, Joseph, Babcock, Michael C., Lo, Melanie, Fowler, Stephen C., Wozniak, David F., Vogler, Carole A., Medin, Jeffrey A., Crawford, Brett E., Sands, Mark S.

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The engineered thymidylate kinase (TMPK)/AZT enzyme-prodrug axis offers efficient bystander cell killing for suicide gene therapy of cancer von Sato, Takeya, Neschadim, Anton, Lavie, Arnon, Yanagisawa, Teruyuki, Medin, Jeffrey A

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Neuraminidase 1 activates insulin receptor and reverses insulin resistance in obese mice von Fougerat, Anne, Pan, Xuefang, Smutova, Victoria, Heveker, Nikolaus, Cairo, Christopher W., Issad, Tarik, Larrivée, Bruno, Medin, Jeffrey A., Pshezhetsky, Alexey V.

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Ceramide metabolism alterations contribute to Tumor Necrosis Factor-induced melanoma dedifferentiation and predict resistance to immune checkpoint inhibitors in advanced melanoma p... von Dufau, Carine, Genais, Matthieu, Mucher, Elodie, Jung, Benjamin, Garcia, Virginie, Montfort, Anne, Tosolini, Marie, Clarke, Christopher J, Medin, Jeffrey A, Levade, Thierry, Delord, Jean-Pierre, Meyer, Nicolas, Pancaldi, Vera, Andrieu-Abadie, Nathalie, Ségui, Bruno

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Diet quality on days without breakfast or lunch – Identifying targets to improve adolescents’ diet von Medin, A.C., Myhre, J.B., Diep, L.M., Andersen, L.F.

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On-Tissue Localization of Ceramides and Other Sphingolipids by MALDI Mass Spectrometry Imaging von Jones, E. Ellen, Dworski, Shaalee, Canals, Daniel, Casas, Josefina, Fabrias, Gemma, Schoenling, Drew, Levade, Thierry, Denlinger, Chadrick, Hannun, Yusuf A, Medin, Jeffrey A, Drake, Richard R

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Sarcoma IL-12 overexpression facilitates NK cell immunomodulation von Rademacher, Mary Jo, Cruz, Anahi, Faber, Mary, Oldham, Robyn A. A., Wang, Dandan, Medin, Jeffrey A., Schloemer, Nathan J.

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Acid Ceramidase Deficiency: Bridging Gaps between Clinical Presentation, Mouse Models, and Future Therapeutic Interventions von Kleynerman, Annie, Rybova, Jitka, Faber, Mary L, McKillop, William M, Levade, Thierry, Medin, Jeffrey A

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Lentivirus IL‐10 Gene Therapy Down‐Regulates IL‐17 and Attenuates Mouse Orthotopic Lung Allograft Rejection von Hirayama, S., Sato, M., Loisel‐Meyer, S., Matsuda, Y., Oishi, H., Guan, Z., Saito, T., Yeung, J., Cypel, M., Hwang, D. M., Medin, J. A., Liu, M., Keshavjee, S.

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Novel anti-CD30/CD3 bispecific antibodies activate human T cells and mediate potent anti-tumor activity von Faber, Mary L, Oldham, Robyn A A, Thakur, Archana, Rademacher, Mary Jo, Kubicka, Ewa, Dlugi, Theresa A, Gifford, Steven A, McKillop, William M, Schloemer, Nathan J, Lum, Lawrence G, Medin, Jeffrey A

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Autologous, lentivirus‐modified, T‐rapa cell “micropharmacies” for lysosomal storage disorders von Nagree, Murtaza S, Felizardo, Tania C, Faber, Mary L, Rybova, Jitka, Rupar, C Anthony, Foley, S Ronan, Fuller, Maria, Fowler, Daniel H, Medin, Jeffrey A

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Natural killer cell lines preferentially kill clonogenic multiple myeloma cells and decrease myeloma engraftment in a bioluminescent xenograft mouse model von SWIFT, Brenna E, WILLIAMS, Brent A, KOSAKA, Yoko, WANG, Xing-Hua, MEDIN, Jeffrey A, VISWANATHAN, Sowmya, MARTINEZ-LOPEZ, Joaquin, KEATING, Armand

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Development of Novel Immunotherapies for Multiple Myeloma von Al-Hujaily, Ensaf M, Oldham, Robyn A A, Hari, Parameswaran, Medin, Jeffrey A

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Systemic ceramide accumulation leads to severe and varied pathological consequences von Alayoubi, Abdulfatah M., Wang, James C. M., Au, Bryan C. Y., Carpentier, Stéphane, Garcia, Virginie, Dworski, Shaalee, El‐Ghamrasni, Samah, Kirouac, Kevin N., Exertier, Mathilde J., Xiong, Zi Jian, Privé, Gilbert G., Simonaro, Calogera M., Casas, Josefina, Fabrias, Gemma, Schuchman, Edward H., Turner, Patricia V., Hakem, Razqallah, Levade, Thierry, Medin, Jeffrey A.

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Smoothed Particle Hydrodynamics Using Interparticle Contact Algorithms von Parshikov, Anatoly N., Medin, Stanislav A.

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Markedly perturbed hematopoiesis in acid ceramidase deficient mice von Dworski, Shaalee, Berger, Alexandra, Furlonger, Caren, Moreau, Joshua M, Yoshimitsu, Makoto, Trentadue, Jessa, Au, Bryan C Y, Paige, Christopher J, Medin, Jeffrey A

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Adiponectin overexpression improves metabolic abnormalities caused by acid ceramidase deficiency but does not prolong lifespan in a mouse model of Farber Disease von Norris, Marie K., Tippetts, Trevor S., Wilkerson, Joseph L., Nicholson, Rebekah J., Maschek, J. Alan, Levade, Thierry, Medin, Jeffrey A., Summers, Scott A., Holland, William L.

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Strategies for Delaying or Treating In vivo Acquired Resistance to Trastuzumab in Human Breast Cancer Xenografts von DU MANOIR, Jeanne M, FRANCIA, Giulio, SHAN MAN, MOSSOBA, Miriam, MEDIN, Jeffrey A, VILORIA-PETIT, Alicia, HICKLIN, Daniel J, EMMENEGGER, Urban, KERBEL, Robert S

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