Discovery of Potent Antagonists of the Antiapoptotic Protein XIAP for the Treatment of Cancer von Oost, Thorsten K, Sun, Chaohong, Armstrong, Robert C, Al-Assaad, Ali-Samer, Betz, Stephen F, Deckwerth, Thomas L, Ding, Hong, Elmore, Steven W, Meadows, Robert P, Olejniczak, Edward T, Oleksijew, Andrew, Oltersdorf, Tilman, Rosenberg, Saul H, Shoemaker, Alexander R, Tomaselli, Kevin J, Zou, Hua, Fesik, Stephen W

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Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain von Liu, Zhihong, Sun, Chaohong, Olejniczak, Edward T., Meadows, Robert P., Betz, Stephen F., Oost, Thorsten, Herrmann, Julia, Wu, Joe C., Fesik, Stephen W.

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Discovering High-Affinity Ligands for Proteins: SAR by NMR von Shuker, Suzanne B., Hajduk, Philip J., Meadows, Robert P., Fesik, Stephen W.

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NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP von Sun, Chaohong, Cai, Mengli, Gunasekera, Angelo H., Meadows, Robert P., Wang, Hong, Chen, Jun, Zhang, Haichao, Wu, Wei, Xu, Nan, Ng, Shi-Chung, Fesik, Stephen W.

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X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death von Muchmore, Steven W., Sattler, Michael, Liang, Heng, Meadows, Robert P., Harlan, John E., Yoon, Ho Sup, Nettesheim, David, Chang, Brian S., Thompson, Craig B., Wong, Sui-Lam, Ng, Shi-Chung, Fesik, Stephen W.

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NMR structure and mutagenesis of the FADD (Mort1) death-effector domain von Eberstadt, Matthias, Huang, Baohua, Chen, Zehan, Meadows, Robert P., Ng, Shi-Chung, Zheng, Lixin, Lenardo, Michael J., Fesik, Stephen W.

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Discovering High-Affinity Ligands for Proteins von Hajduk, Philip J., Meadows, Robert P., Fesik, Stephen W.

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NMR Structure and Mutagenesis of the N-Terminal Dbl Homology Domain of the Nucleotide Exchange Factor Trio von Liu, Xiaohong, Wang, Hong, Eberstadt, Matthias, Schnuchel, Arndt, Olejniczak, Edward T, Meadows, Robert P, Schkeryantz, Jeff M, Janowick, David A, Harlan, John E, Harris, Edith A.S, Staunton, Donald E, Fesik, Stephen W

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Structure of Bcl-x-Bak peptide complex: recognition between regulators of apoptosis von Sattler, Michael, Nettesheim, David, Meadows, Robert P, Harlan, John E, Eberstadt, Matthias, Yoon, Ho Sup, Shuker, Suzanne B, Chang, Brian S, Minn, Andy J, Thompson, Craig B, Fesik, Stephen W

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NMR Structure and Mutagenesis of the Third Bir Domain of the Inhibitor of Apoptosis Protein XIAP von Sun, Chaohong, Cai, Mengli, Meadows, Robert P., Xu, Nan, Gunasekera, Angelo H., Herrmann, Julia, Wu, Joe C., Fesik, Stephen W.

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NMR structure and mutagenesis of the Fas (APO-1/CD95) death domain von Huang, Baohua, Eberstadt, Matthias, Olejniczak, Edward T., Meadows, Robert P., Fesik, Stephen W.

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Solution Structure of the Amino-Terminal Fragment of Urokinase-Type Plasminogen Activator von Hansen, Andrew P, Petros, Andrew M, Meadows, Robert P, Nettesheim, David G, Mazar, Andrew P, Olejniczak, Edward T, Xu, Robert X, Pederson, Terry M, Henkin, Jack, Fesik, Stephen W

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Structure and ligand recognition of the phosphotyrosine binding domain of Shc von Zhou, Ming-Ming, Ravichandran, Kodimangalam S., Olejniczak, Edward T., Petros, Andrew M., Meadows, Robert P., Sattler, Michael, Harlan, John E., Wade, Warren S., Burakoff, Steven J., Fesik, Stephen W.

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Discovery of Potent Inhibitors of Dihydroneopterin Aldolase Using CrystaLEAD High-Throughput X-ray Crystallographic Screening and Structure-Directed Lead Optimization von Sanders, William J, Nienaber, Vicki L, Lerner, Claude G, McCall, J. Owen, Merrick, Sean M, Swanson, Susan J, Harlan, John E, Stoll, Vincent S, Stamper, Geoffrey F, Betz, Stephen F, Condroski, Kevin R, Meadows, Robert P, Severin, Jean M, Walter, Karl A, Magdalinos, Peter, Jakob, Clarissa G, Wagner, Rolf, Beutel, Bruce A

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Non-peptidic small molecule inhibitors of XIAP von Park, Cheol-Min, Sun, Chaohong, Olejniczak, Edward T., Wilson, Alan E., Meadows, Robert P., Betz, Stephen F., Elmore, Steven W., Fesik, Stephen W.

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NMR-Based Modification of Matrix Metalloproteinase Inhibitors with Improved Bioavailability von Hajduk, Philip J, Shuker, Suzanne B, Nettesheim, David G, Craig, Richard, Augeri, David J, Betebenner, David, Albert, Daniel H, Guo, Yan, Meadows, Robert P, Xu, Lianhong, Michaelides, Michael, Davidsen, Steven K, Fesik, Stephen W

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Solution structure of a pleckstrin-homology domain von Yoon, Ho Sup, Hajduk, Philip J., Petros, Andrew M., Olejniczak, Edward T., Meadows, Robert P., Fesik, Stephen W.

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Heteronuclear 3D NMR studies of water bound to an FK506 binding protein/immunosuppressant complex von Xu, Robert X, Meadows, Robert P, Fesik, Stephen W

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A liquid crystalline medium for measuring residual dipolar couplings over a wide range of temperatures von Wang, Hong, Eberstadt, Matthias, Olejniczak, Edward T, Meadows, Robert P, Fesik, Stephen W

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Two-dimensional NMR and structure determination of salmon calcitonin in methanol von Meadows, Robert P, Nikonowicz, Edward P, Jones, Claude R, Bastian, James W, Gorenstein, David G

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