Pd-Catalyzed N-Arylation of Heteroarylamines von Yin, Jingjun, Zhao, Matthew M, Huffman, Mark A, McNamara, James M

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Efficient Synthesis of NK1 Receptor Antagonist Aprepitant Using a Crystallization-Induced Diastereoselective Transformation von Brands, Karel M. J, Payack, Joseph F, Rosen, Jonathan D, Nelson, Todd D, Candelario, Alexander, Huffman, Mark A, Zhao, Matthew M, Li, Jing, Craig, Bridgette, Song, Zhiguo J, Tschaen, David M, Hansen, Karl, Devine, Paul N, Pye, Philip J, Rossen, Kai, Dormer, Peter G, Reamer, Robert A, Welch, Christopher J, Mathre, David J, Tsou, Nancy N, McNamara, James M, Reider, Paul J

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Stereoselective Synthesis of a Potent Thrombin Inhibitor by a Novel P2−P3 Lactone Ring Opening von Nelson, Todd D, LeBlond, Carl R, Frantz, Doug E, Matty, Louis, Mitten, Jeffrey V, Weaver, Damian G, Moore, Jeffrey C, Kim, Jaehon M, Boyd, Russell, Kim, Pei-Yi, Gbewonyo, Kodzo, Brower, Mark, Sturr, Michael, McLaughlin, Kathleen, McMasters, Daniel R, Kress, Michael H, McNamara, James M, Dolling, Ulf H

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Practical Asymmetric Synthesis of Aprepitant, a Potent Human NK-1 Receptor Antagonist, via a Stereoselective Lewis Acid-Catalyzed Trans Acetalization Reaction von Zhao, Matthew M, McNamara, James M, Ho, Guo-Jie, Emerson, Khateeta M, Song, Zhiguo J, Tschaen, David M, Brands, Karel M. J, Dolling, Ulf-H, Grabowski, Edward J. J, Reider, Paul J, Cottrell, Ian F, Ashwood, Michael S, Bishop, Brian C

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Synthesis of a Tetrahydropyran NK1 Receptor Antagonist via Asymmetric Conjugate Addition von Huffman, Mark A, Smitrovich, Jacqueline H, Rosen, Jonathan D, Boice, Geneviève N, Qu, Chuanxing, Nelson, Todd D, McNamara, James M

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Practical routes to the triarylsulfonyl chloride intermediate of a β3 adrenergic receptor agonist von Ikemoto, Norihiro, Liu, Jinchu, Brands, Karel M.J, McNamara, James M, Reider, Paul J

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A very concise synthesis of a potent N-(1,3-thiazol-2-yl)pyridin-2-amine KDR kinase inhibitor von Zhao, Matthew, Yin, Jingjun, Huffman, Mark A., McNamara, James M.

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Synthesis of a NO-Releasing Prodrug of Rofecoxib von Engelhardt, F. Conrad, Shi, Yao-Jun, Cowden, Cameron J, Conlon, David A, Pipik, Brenda, Zhou, George, McNamara, James M, Dolling, Ulf-H

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Efficient Synthesis of a Highly Selective NPY-5 Receptor Antagonist:  A Drug Candidate for the Treatment of Obesity von Itoh, Takahiro, Kato, Shinji, Nonoyama, Nobuaki, Wada, Toshihiro, Maeda, Kenji, Mase, Toshiaki, Zhao, Matthew M, Song, Jake Z, Tschaen, David M, McNamara, James M

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Process Development and Large-Scale Synthesis of a PDE4 Inhibitor von Conlon, David A, Drahus-Paone, Antoinette, Ho, Guo-Jie, Pipik, Brenda, Helmy, Roy, McNamara, James M, Shi, Yao-Jun, Williams, J. Michael, Macdonald, Dwight, Deschênes, Denis, Gallant, Michel, Mastracchio, Anthony, Roy, Bruno, Scheigetz, John

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One-Pot Preparation of 7-Hydroxyquinoline von Cameron, Mark, Hoerrner, R. Scott, McNamara, James M, Figus, Margaret, Thomas, Scott

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A regioselective synthesis of 2,4-dialkyl resorcinols von Ceglia, Scott S., Kress, Michael H., Nelson, Todd D., McNamara, James M.

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Effective use of preparative chiral HPLC in a preclinical drug synthesis von Nelson, Todd D., Welch, Christopher J., Rosen, Jonathan D., Smitrovich, Jacqueline H., Huffman, Mark A., McNamara, James M., Mathre, David J.

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A convenient synthesis of 3-aryl-δ-lactones von Rosen, Jonathan D, Nelson, Todd D, Huffman, Mark A, McNamara, James M

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Practical chemoenzymatic synthesis of a 3-pyridylethanolamino β3 adrenergic receptor agonist von Chung, John Y.L, Ho, Guo-Jie, Chartrain, Michel, Roberge, Chris, Zhao, Dalian, Leazer, John, Farr, Roger, Robbins, Michael, Emerson, Kateeta, Mathre, David J, McNamara, James M, Hughes, David L, Grabowski, Edward J.J, Reider, Paul J

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Targeting of memory T cells with alefacept in new-onset type 1 diabetes (T1DAL study): 12 month results of a randomised, double-blind, placebo-controlled phase 2 trial von Rigby, Mark R, Prof, DiMeglio, Linda A, Prof, Rendell, Marc S, MD, Felner, Eric I, Prof, Dostou, Jean M, Prof, Gitelman, Stephen E, Prof, Patel, Chetanbabu M, MD, Griffin, Kurt J, Prof, Tsalikian, Eva, Prof, Gottlieb, Peter A, Prof, Greenbaum, Carla J, MD, Sherry, Nicole A, MD, Moore, Wayne V, MD, Monzavi, Roshanak, MD, Willi, Steven M, MD, Raskin, Philip, Prof, Moran, Antoinette, Prof, Russell, William E, Prof, Pinckney, Ashley, MS, Keyes-Elstein, Lynette, DrPH, Howell, Michael, PhD, Aggarwal, Sudeepta, PhD, Lim, Noha, PhD, Phippard, Deborah, PhD, Nepom, Gerald T, MD, McNamara, James, MD, Ehlers, Mario R, MBChB

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Multicentre search for genetic susceptibility loci in sporadic epilepsy syndrome and seizure types: a case-control study von Cavalleri, Gianpiero L, PhD, Weale, Michael E, PhD, Shianna, Kevin V, PhD, Singh, Rinki, MD, Lynch, John M, MD, Grinton, Bronwyn, BSc, Szoeke, Cassandra, PhD, Murphy, Kevin, MD, Kinirons, Peter, MD, O'Rourke, Deirdre, MD, Ge, Dongliang, PhD, Depondt, Chantal, PhD, Claeys, Kristl G, PhD, Pandolfo, Massimo, MD, Gumbs, Curtis, BS, Walley, Nicole, BS, McNamara, James, MD, Mulley, John C, PhD, Linney, Kristen N, RN, Sheffield, Leslie J, FRACP, Radtke, Rodney A, MD, Tate, Sarah K, PhD, Chissoe, Stephanie L, PhD, Gibson, Rachel A, PhD, Hosford, David, MD, Stanton, Alice, PhD, Graves, Tracey D, MRCP, Hanna, Michael G, FRCP, Eriksson, Kai, MD, Kantanen, Anne-Mari, MD, Kalviainen, Reetta, MD, O'Brien, Terence J, MD, Sander, Josemir W, MD, FRCP, Duncan, John S, FCRP, Scheffer, Ingrid E, PhD, Berkovic, Samuel F, MD, Wood, Nicholas W, FRCP, Doherty, Colin P, MRCPI, Delanty, Norman, FRCPI, Sisodiya, Sanjay M, PhD, Goldstein, David B, PhD

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Stereospecific synthesis of chiral tertiary alkyl-aryl ethers via Mitsunobu reaction with complete inversion of configuration von Shi, Yao-Jun, Hughes, David L., McNamara, James M.

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Aluminum-Amine Complexes for the Conversion of Carboxylic Esters to Amides. Application to the Synthesis of LTD4 Antagonist MK-0679 von Sidler, Daniel R, Lovelace, Thomas C, McNamara, James M, Reider, Paul J

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A Highly Efficient Synthesis of Fibrinogen Receptor Antagonist L-734,217 via a Novel Chemoselective Silyl-Mediated Conjugate Addition of δ-Lactams to 4-Vinylpyridine von Chung, John Y. L, Hughes, David L, Zhao, Dalian, Song, Zhiguo, Mathre, David J, Ho, Guo-Jie, McNamara, James M, Douglas, Alan W, Reamer, R. A, Tsay, Fuh-Rong, Varsolona, Richard, McCauley, James, Grabowski, Edward J. J, Reider, Paul J

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