Suppression of Somatic Expansion Delays the Onset of Pathophysiology in a Mouse Model of Huntington's Disease von Budworth, Helen, Harris, Faye R, Williams, Paul, Lee, Do Yup, Holt, Amy, Pahnke, Jens, Szczesny, Bartosz, Acevedo-Torres, Karina, Ayala-Peña, Sylvette, McMurray, Cynthia T

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Metabolic Reprogramming in Astrocytes Distinguishes Region-Specific Neuronal Susceptibility in Huntington Mice von Polyzos, Aris A., Lee, Do Yup, Datta, Rupsa, Hauser, Meghan, Budworth, Helen, Holt, Amy, Mihalik, Stephanie, Goldschmidt, Pike, Frankel, Ken, Trego, Kelly, Bennett, Michael J., Vockley, Jerry, Xu, Ke, Gratton, Enrico, McMurray, Cynthia T.

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Close encounters: Moving along bumps, breaks, and bubbles on expanded trinucleotide tracts von Polyzos, Aris A., McMurray, Cynthia T.

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Base excision repair and double strand break repair cooperate to modulate the formation of unrepaired double strand breaks in mouse brain von Polyzos, Aris A., Cheong, Ana, Yoo, Jung Hyun, Blagec, Lana, Toprani, Sneh M., Nagel, Zachary D., McMurray, Cynthia T.

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Mechanisms of trinucleotide repeat instability during human development von McMurray, Cynthia T.

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Features of trinucleotide repeat instability in vivo von Kovtun, Irina V, McMurray, Cynthia T

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Targeting of XJB-5-131 to Mitochondria Suppresses Oxidative DNA Damage and Motor Decline in a Mouse Model of Huntington’s Disease von Xun, Zhiyin, Rivera-Sánchez, Sulay, Ayala-Peña, Sylvette, Lim, James, Budworth, Helen, Skoda, Erin M., Robbins, Paul D., Niedernhofer, Laura J., Wipf, Peter, McMurray, Cynthia T.

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XJB-5-131-mediated improvement in physiology and behaviour of the R6/2 mouse model of Huntington's disease is age- and sex- dependent von Polyzos, Aris A, Wood, Nigel I, Williams, Paul, Wipf, Peter, Morton, A Jennifer, McMurray, Cynthia T

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Crosstalk between MSH2–MSH3 and polβ promotes trinucleotide repeat expansion during base excision repair von Lai, Yanhao, Budworth, Helen, Beaver, Jill M., Chan, Nelson L. S., Zhang, Zunzhen, McMurray, Cynthia T., Liu, Yuan

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An infrared spectral biomarker accurately predicts neurodegenerative disease class in the absence of overt symptoms von Lovergne, Lila, Ghosh, Dhruba, Schuck, Renaud, Polyzos, Aris A., Chen, Andrew D., Martin, Michael C., Barnard, Edward S., Brown, James B., McMurray, Cynthia T.

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Hijacking of the mismatch repair system to cause CAG expansion and cell death in neurodegenerative disease von McMurray, Cynthia T.

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Conformational trapping of Mismatch Recognition Complex MSH2/MSH3 on repair-resistant DNA loops von Lang, Walter H, Coats, Julie E, Majka, Jerzy, Hura, Greg L, Lin, Yuyen, Rasnik, Ivan, McMurray, Cynthia T

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Mutant Huntingtin Impairs Axonal Trafficking in Mammalian Neurons In Vivo and In Vitro von Trushina, Eugenia, Dyer, Roy B, Badger, 2nd, John D, Ure, Daren, Eide, Lars, Tran, David D, Vrieze, Brent T, Legendre-Guillemin, Valerie, McPherson, Peter S, Mandavilli, Bhaskar S, Van Houten, Bennett, Zeitlin, Scott, McNiven, Mark, Aebersold, Ruedi, Hayden, Michael, Parisi, Joseph E, Seeberg, Erling, Dragatsis, Ioannis, Doyle, Kelly, Bender, Anna, Chacko, Celin, McMurray, Cynthia T

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(CAG)n-hairpin DNA binds to Msh2–Msh3 and changes properties of mismatch recognition von Owen, Barbara A L, Yang, Zungyoon, Lai, Maoyi, Gajek, Maciez, Badger, John D, Hayes, Jeffrey J, Edelmann, Winfried, Kucherlapati, Raju, Wilson, Teresa M, McMurray, Cynthia T

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Retinoic acid-induced differentiation increases the rate of oxygen consumption and enhances the spare respiratory capacity of mitochondria in SH-SY5Y cells von Xun, Zhiyin, Lee, Do-Yup, Lim, James, Canaria, Christie A., Barnebey, Adam, Yanonne, Steven M., McMurray, Cynthia T.

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The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair von HOPFNER, Karl-Peter, CRAIG, Lisa, CARNEY, James P, PETRINI, John H. J, TAINER, John A, MONCALIAN, Gabriel, ZINKEL, Robert A, USUI, Takehiko, OWEN, Barbara A. L, KARCHER, Annette, HENDERSON, Brendan, BODMER, Jean-Luc, MCMURRAY, Cynthia T

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Distinct pools of non-glycolytic substrates differentiate brain regions and prime region-specific responses of mitochondria von Lee, Do Yup, Xun, Zhiyin, Platt, Virginia, Budworth, Helen, Canaria, Christie A, McMurray, Cynthia T

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DNA Secondary Structure: A Common and Causative Factor for Expansion in Human Disease von McMurray, Cynthia T.

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A Brief History of Triplet Repeat Diseases von Budworth, Helen, McMurray, Cynthia T.

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Nuclease-Deficient FEN-1 Blocks Rad51/BRCA1-Mediated Repair and Causes Trinucleotide Repeat Instability von Spiro, Craig, McMurray, Cynthia T.

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