VEGF Receptor Signaling in Tumor Angiogenesis von McMahon, Gerald

Volltext

ErbB activation signatures as potential biomarkers for anti-ErbB3 treatment in HNSCC von Alvarado, Diego, Ligon, Gwenda F, Lillquist, Jay S, Seibel, Scott B, Wallweber, Gerald, Neumeister, Veronique M, Rimm, David L, McMahon, Gerald, LaVallee, Theresa M

Volltext

Inhibition of platelet-derived growth factor signaling attenuates pulmonary fibrosis von Abdollahi, Amir, Li, Minglun, Ping, Gong, Plathow, Christian, Domhan, Sophie, Kiessling, Fabian, Lee, Leslie B, McMahon, Gerald, Gröne, Hermann-Josef, Lipson, Kenneth E, Huber, Peter E

Volltext

PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments von Tanjoni, Isabelle, Walsh, Colin, Uryu, Sean, Tomar, Alok, Nam, Ju-Ock, Mielgo, Ainhoa, Lim, Ssang-Taek, Liang, Congxin, Koenig, Marcel, Patel, Neela, Kwok, Cheni, McMahon, Gerald, Stupack, Dwayne G., Schlaepfer, David D.

Volltext

Oral delivery of PND-1186 FAK inhibitor decreases tumor growth and spontaneous breast to lung metastasis in pre-clinical models von Walsh, Colin, Tanjoni, Isabelle, Uryu, Sean, Tomar, Alok, Nam, Ju-Ock, Luo, Hong, Phillips, Angelica, Patel, Neela, Kwok, Cheni, McMahon, Gerald, Stupack, Dwayne G., Schlaepfer, David D.

Volltext

Phase I Dose-Escalating Study of SU11654, a Small Molecule Receptor Tyrosine Kinase Inhibitor, in Dogs with Spontaneous Malignancies von LONDON, Cheryl A, HANNAH, Alison L, MENDEL, Dirk B, MCMAHON, Gerald, CHERRINGTON, Julie M, ZADOVOSKAYA, Regina, CHIEN, May B, KOLLIAS-BAKER, Cynthia, ROSENBERG, Mona, DOWNING, Sue, POST, Gerald, BOUCHER, Joseph, SHENOY, Narmada

Volltext

SU5416 and SU5614 inhibit kinase activity of wild-type and mutant FLT3 receptor tyrosine kinase von Yee, Kevin W.H., O'Farrell, Anne Marie, Smolich, Beverly D., Cherrington, Julie M., McMahon, Gerald, Wait, Cecily L., McGreevey, Laura S., Griffith, Diana J., Heinrich, Michael C.

Volltext

Design, Synthesis, and Evaluations of Substituted 3-[(3- or 4-Carboxyethylpyrrol-2-yl)methylidenyl]indolin-2-ones as Inhibitors of VEGF, FGF, and PDGF Receptor Tyrosine Kinases von Sun, Li, Tran, Ngoc, Liang, Congxin, Tang, Flora, Rice, Audie, Schreck, Randall, Waltz, Kara, Shawver, Laura K, McMahon, Gerald, Tang, Cho

Volltext

Induction of VEGF in perivascular cells defines a potential paracrine mechanism for endothelial cell survival von Reinmuth, Niels, Liu, Wenbiao, Jung, Young D., Ahmad, Syed A., Shaheen, Raymond M., Fan, Fan, Bucana, Corazon D., McMahon, Gerald, Gallick, Gary E., Ellis, Lee M.

Volltext

Differential Activation of Peroxisome Proliferator-activated Receptors by Eicosanoids (∗) von Yu, Ker, Bayona, William, Kallen, Caleb B., Harding, Heather P., Ravera, Christina P., McMahon, Gerald, Brown, Myles, Lazar, Mitchell A.

Volltext

Potent and selective inhibitors of the Met [hepatocyte growth factor/scatter factor (HGF/SF) receptor] tyrosine kinase block HGF/SF-induced tumor cell growth and invasion von Wang, Xueyan, Le, Phuong, Liang, Congxin, Chan, Julie, Kiewlich, David, Miller, Todd, Harris, Dave, Sun, Li, Rice, Audie, Vasile, Stefan, Blake, Robert A, Howlett, Anthony R, Patel, Neela, McMahon, Gerald, Lipson, Kenneth E

Volltext

FGF10 is an inducer and Pax6 a competence factor for lacrimal gland development von Makarenkova, H P, Ito, M, Govindarajan, V, Faber, S C, Sun, L, McMahon, G, Overbeek, P A, Lang, R A

Volltext

Inhibition of constitutively active forms of mutant kit by multitargeted indolinone tyrosine kinase inhibitors von Liao, Albert T., Chien, May B., Shenoy, Narmada, Mendel, Dirk B., McMahon, Gerald, Cherrington, Julie M., London, Cheryl A.

Volltext

Troglitazone induces a rapid drop of mitochondrial membrane potential in liver HepG2 cells von Bova, Michael P., Tam, Danny, McMahon, Gerald, Mattson, Matthew N.

Volltext

Tyrphostins. 5. Potent Inhibitors of Platelet-Derived Growth Factor Receptor Tyrosine Kinase:  Structure−Activity Relationships in Quinoxalines, Quinolines, and Indole Tyrphostins... von Gazit, Aviv, App, Harald, McMahon, Gerald, Chen, Jefferey, Levitzki, Alexander, Bohmer, Frank D

Volltext

Structure-Based design and discovery of novel inhibitors of protein tyrosine phosphatases von Huang, Ping, Ramphal, John, Wei, James, Liang, Congxin, Jallal, Bahija, McMahon, Gerald, Tang, Cho

Volltext

Antitumor Properties of an IgG2-Enhanced Next-Generation MET Monoclonal Antibody That Degrades Wild-Type and Mutant MET Receptors von Yang, Yan, Mandiyan, Sreekala, Robinson, Brett S, McMahon, Gerald

Volltext

KTN0158, a Humanized Anti-KIT Monoclonal Antibody, Demonstrates Biologic Activity against both Normal and Malignant Canine Mast Cells von London, Cheryl A, Gardner, Heather L, Rippy, Sarah, Post, Gerald, La Perle, Krista, Crew, Linda, Lopresti-Morrow, Lori, Garton, Andrew J, McMahon, Gerald, LaVallee, Theresa M, Gedrich, Richard

Volltext

Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis von Hanahan, Douglas, Bergers, Gabriele, Brekken, Rolf, McMahon, Gerald, Vu, Thiennu H, Itoh, Takeshi, Tamaki, Kazuhiko, Tanzawa, Kazuhiko, Thorpe, Philip, Itohara, Shigeyoshi, Werb, Zena

Volltext

Abstract 3835: An anti-MET IgG2 monoclonal antibody degrades both wild-type and exon 14 mutant MET receptor tyrosine kinase through a novel exon 14-independent mechanism and inhibi... von Robinson, Brett S., Mandiyan, Sreekala, McMahon, Gerald, Yang, Yan

Volltext