Gaucher Disease Glucocerebrosidase and α-Synuclein Form a Bidirectional Pathogenic Loop in Synucleinopathies von Mazzulli, Joseph R., Xu, You-Hai, Sun, Ying, Knight, Adam L., McLean, Pamela J., Caldwell, Guy A., Sidransky, Ellen, Grabowski, Gregory A., Krainc, Dimitri

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α-Synuclein Multimers Cluster Synaptic Vesicles and Attenuate Recycling von Wang, Lina, Das, Utpal, Scott, David A., Tang, Yong, McLean, Pamela J., Roy, Subhojit

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Protein degradation pathways in Parkinson’s disease: curse or blessing von Ebrahimi-Fakhari, Darius, Wahlster, Lara, McLean, Pamela J.

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Cellular models of alpha‐synuclein toxicity and aggregation von Delenclos, Marion, Burgess, Jeremy D., Lamprokostopoulou, Agaristi, Outeiro, Tiago F., Vekrellis, Kostas, McLean, Pamela J.

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Exosomal cell-to-cell transmission of alpha synuclein oligomers von Danzer, Karin M, Kranich, Lisa R, Ruf, Wolfgang P, Cagsal-Getkin, Ozge, Winslow, Ashley R, Zhu, Liya, Vanderburg, Charles R, McLean, Pamela J

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Alpha-synuclein-induced mitochondrial dysfunction is mediated via a sirtuin 3-dependent pathway von Park, Jae-Hyeon, Burgess, Jeremy D., Faroqi, Ayman H., DeMeo, Natasha N., Fiesel, Fabienne C., Springer, Wolfdieter, Delenclos, Marion, McLean, Pamela J.

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Impaired endo-lysosomal membrane integrity accelerates the seeding progression of α-synuclein aggregates von Jiang, Peizhou, Gan, Ming, Yen, Shu-Hui, McLean, Pamela J., Dickson, Dennis W.

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Chaperones in Neurodegeneration von Lindberg, Iris, Shorter, James, Wiseman, R Luke, Chiti, Fabrizio, Dickey, Chad A, McLean, Pamela J

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Optimizing SH-SY5Y cell culture: exploring the beneficial effects of an alternative media supplement on cell proliferation and viability von Kaya, Zeynep Bengisu, Santiago-Padilla, Valeria, Lim, Melina, Boschen, Suelen L., Atilla, Pergin, McLean, Pamela J.

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CRISPR/Cas9 editing of APP C-terminus attenuates β-cleavage and promotes α-cleavage von Sun, Jichao, Carlson-Stevermer, Jared, Das, Utpal, Shen, Minjie, Delenclos, Marion, Snead, Amanda M., Koo, So Yeon, Wang, Lina, Qiao, Dianhua, Loi, Jonathan, Petersen, Andrew J., Stockton, Michael, Bhattacharyya, Anita, Jones, Mathew V., Zhao, Xinyu, McLean, Pamela J., Sproul, Andrew A., Saha, Krishanu, Roy, Subhojit

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Formation of toxic oligomeric alpha-synuclein species in living cells von Outeiro, Tiago Fleming, Putcha, Preeti, Tetzlaff, Julie E, Spoelgen, Robert, Koker, Mirjam, Carvalho, Filipe, Hyman, Bradley T, McLean, Pamela J

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Role of gut microbiota in regulating gastrointestinal dysfunction and motor symptoms in a mouse model of Parkinson's disease von Bhattarai, Yogesh, Si, Jie, Pu, Meng, Ross, Owen A., McLean, Pamela J., Till, Lisa, Moor, William, Grover, Madhusudan, Kandimalla, Karunya K., Margolis, Kara G., Farrugia, Gianrico, Kashyap, Purna C.

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Investigation of Endocytic Pathways for the Internalization of Exosome-Associated Oligomeric Alpha-Synuclein von Delenclos, Marion, Trendafilova, Teodora, Mahesh, Divya, Baine, Ann M, Moussaud, Simon, Yan, Irene K, Patel, Tushar, McLean, Pamela J

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Ubiquitinylation of α-synuclein by carboxyl terminus Hsp70-interacting protein (CHIP) is regulated by Bcl-2-associated athanogene 5 (BAG5) von Kalia, Lorraine V, Kalia, Suneil K, Chau, Hien, Lozano, Andres M, Hyman, Bradley T, McLean, Pamela J

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Dendritic Spine Abnormalities in Amyloid Precursor Protein Transgenic Mice Demonstrated by Gene Transfer and Intravital Multiphoton Microscopy von Spires, Tara L, Meyer-Luehmann, Melanie, Stern, Edward A, McLean, Pamela J, Skoch, Jesse, Nguyen, Paul T, Bacskai, Brian J, Hyman, Bradley T

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Molecular Chaperones and Co-Chaperones in Parkinson Disease von Dimant, Hemi, Ebrahimi-Fakhari, Darius, McLean, Pamela J.

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Post‐inflammatory administration of N‐acetylcysteine reduces inflammation and alters receptor levels in a cellular model of Parkinson's disease von Kaya, Zeynep Bengisu, Karakoc, Elif, McLean, Pamela J., Saka, Esen, Atilla, Pergin

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Alpha-synuclein's degradation in vivo: Opening a new (cranial) window on the roles of degradation pathways in Parkinson disease von Ebrahimi-Fakhari, Darius, McLean, Pamela J., Unni, Vivek K.

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In Vivo Protein Complementation Demonstrates Presynaptic α-Synuclein Oligomerization and Age-Dependent Accumulation of 8–16-mer Oligomer Species von Kiechle, Martin, von Einem, Bjoern, Höfs, Lennart, Voehringer, Patrizia, Grozdanov, Veselin, Markx, Daniel, Parlato, Rosanna, Wiesner, Diana, Mayer, Benjamin, Sakk, Olena, Baumann, Bernd, Lukassen, Soeren, Liss, Birgit, Ekici, Arif B., Ludolph, Albert C., Walther, Paul, Ferger, Boris, McLean, Pamela J., Falkenburger, Björn H., Weishaupt, Jochen H., Danzer, Karin M.

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Chronic treatment with novel small molecule Hsp90 inhibitors rescues striatal dopamine levels but not α-synuclein-induced neuronal cell loss von McFarland, Nikolaus R, Dimant, Hemi, Kibuuka, Laura, Ebrahimi-Fakhari, Darius, Desjardins, Cody A, Danzer, Karin M, Danzer, Michael, Fan, Zhanyun, Schwarzschild, Michael A, Hirst, Warren, McLean, Pamela J

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