Emollient enhancement of the skin barrier from birth offers effective atopic dermatitis prevention von Simpson, Eric L., MD, MCR, Chalmers, Joanne R., PhD, Hanifin, Jon M., MD, Thomas, Kim S., PhD, Cork, Michael J., PhD, FRCP, McLean, W.H. Irwin, FRSE, FMedSci, Brown, Sara J., MRCP, MD, Chen, Zunqiu, MS, Chen, Yiyi, PhD, Williams, Hywel C., DSc, FMedSci

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One Remarkable Molecule: Filaggrin von Brown, Sara J., Irwin McLean, W.H.

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Cytokine Tuning of Intestinal Epithelial Function von Andrews, Caroline, McLean, Mairi H, Durum, Scott K

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Levels of filaggrin degradation products are influenced by both filaggrin genotype and atopic dermatitis severity von Kezic, S., O’Regan, G. M., Yau, N., Sandilands, A., Chen, H., Campbell, L. E., Kroboth, K., Watson, R., Rowland, M., Irwin McLean, W. H., Irvine, A. D.

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Atopic dermatitis increases the effect of exposure to peanut antigen in dust on peanut sensitization and likely peanut allergy von Brough, Helen A., MSc, FRCPCH, Liu, Andrew H., MD, Sicherer, Scott, MD, Makinson, Kerry, MSc, Douiri, Abdel, PhD, Brown, Sara J., MD, Stephens, Alick C., PhD, Irwin McLean, W.H., PhD, DSc, FRSE, FMedSci, Turcanu, Victor, PhD, Wood, Robert A., MD, Jones, Stacie M., MD, Burks, Wesley, MD, Dawson, Peter, PhD, Stablein, Donald, PhD, Sampson, Hugh, MD, Lack, Gideon, MD

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Skin microbiome before development of atopic dermatitis: Early colonization with commensal staphylococci at 2 months is associated with a lower risk of atopic dermatitis at 1 year... von Kennedy, Elizabeth A., BS, Connolly, Jennifer, MSc, Hourihane, Jonathan O'B., DM, Fallon, Padraic G., PhD, McLean, W.H. Irwin, DSc, FRS, Murray, Deirdre, PhD, Jo, Jay-Hyun, PhD, Segre, Julia A., PhD, Kong, Heidi H., MD, MHSc, Irvine, Alan D., MD, DSc

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Atopic dermatitis is associated with an increased risk for rheumatoid arthritis and inflammatory bowel disease, and a decreased risk for type 1 diabetes von Schmitt, Jochen, MD, MPH, Schwarz, Kristin, MSc, Baurecht, Hansjörg, MSc, Hotze, Melanie, MSc, Fölster-Holst, Regina, MD, Rodríguez, Elke, PhD, Lee, Young A.E., MD, Franke, Andre, PhD, Degenhardt, Frauke, MSc, Lieb, Wolfgang, PhD, Gieger, Christian, PhD, Kabesch, Michael, MD, Nöthen, Markus M., MD, Irvine, Alan D., MD, McLean, W.H. Irwin, PhD, Deckert, Stefanie, MPH, Stephan, Victoria, Schwarz, Peter, MD, Aringer, Martin, MD, Novak, Natalija, MD, Weidinger, Stephan, MD, MaHM

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Clumping Factor B Promotes Adherence of Staphylococcus aureus to Corneocytes in Atopic Dermatitis von Fleury, Orla M, McAleer, Maeve A, Feuillie, Cécile, Formosa-Dague, Cécile, Sansevere, Emily, Bennett, Désirée E, Towell, Aisling M, McLean, W H Irwin, Kezic, Sanja, Robinson, D Ashley, Fallon, Padraic G, Foster, Timothy J, Dufrêne, Yves F, Irvine, Alan D, Geoghegan, Joan A

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Filaggrin in the frontline: role in skin barrier function and disease von Sandilands, Aileen, Sutherland, Calum, Irvine, Alan D, McLean, W.H. Irwin

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Atopic Dermatitis and Disease Severity Are the Main Risk Factors for Food Sensitization in Exclusively Breastfed Infants von Flohr, Carsten, Perkin, Michael, Logan, Kirsty, Marrs, Tom, Radulovic, Suzana, Campbell, Linda E., MacCallum, Stephanie F., Irwin McLean, W.H., Lack, Gideon

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Does the microbiota play a role in the pathogenesis of autoimmune diseases? von McLean, Mairi H, Dieguez, Dario, Miller, Lindsey M, Young, Howard A

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The persistence of atopic dermatitis and filaggrin ( FLG ) mutations in a US longitudinal cohort von Margolis, David J., MD, PhD, Apter, Andrea J., MD, MSc, Gupta, Jayanta, MD, PhD, Hoffstad, Ole, MS, Papadopoulos, Maryte, BA, Campbell, Linda E., BA, Sandilands, Aileen, PhD, McLean, W.H. Irwin, PhD, DSc, Rebbeck, Tim R., PhD, Mitra, Nandita, PhD

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Insect symbionts in food webs von McLean, Ailsa H. C., Parker, Benjamin J., Hrček, Jan, Henry, Lee M., Godfray, H. Charles J.

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Variation in intrinsic resistance of pea aphids to parasitoid wasps: A transcriptomic basis von McLean, Ailsa H C, Parker, Benjamin J

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Filaggrin Mutations Associated with Skin and Allergic Diseases von Irvine, Alan D, McLean, W.H. Irwin, Leung, Donald Y.M

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A lack of premature termination codon read-through efficacy of PTC124 (Ataluren) in a diverse array of reporter assays von McElroy, Stuart P, Nomura, Toshifumi, Torrie, Leah S, Warbrick, Emma, Gartner, Ulrike, Wood, Gavin, McLean, W H Irwin

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Keratin disorders: from gene to therapy von IRWIN MCLEAN, W. H, TARA MOORE, C. B

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Severe dermatitis, multiple allergies, and metabolic wasting syndrome caused by a novel mutation in the N-terminal plakin domain of desmoplakin von McAleer, Maeve A., MB, MRCP, Pohler, Elizabeth, PhD, Smith, Frances J.D., PhD, Wilson, Neil J., MSc, Cole, Christian, PhD, MacGowan, Stuart, PhD, Koetsier, Jennifer L., BS, Godsel, Lisa M., PhD, Harmon, Robert M., PhD, Gruber, Robert, MD, Crumrine, Debra, BS, Elias, Peter M., MD, McDermott, Michael, FRCPath, Butler, Karina, FRCPI, Broderick, Annemarie, MRCPI, Sarig, Ofer, PhD, Sprecher, Eli, MD, PhD, Green, Kathleen J., PhD, McLean, W.H. Irwin, PhD, DSc, FRS, FRSE, FMedSci, Irvine, Alan D., MD

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Skin barrier dysfunction measured by transepidermal water loss at 2 days and 2 months predates and predicts atopic dermatitis at 1 year von Kelleher, Maeve, MB, Dunn-Galvin, Audrey, PhD, Hourihane, Jonathan O'B., DM, Murray, Deirdre, MD, Campbell, Linda E., BSc, McLean, W.H. Irwin, DSc, FRS, Irvine, Alan D., MD

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Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis von Cole, Christian, PhD, Kroboth, Karin, MSc, Schurch, Nicholas J., PhD, Sandilands, Aileen, PhD, Sherstnev, Alexander, PhD, O'Regan, Grainne M., MRCPI, Watson, Rosemarie M., MD, Irwin McLean, W.H., DSc, Barton, Geoffrey J., PhD, Irvine, Alan D., MD, Brown, Sara J., MD

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