Targeting Mitochondria-Derived Reactive Oxygen Species to Reduce Epithelial Barrier Dysfunction and Colitis von Wang, Arthur, Keita, Åsa V, Phan, Van, McKay, Catherine M, Schoultz, Ida, Lee, Joshua, Murphy, Michael P, Fernando, Maria, Ronaghan, Natalie, Balce, Dale, Yates, Robin, Dicay, Michael, Beck, Paul L, MacNaughton, Wallace K, Söderholm, Johan D, McKay, Derek M

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Activation of neuronal P2X7 receptor–pannexin-1 mediates death of enteric neurons during colitis von Gulbransen, Brian D, Bashashati, Mohammad, Hirota, Simon A, Gui, Xianyong, Roberts, Jane A, MacDonald, Justin A, Muruve, Daniel A, McKay, Derek M, Beck, Paul L, Mawe, Gary M, Thompson, Roger J, Sharkey, Keith A

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In Vitro-Derived Alternatively Activated Macrophages Reduce Colonic Inflammation in Mice von Hunter, Meaghan M, Wang, Arthur, Parhar, Kuljit S, Johnston, Michael J.G, Van Rooijen, Nico, Beck, Paul L, McKay, Derek M

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Reduced intestinal epithelial mitochondrial function enhances in vitro interleukin-8 production in response to commensal Escherichia coli von Saxena, Alpana, Lopes, Fernando, McKay, Derek M.

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Modulation of the immune response by helminths: a role for serotonin? von Wang, Susan J, Sharkey, Keith A, McKay, Derek M

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Enhanced translocation of bacteria across metabolically stressed epithelia is reduced by butyrate von Lewis, Kimberley, Lutgendorff, Femke, Phan, Van, Söderholm, Johan D., Sherman, Philip M., McKay, Derek M.

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Enteric tuft cells coordinate timely expulsion of the tapeworm Hymenolepis diminuta from the murine host by coordinating local but not systemic immunity von Rajeev, Sruthi, Li, ShuHua, Leon-Coria, Aralia, Wang, Arthur, Kraemer, Lucas, Wang, Susan Joanne, Boim, Annaliese, Flannigan, Kyle, Shute, Adam, Baggio, Cristiane H, Callejas, Blanca E, MacNaughton, Wallace K, Finney, Constance A M, McKay, Derek M

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Butyrate enhances antibacterial effects while suppressing other features of alternative activation in IL-4-induced macrophages von Fernando, Maria R, Saxena, Alpana, Reyes, José-Luis, McKay, Derek M

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Absence of the NOD2 protein renders epithelia more susceptible to barrier dysfunction due to mitochondrial dysfunction von Saxena, Alpana, Lopes, Fernando, Poon, Karen K H, McKay, Derek M

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Itch induced by peripheral mu opioid receptors is dependent on TRPV1-expressing neurons and alleviated by channel activation von Melo, Helvira, Basso, Lilian, Iftinca, Mircea, MacNaughton, Wallace K., Hollenberg, Morley D., McKay, Derek M., Altier, Christophe

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Aspirin-triggered lipoxin enhances macrophage phagocytosis of bacteria while inhibiting inflammatory cytokine production von Prescott, David, McKay, Derek M

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IL-22 Restrains Tapeworm-Mediated Protection against Experimental Colitis via Regulation of IL-25 Expression von Reyes, José L, Fernando, Maria R, Lopes, Fernando, Leung, Gabriella, Mancini, Nicole L, Matisz, Chelsea E, Wang, Arthur, McKay, Derek M

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P-selectin-mediated monocyte-cerebral endothelium adhesive interactions link peripheral organ inflammation to sickness behaviors von D'Mello, Charlotte, Riazi, Kiarash, Le, Tai, Stevens, Katarzyna M, Wang, Arthur, McKay, Derek M, Pittman, Quentin J, Swain, Mark G

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A simple, cost-effective method for generating murine colonic 3D enteroids and 2D monolayers for studies of primary epithelial cell function von Fernando, Elizabeth H, Dicay, Michael, Stahl, Martin, Gordon, Marilyn H, Vegso, Andrew, Baggio, Cristiane, Alston, Laurie, Lopes, Fernando, Baker, Kristi, Hirota, Simon, McKay, Derek M, Vallance, Bruce, MacNaughton, Wallace K

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Cooperation between host immunity and the gut bacteria is essential for helminth-evoked suppression of colitis von Shute, Adam, Callejas, Blanca E., Li, ShuHua, Wang, Arthur, Jayme, Timothy S., Ohland, Christina, Lewis, Ian A., Layden, Brian T., Buret, Andre G., McKay, Derek M.

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Species dependent impact of helminth-derived antigens on human macrophages infected with Mycobacterium tuberculosis: Direct effect on the innate anti-mycobacterial response von Aira, Naomi, Andersson, Anna-Maria, Singh, Susmita K, McKay, Derek M, Blomgran, Robert

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Impact of experimental colitis on mitochondrial bioenergetics in intestinal epithelial cells von Goudie, Luke, Mancini, Nicole L., Shutt, Timothy E., Holloway, Graham P., Mu, Chunlong, Wang, Arthur, McKay, Derek M., Shearer, Jane

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Cathelicidin-mediated lipopolysaccharide signaling via intracellular TLR4 in colonic epithelial cells evokes CXCL8 production von Holani, Ravi, Babbar, Anshu, Blyth, Graham A. D., Lopes, Fernando, Jijon, Humberto, McKay, Derek M., Hollenberg, Morley D., Cobo, Eduardo R.

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Reduced surface expression of epithelial E-cadherin evoked by interferon-gamma is Fyn kinase-dependent von Smyth, David, Leung, Gabriella, Fernando, Maria, McKay, Derek M

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Macrophage immunotherapy: overcoming impediments to realize promise von Sly, Laura M., McKay, Derek M.

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