Pharmacological Inhibition of the Histone Lysine Demethylase KDM1A Suppresses the Growth of Multiple Acute Myeloid Leukemia Subtypes von McGrath, John P, Williamson, Kaylyn E, Balasubramanian, Srividya, Odate, Shobu, Arora, Shilpi, Hatton, Charlie, Edwards, Thomas M, O'Brien, Thomas, Magnuson, Steven, Stokoe, David, Daniels, Danette L, Bryant, Barbara M, Trojer, Patrick

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Genomic alterations link Rho family of GTPases to the highly invasive phenotype of pancreas cancer von Kimmelman, Alec C, Hezel, Aram F, Aguirre, Andrew J, Zheng, Hongwu, Paik, Ji-hye, Ying, Haoqiang, Chu, Gerald C, Zhang, Jean X, Sahin, Ergun, Yeo, Giminna, Ponugoti, Aditya, Nabioullin, Roustem, Deroo, Scott, Yang, Shenghong, Wang, Xiaoxu, McGrath, John P, Protopopova, Marina, Ivanova, Elena, Zhang, Jianhua, Feng, Bin, Tsao, Ming S, Redston, Mark, Protopopov, Alexei, Xiao, Yonghong, Futreal, P. Andrew, Hahn, William C, Klimstra, David S, Chin, Lynda, DePinho, Ronald A

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Recognition of yeast β-glucan particles triggers immunometabolic signaling required for trained immunity von Horneck Johnston, Cian J.H., Ledwith, Anna E., Lundahl, Mimmi L.E., Charles-Messance, Hugo, Hackett, Emer E., O’Shaughnessy, Simon D., Clegg, Jonah, Prendeville, Hannah, McGrath, John P., Walsh, Aaron M., Case, Sarah, Austen Byrne, Hollie, Gautam, Parth, Dempsey, Elaine, Corr, Sinead C., Sheedy, Frederick J.

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Merkel cell polyomavirus activates LSD1-mediated blockade of non-canonical BAF to regulate transformation and tumorigenesis von Park, Donglim Esther, Cheng, Jingwei, McGrath, John P., Lim, Matthew Y., Cushman, Camille, Swanson, Selene K., Tillgren, Michelle L., Paulo, Joao A., Gokhale, Prafulla C., Florens, Laurence, Washburn, Michael P., Trojer, Patrick, DeCaprio, James A.

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Author Correction: Merkel cell polyomavirus activates LSD1-mediated blockade of non-canonical BAF to regulate transformation and tumorigenesis von Park, Donglim Esther, Cheng, Jingwei, McGrath, John P., Lim, Matthew Y., Cushman, Camille, Swanson, Selene K., Tillgren, Michelle L., Paulo, Joao A., Gokhale, Prafulla C., Florens, Laurence, Washburn, Michael P., Trojer, Patrick, DeCaprio, James A.

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Design and Synthesis of Styrenylcyclopropylamine LSD1 Inhibitors von Gehling, Victor S, McGrath, John P, Duplessis, Martin, Khanna, Avinash, Brucelle, Francois, Vaswani, Rishi G, Côté, Alexandre, Stuckey, Jacob, Watson, Venita, Cummings, Richard T, Balasubramanian, Srividya, Iyer, Priyadarshini, Sawant, Priyanka, Good, Andrew C, Albrecht, Brian K, Harmange, Jean-Christophe, Audia, James E, Bellon, Steven F, Trojer, Patrick, Levell, Julian R

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Comparative biochemical properties of normal and activated human ras p21 protein von McGrath, John P, Capon, Daniel J, Goeddel, David V, Levinson, Arthur D

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The yeast STE6 gene encodes a homologue of the mammalian multidrug resistance P-glycoprotein von McGrath, John P, Varshavsky, Alexander

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The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme von Jentsch, S, McGrath, J.P, Varshavsky, A

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An Essential Yeast Gene Encoding a Homolog of Ubiquitin-activating Enzyme von Dohmen, R J, Stappen, R, McGrath, J P, Forrová, H, Kolarov, J, Goffeau, A, Varshavsky, A

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Evaluation of the Erythroid Regenerative Response in Two Different Models of Experimentally Induced Iron Deficiency Anemia von Burkhard, Mary Jo, Brown, Diane E., McGrath, John P., Meador, Vince P., Mayle, Douglas A., Keaton, M. Joni, Hoffman, Wherly P., Zimmermann, John L., Abbott, David L., Sun, Steven C.

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Structure and organization of the human Ki- ras proto-oncogene and a related processed pseudogene von McGrath, John P, Capon, Daniel J, Smith, Douglas H, Chen, Ellson Y, Seeburg, Peter H, Goeddel, David V, Levinson, Arthur D

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Abstract 2126: Therapeutic potential of CPI-0209 von Wu, Rentian, Zhao, Feng, Keller, Patricia J., Mertz, Jennifer A., McGrath, John P., Bryant, Barbara, Conery, Andrew R., Sun, Kaiming, Wang, Jing, Trojer, Patrick

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The yeast cell cycle gene CDC34 encodes a ubiquitin-conjugating enzyme von Goebl, M.G, Yochem, J, Jentsch, S, McGrath, J.P, Varshavsky, A, Byers, B

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LSD1 Inhibitor CPI-482 Shows Efficacy and Prolongs Survival in Mouse Models of AML and Post-MPN AML in the Context of Constitutive JAK-STAT Pathway Activation von Rampal, Raajit K., McGrath, John P., Krishnan, Aishwarya, Li, Bing, Xiao, Wenbin, Nikom, David, Wang, Jing, Levine, Ross L., Trojer, Patrick

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Assessment of Hemolytic and Hemorrhagic Anemias in Preclinical Safety Assessment Studies von Mcgrath, John P.

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Highly purified recombinant adeno-associated virus vectors are biologically active and free of detectable helper and wild-type viruses von Clark, K R, Liu, X, McGrath, J P, Johnson, P R

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Activation of Ki-ras2 gene in human colon and lung carcinomas by two different point mutations von Capon, Daniel J., Seeburg, Peter H., McGrath, John P., Hayflick, Joel S., Edman, Ursula, Levinson, Arthur D., Goeddel, David V.

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Abstract 3714: Characterization of a selective focal adhesion kinase (FAK) inhibitor in a panel of glioblastoma cell lines identify rational drug-drug combination strategies von Chen, Shujuan, Johnson, Natalie, Auger, Kurt R., Xiao, Yonghong, Ying, Haoqiang, Marszalek, Joseph, Middleton, Richard, Andersen, Jannik N., McGrath, John P., Chin, Lynda

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Search for the Bonhomme Richard Using Computer Modeling and Submarine Technologies von Ryan, Melissa S., McGrath, John P.

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