The use of extrapolation based on modeling and simulation to support high‐dose regimens of ceftaroline fosamil in pediatric patients with complicated skin and soft‐tissue infection... von Chan, Phylinda L.S., McFadyen, Lynn, Quaye, Andrea, Leister‐Tebbe, Heidi, Hendrick, Victoria M., Hammond, Jennifer, Raber, Susan

Volltext

A Retrospective Analysis of Probability of Target Attainment in Community-Acquired Pneumonia: Ceftaroline Fosamil Versus Comparators von Cristinacce, Andrew, Wright, James G., Stone, Gregory G., Hammond, Jennifer, McFadyen, Lynn, Raber, Susan

Volltext

A population pharmacokinetic meta‐analysis of maraviroc in healthy volunteers and asymptomatic HIV‐infected subjects von Chan, Phylinda L. S., Weatherley, Barry, McFadyen, Lynn

Volltext

A receptor theory‐based semimechanistic PD model for the CCR5 noncompetitive antagonist maraviroc von Jacqmin, Philippe, McFadyen, Lynn, Wade, Janet R.

Volltext

Population Pharmacokinetic Modeling for Ceftazidime‐Avibactam Renal Dose Adjustments in Pediatric Patients 3 months and Older von Franzese, Richard, Riccobene, Todd, Carrothers, Timothy, Vourvahis, Manoli, Winter, Erica, Lovern, Mark, McFadyen, Lynn

Volltext

Translational pharmacokinetic–pharmacodynamic modelling; application to cardiovascular safety data for PF‐00821385, a novel HIV agent von Langdon, Grant, Davis, John D., McFadyen, Lynn M., Dewhurst, Mark, Brunton, Neil S., Rawal, Jaiessh K., Van der Graaf, Piet H., Benson, Neil

Volltext

Dose selection for aztreonam-avibactam, including adjustments for renal impairment, for Phase IIa and Phase III evaluation von Das, Shampa, Riccobene, Todd, Carrothers, Timothy J., Wright, James G., MacPherson, Merran, Cristinacce, Andrew, McFadyen, Lynn, Xie, Rujia, Luckey, Alison, Raber, Susan

Volltext

Complexity and Diversity of Klebsiella pneumoniae Strains with Extended-Spectrum β-Lactamases Isolated in 1994 and 1996 at a Teaching Hospital in Durban, South Africa von ESSACK, Sabiha Y, HALL, Lucinda M. C, PILLAY, Devadas G, MCFADYEN, Margaret Lynn, LIVERMORE, David M

Volltext

Population Pharmacokinetics of Fosdagrocorat (PF‐04171327), a Dissociated Glucocorticoid Receptor Agonist, in Patients With Rheumatoid Arthritis von Weatherley, Barry, McFadyen, Lynn, Tammara, Brinda

Volltext

Pregabalin Population Pharmacokinetic and Exposure‐Response Analyses for Focal Onset Seizures in Children (4–16 years) and Adults, to Support Dose Recommendations in Children von Chan, Phylinda L. S., Marshall, Scott F., McFadyen, Lynn, Liu, Jing

Volltext

Counting the costs: comparing depot medroxyprogesterone acetate and norethisterone oenanthate utilisation patterns in South Africa von Smit, J, Gray, A, McFadyen, L, Zuma, K

Volltext

Population Pharmacokinetic Modeling and Probability of Pharmacodynamic Target Attainment for Ceftazidime‐Avibactam in Pediatric Patients Aged 3 Months and Older von Franzese, Richard C., McFadyen, Lynn, Watson, Kenny J., Riccobene, Todd, Carrothers, Timothy J., Vourvahis, Manoli, Chan, Phylinda L.S., Raber, Susan, Bradley, John S., Lovern, Mark

Volltext

Clinical relevance of CYP3A5 genotype on maraviroc exposures von Vourvahis, Manoli, McFadyen, Lynn, Heera, Jayvant, Clark, Andrew

Volltext

Population Pharmacokinetics of Rifapentine and Its Primary Desacetyl Metabolite in South African Tuberculosis Patients von LANGDON, Grant, WILKINS, Justin, MCFADYEN, Lynn, MCILLERON, Helen, SMITH, Peter, SIMONSSON, Ulrika S. H

Volltext

Maraviroc modelling strategy: use of early phase 1 data to support a semi‐mechanistic population pharmacokinetic model von Weatherley, Barry, McFadyen, Lynn

Volltext

Population Analysis of Anidulafungin in Infants to Older Adults With Confirmed or Suspected Invasive Candidiasis von Xie, Rujia, McFadyen, Lynn, Raber, Susan, Swanson, Robert, Tawadrous, Margaret, Leister‐Tebbe, Heidi, Cohen‐Wolkowiez, Michael, Benjamin, Daniel K., Liu, Ping

Volltext

Once-daily maraviroc versus tenofovir/emtricitabine each combined with darunavir/ritonavir for initial HIV-1 treatment von Stellbrink, Hans-Jürgen, Le Fevre, Eric, Carr, Andrew, Saag, Michael S, Mukwaya, Geoffrey, Nozza, Silvia, Valluri, Srinivas Rao, Vourvahis, Manoli, Rinehart, Alex R, McFadyen, Lynn, Fichtenbaum, Carl, Clark, Andrew, Craig, Charles, Fang, Annie F, Heera, Jayvant

Volltext

Pharmacokinetics, Safety and Efficacy of Maraviroc in Treatment-experienced Pediatric Patients Infected With CCR5-Tropic HIV-1 von Giaquinto, Carlo, Mawela, Muthuhadini Patience, Chokephaibulkit, Kulkanya, Negra, Marinella Della, Mitha, Ismail Haroon, Fourie, Jan, Fang, Annie, van der Ryst, Elna, Valluri, Srinivas Rao, Vourvahis, Manoli, Zhang-Roper, Rebecca Yanhui, Craig, Charles, McFadyen, Lynn, Clark, Andrew, Heera, Jayvant

Volltext

Pharmacokinetics and safety of maraviroc in neonates von Rosebush, Julia C., Best, Brookie M., Chadwick, Ellen G., Butler, Kevin, Moye, John, Smith, Elizabeth, Bradford, Sarah, Reding, Christina A., Mathiba, Sisinyana R., Hanley, Sherika, Aziz, Mariam, Homans, James, Acosta, Edward P., Murtaugh, William, Vourvahis, Manoli, Mcfadyen, Lynn, Hayward, Katy, Mirochnick, Mark, Samson, Pearl

Volltext

Maraviroc Once-Daily Nucleoside Analog-Sparing Regimen in Treatment-Naive Patients: Randomized, Open-Label Pilot Study von Mills, Anthony, Mildvan, Donna, Podzamczer, Daniel, Fätkenheuer, Gerd, Leal, Manuel, Than, Soe, Valluri, Srinivas R, Craig, Charles, McFadyen, Lynn, Vourvahis, Manoli, Heera, Jayvant, Valdez, Hernan, Rinehart, Alex R, Portsmouth, Simon

Volltext