Discovery of Indoles as Potent and Selective Inhibitors of the Deacetylase SIRT1 von Napper, Andrew D, Hixon, Jeffrey, McDonagh, Thomas, Keavey, Kenneth, Pons, Jean-Francois, Barker, Jonathan, Yau, Wei Tsung, Amouzegh, Patricia, Flegg, Adam, Hamelin, Estelle, Thomas, Russell J, Kates, Michael, Jones, Stephen, Navia, Manuel A, Saunders, Jeffrey O, DiStefano, Peter S, Curtis, Rory

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Inhibition of SIRT1 Catalytic Activity Increases p53 Acetylation but Does Not Alter Cell Survival following DNA Damage von Solomon, Jonathan M., Pasupuleti, Rao, Xu, Lei, McDonagh, Thomas, Curtis, Rory, DiStefano, Peter S., Huber, L. Julie

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Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells von Bordone, Laura, Motta, Maria Carla, Picard, Frederic, Robinson, Ashley, Jhala, Ulupi S, Apfeld, Javier, McDonagh, Thomas, Lemieux, Madeleine, McBurney, Michael, Szilvasi, Akos, Easlon, Erin J, Lin, Su-Ju, Guarente, Leonard

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Substrate-specific Activation of Sirtuins by Resveratrol von Kaeberlein, Matt, McDonagh, Thomas, Heltweg, Birgit, Hixon, Jeffrey, Westman, Eric A., Caldwell, Seth D., Napper, Andrew, Curtis, Rory, DiStefano, Peter S., Fields, Stanley, Bedalov, Antonio, Kennedy, Brian K.

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Energy localization and frequency analysis in the locust ear von Malkin, Robert, McDonagh, Thomas R., Mhatre, Natasha, Scott, Thomas S., Robert, Daniel

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Manipulating drug release from 3D printed dual-drug loaded polypills using challenging polymer compositions von McDonagh, Thomas, Belton, Peter, Qi, Sheng

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Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5 von Mosyak, Lidia, Georgiadis, Katy, Shane, Tania, Svenson, Kristine, Hebert, Tracy, McDonagh, Thomas, Mackie, Stewart, Olland, Stephane, Lin, Laura, Zhong, Xiaotian, Kriz, Ronald, Reifenberg, Erica L., Collins‐Racie, Lisa A., Corcoran, Christopher, Freeman, Bethany, Zollner, Richard, Marvell, Tod, Vera, Matthew, Sum, Phaik‐Eng, Lavallie, Edward R., Stahl, Mark, Somers, William

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An investigation into the effects of geometric scaling and pore structure on drug dose and release of 3D printed solid dosage forms von McDonagh, Thomas, Belton, Peter, Qi, Sheng

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Pharmacology of smac mimetics; chemotype differentiation based on physical association with caspase regulators and cellular transport von Talbott, Randy L., Borzilleri, Robert M., Chaudhry, Charu, Fargnoli, Joseph, Shen, Henry, Fairchild, Craig, Barnhart, Bryan, Ortega, Marie, McDonagh, Thomas E., Vuppugalla, Ragini, Vite, Gregory D., Hunt, John T., Gottardis, Marco, Naglich, Joseph G.

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Correction: Sirt1 Regulates Insulin Secretion by Repressing UCP2 in Pancreatic β Cells von Bordone, Laura, Motta, Maria Carla, Picard, Frederic, Robinson, Ashley, Jhala, Ulupi S, Apfeld, Javier, McDonagh, Thomas, Lemieux, Madeleine, McBurney, Michael, Szilvasi, Akos, Easlon, Erin J, Lin, Su-Ju, Guarente, Leonard

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The 24-hour respiratory quotient predicts energy intake and changes in body mass von Longo, Kenneth A, Charoenthongtrakul, Soratree, Giuliana, Derek J, Govek, Elizabeth K, McDonagh, Thomas, Distefano, Peter S, Geddes, Brad J

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Direct Granule Feeding of Thermal Droplet Deposition 3D Printing of Porous Pharmaceutical Solid Dosage Forms Free of Plasticisers von McDonagh, Thomas, Belton, Peter, Qi, Sheng

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SIRT1 Shows No Substrate Specificity in Vitro von Blander, Gil, Olejnik, Jerzy, Krzymanska-Olejnik, Edyta, McDonagh, Thomas, Haigis, Marcia, Yaffe, Michael B., Guarente, Leonard

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Autocatalytic Cleavage of ADAMTS-4 (Aggrecanase-1) Reveals Multiple Glycosaminoglycan-binding Sites von Flannery, Carl R, Zeng, Weilan, Corcoran, Chris, Collins-Racie, Lisa A, Chockalingam, Priya S, Hebert, Tracy, Mackie, Stewart A, McDonagh, Thomas, Crawford, Tara K, Tomkinson, Kathy N, LaVallie, Edward R, Morris, Elisabeth A

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Effects of porosity on drug release kinetics of swellable and erodible porous pharmaceutical solid dosage forms fabricated by hot melt droplet deposition 3D printing von Zhang, Bin, Nasereddin, Jehad, McDonagh, Thomas, von Zeppelin, Didier, Gleadall, Andy, Alqahtani, Fahad, Bibb, Richard, Belton, Peter, Qi, Sheng

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Assessing infant and maternal readiness for newborn discharge von Jing, Ling, Bethancourt, Casidhe-Nicole, McDonagh, Thomas

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ADAMTS4 Cleaves at the Aggrecanase Site (Glu373-Ala374) and Secondarily at the Matrix Metalloproteinase Site (Asn341-Phe342) in the Aggrecan Interglobular Domain von Westling, Jennifer, Fosang, Amanda J., Last, Karena, Thompson, Vivian P., Tomkinson, Kathy N., Hebert, Tracy, McDonagh, Thomas, Collins-Racie, Lisa A., LaVallie, Edward R., Morris, Elisabeth A., Sandy, John D.

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A custom ÄKTA avant configuration enabling automated parallel protein purification over a range of process scales von Hollander, Cristopher, Walrond, Shana C., Connelly, Christopher, Megson, Lisa, Bove, Elia, McDonagh, Thomas

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New insights into the effects of porosity, pore length, pore shape and pore alignment on drug release from extrusionbased additive manufactured pharmaceuticals von Zhang, Bin, Gleadall, Andy, Belton, Peter, Mcdonagh, Thomas, Bibb, Richard, Qi, Sheng

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New-onset lone maternal atrial fibrillation: A case report von Janjua, Nusrat Batool, Birmani, Suhaib Akhtar, McDonagh, Thomas, Hameed, Abdul, McKernan, Matthew

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