Pan-tumor genomic biomarkers for PD-1 checkpoint blockade-based immunotherapy von Cristescu, Razvan, Mogg, Robin, Ayers, Mark, Albright, Andrew, Murphy, Erin, Yearley, Jennifer, Sher, Xinwei, Liu, Xiao Qiao, Lu, Hongchao, Nebozhyn, Michael, Zhang, Chunsheng, Lunceford, Jared K, Joe, Andrew, Cheng, Jonathan, Webber, Andrea L, Ibrahim, Nageatte, Plimack, Elizabeth R, Ott, Patrick A, Seiwert, Tanguy Y, Ribas, Antoni, McClanahan, Terrill K, Tomassini, Joanne E, Loboda, Andrey, Kaufman, David

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Interleukin-23-Induced Transcription Factor Blimp-1 Promotes Pathogenicity of T Helper 17 Cells von Jain, Renu, Chen, Yi, Kanno, Yuka, Joyce-Shaikh, Barbara, Vahedi, Golnaz, Hirahara, Kiyoshi, Blumenschein, Wendy M., Sukumar, Selvakumar, Haines, Christopher J., Sadekova, Svetlana, McClanahan, Terrill K., McGeachy, Mandy J., O’Shea, John J., Cua, Daniel J.

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IL-33 Induces IL-13-Dependent Cutaneous Fibrosis von Rankin, Andrew L, Mumm, John B, Murphy, Erin, Turner, Scott, Yu, Ni, McClanahan, Terrill K, Bourne, Patricia A, Pierce, Robert H, Kastelein, Rob, Pflanz, Stefan

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Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling von Boniface, Katia, Bak-Jensen, Kristian S, Li, Ying, Blumenschein, Wendy M, McGeachy, Mandy J, McClanahan, Terrill K, McKenzie, Brent S, Kastelein, Robert A, Cua, Daniel J, de Waal Malefyt, René

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Cutting edge: A critical functional role for IL-23 in psoriasis von Tonel, Giulia, Conrad, Curdin, Laggner, Ute, Di Meglio, Paola, Grys, Katarzyna, McClanahan, Terrill K, Blumenschein, Wendy M, Qin, Jian-Zhong, Xin, Hong, Oldham, Elizabeth, Kastelein, Robert, Nickoloff, Brian J, Nestle, Frank O

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IL-27 Blocks RORc Expression to Inhibit Lineage Commitment of Th17 Cells von Diveu, Caroline, McGeachy, Mandy J, Boniface, Katia, Stumhofer, Jason S, Sathe, Manjiri, Joyce-Shaikh, Barbara, Chen, Yi, Tato, Cristina M, McClanahan, Terrill K, de Waal Malefyt, Rene, Hunter, Christopher A, Cua, Daniel J, Kastelein, Robert A

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Interleukin-23-Independent IL-17 Production Regulates Intestinal Epithelial Permeability von Lee, Jacob S., Tato, Cristina M., Joyce-Shaikh, Barbara, Gulen, Muhammet F., Cayatte, Corinne, Chen, Yi, Blumenschein, Wendy M., Judo, Michael, Ayanoglu, Gulesi, McClanahan, Terrill K., Li, Xiaoxia, Cua, Daniel J.

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WSX-1 and Glycoprotein 130 Constitute a Signal-Transducing Receptor for IL-27 von Pflanz, Stefan, Hibbert, Linda, Mattson, Jeanine, Rosales, Rency, Vaisberg, Elena, Bazan, J. Fernando, Phillips, Joseph H, McClanahan, Terrill K, de Waal Malefyt, Rene, Kastelein, Robert A

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Endogenous IL-33 enhances Th2 cytokine production and T-cell responses during allergic airway inflammation von Louten, Jennifer, Rankin, Andrew L, Li, Ying, Murphy, Erin E, Beaumont, Maribel, Moon, Christina, Bourne, Patricia, McClanahan, Terrill K, Pflanz, Stefan, de Waal Malefyt, Rene

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Autoimmune Memory T Helper 17 Cell Function and Expansion Are Dependent on Interleukin-23 von Haines, Christopher J., Chen, Yi, Blumenschein, Wendy M., Jain, Renu, Chang, Charlie, Joyce-Shaikh, Barbara, Porth, Katherine, Boniface, Katia, Mattson, Jeanine, Basham, Beth, Anderton, Stephen M., McClanahan, Terrill K., Sadekova, Svetlana, Cua, Daniel J., McGeachy, Mandy J.

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Multiplexed quantification of proteins and transcripts in single cells von Peterson, Vanessa M, Zhang, Kelvin Xi, Kumar, Namit, Wong, Jerelyn, Li, Lixia, Wilson, Douglas C, Moore, Renee, McClanahan, Terrill K, Sadekova, Svetlana, Klappenbach, Joel A

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IFN-γ-related mRNA profile predicts clinical response to PD-1 blockade von Ayers, Mark, Lunceford, Jared, Nebozhyn, Michael, Murphy, Erin, Loboda, Andrey, Kaufman, David R, Albright, Andrew, Cheng, Jonathan D, Kang, S Peter, Shankaran, Veena, Piha-Paul, Sarina A, Yearley, Jennifer, Seiwert, Tanguy Y, Ribas, Antoni, McClanahan, Terrill K

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LAG3+ Regulatory T Cells Restrain Interleukin-23-Producing CX3CR1+ Gut-Resident Macrophages during Group 3 Innate Lymphoid Cell-Driven Colitis von Bauché, David, Joyce-Shaikh, Barbara, Jain, Renu, Grein, Jeff, Ku, Karin S., Blumenschein, Wendy M., Ganal-Vonarburg, Stephanie C., Wilson, Douglas C., McClanahan, Terrill K., Malefyt, Rene de Waal, Macpherson, Andrew J., Annamalai, Lakshmanan, Yearley, Jennifer H., Cua, Daniel J.

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IL-23 induces spondyloarthropathy by acting on ROR-γt+ CD3+CD4−CD8− entheseal resident T cells von Sherlock, Jonathan P, Joyce-Shaikh, Barbara, Turner, Scott P, Chao, Cheng-Chi, Sathe, Manjiri, Grein, Jeff, Gorman, Daniel M, Bowman, Edward P, McClanahan, Terrill K, Yearley, Jennifer H, Eberl, Gérard, Buckley, Christopher D, Kastelein, Robert A, Pierce, Robert H, LaFace, Drake M, Cua, Daniel J

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T‐cell infiltration and clonality correlate with programmed cell death protein 1 and programmed death‐ligand 1 expression in patients with soft tissue sarcomas von Pollack, Seth M., He, Qianchuan, Yearley, Jennifer H., Emerson, Ryan, Vignali, Marissa, Zhang, Yuzheng, Redman, Mary W., Baker, Kelsey K., Cooper, Sara, Donahue, Bailey, Loggers, Elizabeth T., Cranmer, Lee D., Spraker, Matthew B., Seo, Y. David, Pillarisetty, Venu G., Ricciotti, Robert W., Hoch, Benjamin L., McClanahan, Terrill K., Murphy, Erin, Blumenschein, Wendy M., Townson, Steven M., Benzeno, Sharon, Riddell, Stanley R., Jones, Robin L.

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Clinical improvement in psoriasis with specific targeting of interleukin-23 von Kopp, Tamara, Riedl, Elisabeth, Bangert, Christine, Bowman, Edward P., Greisenegger, Elli, Horowitz, Ann, Kittler, Harald, Blumenschein, Wendy M., McClanahan, Terrill K., Marbury, Thomas, Zachariae, Claus, Xu, Danlin, Hou, Xiaoli Shirley, Mehta, Anish, Zandvliet, Anthe S., Montgomery, Diana, van Aarle, Frank, Khalilieh, Sauzanne

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Transcriptomic Determinants of Response to Pembrolizumab Monotherapy across Solid Tumor Types von Cristescu, Razvan, Nebozhyn, Michael, Zhang, Chunsheng, Albright, Andrew, Kobie, Julie, Huang, Lingkang, Zhao, Qing, Wang, Anran, Ma, Hua, Alexander Cao, Z, Morrissey, Michael, Ribas, Antoni, Grivas, Petros, Cescon, David W, McClanahan, Terrill K, Snyder, Alexandra, Ayers, Mark, Lunceford, Jared, Loboda, Andrey

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The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17–producing effector T helper cells in vivo von McGeachy, Mandy J, Chen, Yi, Tato, Cristina M, Laurence, Arian, Joyce-Shaikh, Barbara, Blumenschein, Wendy M, McClanahan, Terrill K, O'Shea, John J, Cua, Daniel J

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The myeloid receptor PILRβ mediates the balance of inflammatory responses through regulation of IL-27 production von Tato, Cristina M, Joyce-Shaikh, Barbara, Banerjee, Antara, Chen, Yi, Sathe, Manjiri, Ewald, Sarah E, Liu, Man-Ru, Gorman, Daniel, McClanahan, Terrill K, Phillips, Joseph H, Heyworth, Paul G, Cua, Daniel J

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Establishment of engineered cell-based assays mediating LAG3 and PD1 immune suppression enables potency measurement of blocking antibodies and assessment of signal transduction von Bhagwat, Bhagyashree, Cherwinski, Holly, Sathe, Manjiri, Seghezzi, Wolfgang, McClanahan, Terrill K., de Waal Malefyt, Rene, Willingham, Aarron

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