Combination Immune Checkpoint Inhibition: Is First Line Best? von McArthur, Grant A

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The Cell-Cycle Regulator CDK4: An Emerging Therapeutic Target in Melanoma von SHEPPARD, Karen E, MCARTHUR, Grant A

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Targeting Oncogenic Drivers and the Immune System in Melanoma von MCARTHUR, Grant A, RIBAS, Antoni

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Melanoma staging: Evidence‐based changes in the American Joint Committee on Cancer eighth edition cancer staging manual von Gershenwald, Jeffrey E., Scolyer, Richard A., Hess, Kenneth R., Sondak, Vernon K., Long, Georgina V., Ross, Merrick I., Lazar, Alexander J., Faries, Mark B., Kirkwood, John M., McArthur, Grant A., Haydu, Lauren E., Eggermont, Alexander M. M., Flaherty, Keith T., Balch, Charles M., Thompson, John F., Gershenwald, Jeffrey E., Scolyer, Richard A., Atkins, Michael B., Balch, Charles M., Barnhill, Raymond L., Bilimoria, Karl Y., Buzaid, Antonio C., Byrd, David R., Cochran, Alistair J., Eggermont, Alexander M. M., Elder, David E., Faries, Mark B., Flaherty, Keith T., Garbe, Claus, Gardner, Julie M., Gimotty, Phyllis A., Halpern, Allan C., Haydu, Lauren E., Hess, Kenneth R., Johnson, Timothy M., Kirkwood, John M., Lazar, Alexander J., Lee, Anne W. M., Long, Georgina V., McArthur, Grant A., Mihm Jr, Martin C., Prieto, Victor G., Ross, Merrick I., Sober, Arthur J., Sondak, Vernon K., Thompson, John F., Wong, Sandra L., Delman, Keith A., Santinami, Mario, Maurichi, Andrea, Nagore, Eduardo, Faries, Mark B., Thompson, John F., Scolyer, Richard A., McArthur, Grant A., Gyorki, David E., Henderson, Michael, Stratigos, Alexander J., Gogas, Helen, Gershenwald, Jeffrey E., Haydu, Lauren E., Rossi, Carlo Riccardo, Sommariva, Antonio

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Inhibition of RNA Polymerase I as a Therapeutic Strategy to Promote Cancer-Specific Activation of p53 von Bywater, Megan J., Poortinga, Gretchen, Sanij, Elaine, Hein, Nadine, Peck, Abigail, Cullinane, Carleen, Wall, Meaghan, Cluse, Leonie, Drygin, Denis, Anderes, Kenna, Huser, Nanni, Proffitt, Chris, Bliesath, Joshua, Haddach, Mustapha, Schwaebe, Michael K., Ryckman, David M., Rice, William G., Schmitt, Clemens, Lowe, Scott W., Johnstone, Ricky W., Pearson, Richard B., McArthur, Grant A., Hannan, Ross D.

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Dysregulation of the basal RNA polymerase transcription apparatus in cancer von Bywater, Megan J., Pearson, Richard B., McArthur, Grant A., Hannan, Ross D.

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Inhibition of Mutated, Activated BRAF in Metastatic Melanoma von Flaherty, Keith T, Puzanov, Igor, Kim, Kevin B, Ribas, Antoni, McArthur, Grant A, Sosman, Jeffrey A, O'Dwyer, Peter J, Lee, Richard J, Grippo, Joseph F, Nolop, Keith, Chapman, Paul B

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Phase III Randomized Clinical Trial Comparing Tremelimumab With Standard-of-Care Chemotherapy in Patients With Advanced Melanoma von RIBAS, Antoni, KEFFORD, Richard, LORIGAN, Paul, KENDRA, Kari L, MAIO, Michele, TREFZER, Uwe, SMYLIE, Michael, MCARTHUR, Grant A, DRENO, Brigitte, NATHAN, Paul D, MACKIEWICZ, Jacek, KIRKWOOD, John M, MARSHALL, Margaret A, GOMEZ-NAVARRO, Jesus, BO HUANG, PAVLOV, Dmitri, HAUSCHILD, Axel, PUNT, Cornelis J. A, HAANEN, John B, MARMOL, Maribel, GARBE, Claus, GOGAS, Helen, SCHACHTER, Jacob, LINETTE, Gerald

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Phase II Study of the MEK1/MEK2 Inhibitor Trametinib in Patients With Metastatic BRAF-Mutant Cutaneous Melanoma Previously Treated With or Without a BRAF Inhibitor von KIM, Kevin B, KEFFORD, Richard, GONZALEZ, Rene, OTT, Patrick A, LONG, Georgina V, GARDNER, Olivia S, OUELLET, Daniele, YANMEI XU, DEMARINI, Douglas J, LE, Ngocdiep T, PATEL, Kiran, LEWIS, Karl D, PAVLICK, Anna C, INFANTE, Jeffrey R, RIBAS, Antoni, SOSMAN, Jeffrey A, FECHER, Leslie A, MILLWARD, Michael, MCARTHUR, GrantA, HWU, Patrick

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Phase I Dose-Escalation and -Expansion Study of the BRAF Inhibitor Encorafenib (LGX818) in Metastatic BRAF -Mutant Melanoma von Delord, Jean-Pierre, Robert, Caroline, Nyakas, Marta, McArthur, Grant A, Kudchakar, Ragini, Mahipal, Amit, Yamada, Yasuhide, Sullivan, Ryan, Arance, Ana, Kefford, Richard F, Carlino, Matteo S, Hidalgo, Manuel, Gomez-Roca, Carlos, Michel, Daniela, Seroutou, Abdelkader, Aslanis, Vassilios, Caponigro, Giordano, Stuart, Darrin D, Moutouh-de Parseval, Laure, Demuth, Tim, Dummer, Reinhard

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A Microenvironment-Induced Myeloproliferative Syndrome Caused by Retinoic Acid Receptor γ Deficiency von Walkley, Carl R., Olsen, Gemma Haines, Dworkin, Sebastian, Fabb, Stewart A., Swann, Jeremy, McArthur, Grant A., Westmoreland, Susan V., Chambon, Pierre, Scadden, David T., Purton, Louise E.

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Radiotherapy Complements Immune Checkpoint Blockade von Ngiow, Shin Foong, McArthur, Grant A., Smyth, Mark J.

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UV-Associated Mutations Underlie the Etiology of MCV-Negative Merkel Cell Carcinomas von Wong, Stephen Q, Waldeck, Kelly, Vergara, Ismael A, Schröder, Jan, Madore, Jason, Wilmott, James S, Colebatch, Andrew J, De Paoli-Iseppi, Ricardo, Li, Jason, Lupat, Richard, Semple, Timothy, Arnau, Gisela Mir, Fellowes, Andrew, Leonard, J Helen, Hruby, George, Mann, Graham J, Thompson, John F, Cullinane, Carleen, Johnston, Meredith, Shackleton, Mark, Sandhu, Shahneen, Bowtell, David D L, Johnstone, Ricky W, Fox, Stephen B, McArthur, Grant A, Papenfuss, Anthony T, Scolyer, Richard A, Gill, Anthony J, Hicks, Rodney J, Tothill, Richard W

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The Advantages and Challenges of Using FDG PET/CT for Response Assessment in Melanoma in the Era of Targeted Agents and Immunotherapy von Wong, Annie N. M., McArthur, Grant A., Hofman, Michael S., Hicks, Rodney J.

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Regulation of PRMT5–MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma von AbuHammad, Shatha, Cullinane, Carleen, Martin, Claire, Bacolas, Zoe, Ward, Teresa, Chen, Huiqin, Slater, Alison, Ardley, Kerry, Kirby, Laura, Chan, Keefe T., Brajanovski, Natalie, Smith, Lorey K., Rao, Aparna D., Lelliott, Emily J., Kleinschmidt, Margarete, Vergara, Ismael A., Papenfuss, Anthony T., Lau, Peter, Ghosh, Prerana, Haupt, Sue, Haupt, Ygal, Sanij, Elaine, Poortinga, Gretchen, Pearson, Richard B., Falk, Hendrik, Curtis, David J., Stupple, Paul, Devlin, Mark, Street, Ian, Davies, Michael A., McArthur, Grant A., Sheppard, Karen E.

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RAS Mutations Are Associated With the Development of Cutaneous Squamous Cell Tumors in Patients Treated With RAF Inhibitors von OBERHOLZER, Patrick A, KEE, Damien, PIRIS, Adriano, MACCONAILL, Laura E, ROBERT, Caroline, HOFBAUER, Günther F. L, MCARTHUR, Grant A, SCHADENDORF, Dirk, GARRAWAY, Levi A, DZIUNYCZ, Piotr, SUCKER, Antje, KAMSUKOM, Nyam, JONES, Robert, RODEN, Christine, CHALK, Clinton J, ARDLIE, Kristin, PALESCANDOLO, Emanuele

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CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer von Sanij, Elaine, Hannan, Katherine M., Xuan, Jiachen, Yan, Shunfei, Ahern, Jessica E., Trigos, Anna S., Brajanovski, Natalie, Son, Jinbae, Chan, Keefe T., Kondrashova, Olga, Lieschke, Elizabeth, Wakefield, Matthew J., Frank, Daniel, Ellis, Sarah, Cullinane, Carleen, Kang, Jian, Poortinga, Gretchen, Nag, Purba, Deans, Andrew J., Khanna, Kum Kum, Mileshkin, Linda, McArthur, Grant A., Soong, John, Berns, Els M. J. J., Hannan, Ross D., Scott, Clare L., Sheppard, Karen E., Pearson, Richard B.

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Checkpoint inhibitors in melanoma and early phase development in solid tumors: what's the future? von Ascierto, Paolo A, McArthur, Grant A

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Immunomodulatory Effects of BRAF, MEK, and CDK4/6 Inhibitors: Implications for Combining Targeted Therapy and Immune Checkpoint Blockade for the Treatment of Melanoma von Lelliott, Emily J., McArthur, Grant A., Oliaro, Jane, Sheppard, Karen E.

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Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma von Bollag, Gideon, Hirth, Peter, Tsai, James, Zhang, Jiazhong, Ibrahim, Prabha N., Cho, Hanna, Spevak, Wayne, Zhang, Chao, Zhang, Ying, Habets, Gaston, Burton, Elizabeth A., Wong, Bernice, Tsang, Garson, West, Brian L., Powell, Ben, Shellooe, Rafe, Marimuthu, Adhirai, Nguyen, Hoa, Zhang, Kam Y. J., Artis, Dean R., Schlessinger, Joseph, Su, Fei, Higgins, Brian, Iyer, Raman, D’Andrea, Kurt, Koehler, Astrid, Stumm, Michael, Lin, Paul S., Lee, Richard J., Grippo, Joseph, Puzanov, Igor, Kim, Kevin B., Ribas, Antoni, McArthur, Grant A., Sosman, Jeffrey A., Chapman, Paul B., Flaherty, Keith T., Xu, Xiaowei, Nathanson, Katherine L., Nolop, Keith

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