Exploration of a potent PI3 kinase/mTOR inhibitor as a novel anti-fibrotic agent in IPF von Mercer, Paul F, Woodcock, Hannah V, Eley, Jessica D, Platé, Manuela, Sulikowski, Michal G, Durrenberger, Pascal F, Franklin, Linda, Nanthakumar, Carmel B, Man, Yim, Genovese, Federica, McAnulty, Robin J, Yang, Shuying, Maher, Toby M, Nicholson, Andrew G, Blanchard, Andy D, Marshall, Richard P, Lukey, Pauline T, Chambers, Rachel C

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Delivery of ENaC siRNA to epithelial cells mediated by a targeted nanocomplex: a therapeutic strategy for cystic fibrosis von Manunta, Maria D. I., Tagalakis, Aristides D., Attwood, Martin, Aldossary, Ahmad M., Barnes, Josephine L., Munye, Mustafa M., Weng, Alexander, McAnulty, Robin J, Hart, Stephen L.

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Fibroblasts and myofibroblasts: Their source, function and role in disease von McAnulty, Robin J.

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Prostanoid EP₂ Receptors Are Up-Regulated in Human Pulmonary Arterial Hypertension: A Key Anti-Proliferative Target for Treprostinil in Smooth Muscle Cells von Patel, Jigisha A, Shen, Lei, Hall, Susan M, Benyahia, Chabha, Norel, Xavier, McAnulty, Robin J, Moledina, Shahin, Silverstein, Adam M, Whittle, Brendan J, Clapp, Lucie H

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Genetic partitioning of interleukin‐6 signalling in mice dissociates Stat3 from Smad3‐mediated lung fibrosis von O'Donoghue, Robert J. J., Knight, Darryl A., Richards, Carl D., Prêle, Cecilia M., Lau, Hui Ling, Jarnicki, Andrew G., Jones, Jessica, Bozinovski, Steven, Vlahos, Ross, Thiem, Stefan, McKenzie, Brent S., Wang, Bo, Stumbles, Philip, Laurent, Geoffrey J., McAnulty, Robin J., Rose‐John, Stefan, Zhu, Hong Jian, Anderson, Gary P., Ernst, Matthias R., Mutsaers, Steven E.

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Tgf-Beta isoform specific regulation of airway inflammation and remodelling in a murine model of asthma von Bottoms, Stephen E, Howell, Jane E, Reinhardt, Alistair K, Evans, Iona C, McAnulty, Robin J

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Pulmonary Epithelium Is a Prominent Source of Proteinase-activated Receptor-1-inducible CCL2 in Pulmonary Fibrosis von Mercer, Paul F, Johns, Robin H, Scotton, Chris J, Krupiczojc, Malvina A, Konigshoff, Melanie, Howell, David C. J, McAnulty, Robin J, Das, Anuk, Thorley, Andrew J, Tetley, Terry D, Eickelberg, Oliver, Chambers, Rachel C

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Fibroproliferation occurs early in the acute respiratory distress syndrome and impacts on outcome von MARSHALL, Richard P, BELLINGAN, Geoffrey, WEBB, Suzanne, PUDDICOMBE, Anna, GOLDSACK, Neil, MCANULTY, Robin J, LAURENT, Geoffrey J

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Angiotensin II and the fibroproliferative response to acute lung injury von Marshall, Richard P, Gohlke, Peter, Chambers, Rachel C, Howell, David C, Bottoms, Steve E, Unger, Thomas, McAnulty, Robin J, Laurent, Geoffrey J

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Nebulisation of receptor-targeted nanocomplexes for gene delivery to the airway epithelium von Manunta, Maria D I, McAnulty, Robin J, Tagalakis, Aristides D, Bottoms, Stephen E, Campbell, Frederick, Hailes, Helen C, Tabor, Alethea B, Laurent, Geoffrey J, O'Callaghan, Christopher, Hart, Stephen L

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Caffeine inhibits TGFβ activation in epithelial cells, interrupts fibroblast responses to TGFβ, and reduces established fibrosis in ex vivo precision-cut lung slices von Tatler, Amanda L, Barnes, Josephine, Habgood, Anthony, Goodwin, Amanda, McAnulty, Robin J, Jenkins, Gisli

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Angiotensin II is mitogenic for human lung fibroblasts via activation of the type 1 receptor von MARSHALL, R. P, MCANULTY, R. J, LAURENT, G. J

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Reduced SOCS1 Expression in Lung Fibroblasts from Patients with IPF Is Not Mediated by Promoter Methylation or Mir155 von Prele, Cecilia M., Iosifidis, Thomas, McAnulty, Robin J., Pearce, David R., Badrian, Bahareh, Miles, Tylah, Jamieson, Sarra E., Ernst, Matthias, Thompson, Philip J., Laurent, Geoffrey J., Knight, Darryl A., Mutsaers, Steven E.

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Inverse Effects of Interleukin-6 on Apoptosis of Fibroblasts from Pulmonary Fibrosis and Normal Lungs von Moodley, Yuben P, Misso, Neil L. A, Scaffidi, Amelia K, Fogel-Petrovic, Mirjana, McAnulty, Robin J, Laurent, Geoffrey J, Thompson, Philip J, Knight, Darryl A

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Direct Thrombin Inhibition Reduces Lung Collagen, Accumulation, and Connective Tissue Growth Factor mRNA Levels in Bleomycin-Induced Pulmonary Fibrosis von Howell, David C.J., Goldsack, Neil R., Marshall, Richard P., McAnulty, Robin J., Starke, Richard, Purdy, Gordon, Laurent, Geoffrey J., Chambers, Rachel C.

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Mast cell tryptase stimulates human lung fibroblast proliferation via protease-activated receptor-2 von Akers, Ian A, Parsons, Maddy, Hill, Michael R, Hollenberg, Morley D, Sanjar, Shahin, Laurent, Geoffrey J, McAnulty, Robin J

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Plasma cell but not CD20-mediated B-cell depletion protects from bleomycin-induced lung fibrosis von Prêle, Cecilia M., Miles, Tylah, Pearce, David R., O'Donoghue, Robert J., Grainge, Chris, Barrett, Lucy, Birnie, Kimberly, Lucas, Andrew D., Baltic, Svetlana, Ernst, Matthias, Rinaldi, Catherine, Laurent, Geoffrey J., Knight, Darryl A., Fear, Mark, Hoyne, Gerard, McAnulty, Robin J., Mutsaers, Steven E.

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Transcriptome analysis of IPF fibroblastic foci identifies key pathways involved in fibrogenesis von Guillotin, Delphine, Taylor, Adam R, Platé, Manuela, Mercer, Paul F, Edwards, Lindsay M, Haggart, Ross, Miele, Gino, McAnulty, Robin J, Maher, Toby M, Hynds, Robert E, Jamal-Hanjani, Mariam, Marshall, Richard P, Fisher, Andrew J, Blanchard, Andy D, Chambers, Rachel C

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Effective silencing of ENaC by siRNA delivered with epithelial-targeted nanocomplexes in human cystic fibrosis cells and in mouse lung von Tagalakis, Aristides D, Munye, Mustafa M, Ivanova, Rositsa, Chen, Hanpeng, Smith, Claire M, Aldossary, Ahmad M, Rosa, Luca Z, Moulding, Dale, Barnes, Josephine L, Kafetzis, Konstantinos N, Jones, Stuart A, Baines, Deborah L, Moss, Guy W J, O’Callaghan, Christopher, McAnulty, Robin J, Hart, Stephen L

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Diminished Prostaglandin E2 Contributes to the Apoptosis Paradox in Idiopathic Pulmonary Fibrosis von MAHER, Toby M, EVANS, Lona C, BOTTOMS, Stephen E, MERCER, Paul F, THORLEY, Andrew J, NICHOLSON, Andrew G, LAURENT, Geoffrey J, TETLEY, Teresa D, CHAMBERS, Rachel C, MCANULTY, Robin J

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