Anti-selective [3+2] (Hetero)annulation of non-conjugated alkenes via directed nucleopalladation von Ni, Hui-Qi, Kevlishvili, Ilia, Bedekar, Pranali G., Barber, Joyann S., Yang, Shouliang, Tran-Dubé, Michelle, Romine, Andrew M., Lu, Hou-Xiang, McAlpine, Indrawan J., Liu, Peng, Engle, Keary M.

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Rhodium(III)-Catalyzed C–H Activation: Ligand-Controlled Regioselective Synthesis of 4‑Methyl-Substituted Dihydroisoquinolones von Barber, Joyann S, Scales, Stephanie, Tran-Dubé, Michelle, Wang, Fen, Sach, Neal W, Bernier, Louise, Collins, Michael R, Zhu, JinJiang, McAlpine, Indrawan J, Patman, Ryan L

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Anti-selective Cyclopropanation of Nonconjugated Alkenes with Diverse Pronucleophiles via Directed Nucleopalladation von Ni, Hui-Qi, Alturaifi, Turki M., Rodphon, Warabhorn, Scherschel, Nicholas F., Yang, Shouliang, Wang, Fen, McAlpine, Indrawan J., Piercey, Davin G., Liu, Peng, Engle, Keary M.

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SAM-Competitive PRMT5 Inhibitor PF-06939999 Demonstrates Antitumor Activity in Splicing Dysregulated NSCLC with Decreased Liability of Drug Resistance von Jensen-Pergakes, Kristen, Tatlock, John, Maegley, Karen A, McAlpine, Indrawan J, McTigue, Michele, Xie, Tao, Dillon, Christopher P, Wang, Yuli, Yamazaki, Shinji, Spiegel, Noah, Shi, Manli, Nemeth, Amy, Miller, Natalie, Hendrickson, Eleanore, Lam, Hieu, Sherrill, John, Chung, Chi-Yeh, McMillan, Elizabeth A, Bryant, Shannon Karlicek, Palde, Prakash, Braganza, John, Brooun, Alexei, Deng, Ya-Li, Goshtasbi, Vesta, Kephart, Susan E, Kumpf, Robert A, Liu, Wei, Patman, Ryan L, Rui, Eugene, Scales, Stephanie, Tran-Dube, Michelle, Wang, Fen, Wythes, Martin, Paul, Thomas A

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Multifaceted Substrate–Ligand Interactions Promote the Copper-Catalyzed Hydroboration of Benzylidenecyclobutanes and Related Compounds von Kang, Taeho, Erbay, Tuğçe G, Xu, Kane L, Gallego, Gary M, Burtea, Alexander, Nair, Sajiv K, Patman, Ryan L, Zhou, Ru, Sutton, Scott C, McAlpine, Indrawan J, Liu, Peng, Engle, Keary M

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Catalytic σ‐Bond Annulation with Ambiphilic Organohalides Enabled by β‐X Elimination von Ni, Hui‐Qi, Dai, Jing‐Cheng, Yang, Shouliang, Loach, Richard P., Chuba, Matthew D., McAlpine, Indrawan J., Engle, Keary M.

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Mapping Ambiphile Reactivity Trends in the Anti‐(Hetero)annulation of Non‐Conjugated Alkenes via PdII/PdIV Catalysis von Ni, Hui‐Qi, Cooper, Phillippa, Yang, Shouliang, Wang, Fen, Sach, Neal, Bedekar, Pranali G., Donaldson, Joyann S., Tran‐Dubé, Michelle, McAlpine, Indrawan J., Engle, Keary M.

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Synthetic Approaches to the New Drugs Approved During 2021 von McInturff, Emma L., France, Scott P., Leverett, Carolyn A., Flick, Andrew C., Lindsey, Erick A., Berritt, Simon, Carney, Daniel W., DeForest, Jacob C., Ding, Hong X., Fink, Sarah J., Gibson, Tony S., Gray, Kaitlyn, Hubbell, Aran K., Johnson, Amber M., Liu, Yiyang, Mahapatra, Subham, McAlpine, Indrawan J., Watson, Rebecca B., O’Donnell, Christopher J.

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Mapping Ambiphile Reactivity Trends in the Anti-(Hetero)annulation of Non-Conjugated Alkenes via Pd II /Pd IV Catalysis von Ni, Hui-Qi, Cooper, Phillippa, Yang, Shouliang, Wang, Fen, Sach, Neal, Bedekar, Pranali G, Donaldson, Joyann S, Tran-Dubé, Michelle, McAlpine, Indrawan J, Engle, Keary M

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Copper-Catalyzed Chan–Lam Cyclopropylation of Phenols and Azaheterocycles von Derosa, Joseph, O’Duill, Miriam L, Holcomb, Matthew, Boulous, Mark N, Patman, Ryan L, Wang, Fen, Tran-Dubé, Michelle, McAlpine, Indrawan, Engle, Keary M

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Synthesis of Small 3‑Fluoro- and 3,3-Difluoropyrrolidines Using Azomethine Ylide Chemistry von McAlpine, Indrawan, Tran-Dubé, Michelle, Wang, Fen, Scales, Stephanie, Matthews, Jean, Collins, Michael R, Nair, Sajiv K, Nguyen, Mary, Bian, Jianwei, Alsina, Luis Martinez, Sun, Jianmin, Zhong, Jiaying, Warmus, Joseph S, O’Neill, Brian T

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Discovery of Potent, Selective, and Peripherally Restricted Pan-Trk Kinase Inhibitors for the Treatment of Pain von Bagal, Sharan K, Andrews, Mark, Bechle, Bruce M, Bian, Jianwei, Bilsland, James, Blakemore, David C, Braganza, John F, Bungay, Peter J, Corbett, Matthew S, Cronin, Ciaran N, Cui, Jingrong Jean, Dias, Rebecca, Flanagan, Neil J, Greasley, Samantha E, Grimley, Rachel, James, Kim, Johnson, Eric, Kitching, Linda, Kraus, Michelle L, McAlpine, Indrawan, Nagata, Asako, Ninkovic, Sacha, Omoto, Kiyoyuki, Scales, Stephanie, Skerratt, Sarah E, Sun, Jianmin, Tran-Dubé, Michelle, Waldron, Gareth J, Wang, Fen, Warmus, Joseph S

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Catalytic σ‐Bond Annulation with Ambiphilic Organohalides Enabled by β‐X Elimination von Ni, Hui‐Qi, Dai, Jing‐Cheng, Yang, Shouliang, Loach, Richard P., Chuba, Matthew D., McAlpine, Indrawan J., Engle, Keary M.

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Mechanistic investigation of imatinib-induced cardiac toxicity and the involvement of c-Abl kinase von Hu, Wenyue, Lu, Shuyan, McAlpine, Indrawan, Jamieson, Joseph D, Lee, Dong U, Marroquin, Lisa D, Heyen, Jonathan R, Jessen, Bart A

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Discovery of Pyrroloaminopyrazoles as Novel PAK Inhibitors von Guo, Chuangxing, McAlpine, Indrawan, Zhang, Junhu, Knighton, Daniel D, Kephart, Susan, Johnson, M. Catherine, Li, Haitao, Bouzida, Djamal, Yang, Anle, Dong, Liming, Marakovits, Joseph, Tikhe, Jayashree, Richardson, Paul, Guo, Lisa C, Kania, Robert, Edwards, Martin P, Kraynov, Eugenia, Christensen, James, Piraino, Joseph, Lee, Joseph, Dagostino, Eleanor, Del-Carmen, Christine, Deng, Ya-Li, Smeal, Tod, Murray, Brion W

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Mapping Ambiphile Reactivity Trends in the Anti‐(Hetero)annulation of Non‐Conjugated Alkenes via PdII/PdIV Catalysis von Ni, Hui‐Qi, Cooper, Phillippa, Yang, Shouliang, Wang, Fen, Sach, Neal, Bedekar, Pranali G., Donaldson, Joyann S., Tran‐Dubé, Michelle, McAlpine, Indrawan J., Engle, Keary M.

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Practical synthesis of 1-alkyl 5-methyl ester 1,2,3-triazoles from low boiling point azides von Wang, Fen, Yang, Shouliang, Castanedo, Alberto, Braganza, John, McAlpine, Indrawan

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737 Inhibition of P21-activated kinase 4 (PAK4) reverts immune exclusion and restores anti-tumor immunity in the tumor microenvironment von Zhou, Yu 'Jerry', Chu, Gina, Hendrickson, Eleanore, Gullo-Brown, Johnni, Chavez, Brandy, McAlpine, Indrawan, Rui, Eugene, Doran, Shawn, Timofeevski, Sergei, Heyen, Jonathan, Kinong, Jennifer, Tang, Szu-Yu, Oyer, Jon, Rayannavar, Vinayak, Nager, Andrew, Ching, Keith, Shi, Stephanie, Bhadra, Rajarshi, Dillon, Christopher, Gururajan, Murali

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Mapping Ambiphile Reactivity Trends in the Anti-(Hetero)annulation of Non-Conjugated Alkenes via Pd(II)/Pd(IV) Catalysis von Ni, Hui-Qi, Cooper, Phillippa, Yang, Shouliang, Wang, Fen, Sach, Neal, Bedekar, Pranali G., Donaldson, Joyann S., Tran-Dubé, Michelle, McAlpine, Indrawan J., Engle, Keary M.

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A Disconnection for Rapid Access to Heterocyclic Benzylic Amines with Fully Substituted α‑Carbons von Yang, Shouliang, Wang, Fen, Scales, Stephanie, Tran-Dubé, Michelle, Berry, Madeline, Xu, Haiwei, Tang, Feng, Xue, Liangliang, Ma, Zhongwei, Li, Bryan, McAlpine, Indrawan

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