Urokinase Plasminogen Activator Receptor Choreographs Multiple Ligand Interactions: Implications for Tumor Progression and Therapy von MAZAR, Andrew P

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Mesothelial cells promote early ovarian cancer metastasis through fibronectin secretion von Kenny, Hilary A, Chiang, Chun-Yi, White, Erin A, Schryver, Elizabeth M, Habis, Mohammed, Romero, Iris L, Ladanyi, Andras, Penicka, Carla V, George, Joshy, Matlin, Karl, Montag, Anthony, Wroblewski, Kristen, Yamada, S Diane, Mazar, Andrew P, Bowtell, David, Lengyel, Ernst

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Targeting SOD1 reduces experimental non–small-cell lung cancer von Glasauer, Andrea, Sena, Laura A, Diebold, Lauren P, Mazar, Andrew P, Chandel, Navdeep S

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Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation von Calvert, Andrea E., Chalastanis, Alexandra, Wu, Yongfei, Hurley, Lisa A., Kouri, Fotini M., Bi, Yingtao, Kachman, Maureen, May, Jasmine L., Bartom, Elizabeth, Hua, Youjia, Mishra, Rama K., Schiltz, Gary E., Dubrovskyi, Oleksii, Mazar, Andrew P., Peter, Marcus E., Zheng, Hongwu, James, C. David, Burant, Charles F., Chandel, Navdeep S., Davuluri, Ramana V., Horbinski, Craig, Stegh, Alexander H.

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Glycogen Synthase Kinase-3 Inhibition Sensitizes Pancreatic Cancer Cells to Chemotherapy by Abrogating the TopBP1/ATR-Mediated DNA Damage Response von Ding, Li, Madamsetty, Vijay S, Kiers, Spencer, Alekhina, Olga, Ugolkov, Andrey, Dube, John, Zhang, Yu, Zhang, Jin-San, Wang, Enfeng, Dutta, Shamit K, Schmitt, Daniel M, Giles, Francis J, Kozikowski, Alan P, Mazar, Andrew P, Mukhopadhyay, Debabrata, Billadeau, Daniel D

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Molecular Pathways: Revisiting Glycogen Synthase Kinase-3β as a Target for the Treatment of Cancer von Walz, Amy, Ugolkov, Andrey, Chandra, Sunandana, Kozikowski, Alan, Carneiro, Benedito A, O'Halloran, Thomas V, Giles, Francis J, Billadeau, Daniel D, Mazar, Andrew P

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9-ING-41, a small molecule inhibitor of GSK-3beta, potentiates the effects of anticancer therapeutics in bladder cancer von Kuroki, Hiroo, Anraku, Tsutomu, Kazama, Akira, Bilim, Vladimir, Tasaki, Masayuki, Schmitt, Daniel, Mazar, Andrew P., Giles, Francis J, Ugolkov, Andrey, Tomita, Yoshihiko

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Arsenoplatin‑1 Is a Dual Pharmacophore Anticancer Agent von Miodragović, Đenana, Merlino, Antonello, Swindell, Elden P, Bogachkov, Abraham, Ahn, Richard W, Abuhadba, Sara, Ferraro, Giarita, Marzo, Tiziano, Mazar, Andrew P, Messori, Luigi, O’Halloran, Thomas V

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Biodistribution and in vivo toxicity of aptamer-loaded gold nanostars von Dam, Duncan Hieu M, Culver, Kayla S.B, Kandela, Irawati, PhD, Lee, Raymond C, Chandra, Kavita, Lee, Hyojin, PhD, Mantis, Christine, Ugolkov, Andrey, PhD, Mazar, Andrew P., PhD, Odom, Teri W., PhD

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α5β1 Integrin Signaling Mediates Oxidized Low-Density Lipoprotein–Induced Inflammation and Early Atherosclerosis von Yurdagul, Arif, Green, Jonette, Albert, Patrick, McInnis, Marshall C, Mazar, Andrew P, Orr, A Wayne

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Nano-encapsulation of arsenic trioxide enhances efficacy against murine lymphoma model while minimizing its impact on ovarian reserve in vitro and in vivo von Ahn, Richard W, Barrett, Susan L, Raja, Meera R, Jozefik, Jennifer K, Spaho, Lidia, Chen, Haimei, Bally, Marcel B, Mazar, Andrew P, Avram, Michael J, Winter, Jane N, Gordon, Leo I, Shea, Lonnie D, O'Halloran, Thomas V, Woodruff, Teresa K

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Human Organoids Share Structural and Genetic Features with Primary Pancreatic Adenocarcinoma Tumors von Romero-Calvo, Isabel, Weber, Christopher R, Ray, Mohana, Brown, Miguel, Kirby, Kori, Nandi, Rajib K, Long, Tiha M, Sparrow, Samantha M, Ugolkov, Andrey, Qiang, Wenan, Zhang, Yilin, Brunetti, Tonya, Kindler, Hedy, Segal, Jeremy P, Rzhetsky, Andrey, Mazar, Andrew P, Buschmann, Mary M, Weichselbaum, Ralph, Roggin, Kevin, White, Kevin P

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Mesenchymal stromal cells enhance self-assembly of a HUVEC tubular network through uPA-uPAR/VEGFR2/integrin/NOTCH crosstalk von Beloglazova, Irina, Stepanova, Victoria, Zubkova, Ekaterina, Dergilev, Konstantin, Koptelova, Natalia, Tyurin-Kuzmin, Pyotr A., Dyikanov, Daniyar, Plekhanova, Olga, Cines, Douglas B., Mazar, Andrew P., Parfyonova, Yelena

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Melanoma Cells Block PEDF Production in Fibroblasts to Induce the Tumor-Promoting Phenotype of Cancer-Associated Fibroblasts von Nwani, Nkechiyere G, Deguiz, Maria L, Jimenez, Benilde, Vinokour, Elena, Dubrovskyi, Oleksii, Ugolkov, Andrey, Mazar, Andrew P, Volpert, Olga V

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Inhibition of DNA damage repair by the CDK4/6 inhibitor palbociclib delays irradiated intracranial atypical teratoid rhabdoid tumor and glioblastoma xenograft regrowth von Hashizume, Rintaro, Zhang, Ali, Mueller, Sabine, Prados, Michael D, Lulla, Rishi R, Goldman, Stewart, Saratsis, Amanda M, Mazar, Andrew P, Stegh, Alexander H, Cheng, Shi-Yuan, Horbinski, Craig, Haas-Kogan, Daphne A, Sarkaria, Jann N, Waldman, Todd, James, C David

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GSK-3 inhibition overcomes chemoresistance in human breast cancer von Ugolkov, Andrey, Gaisina, Irina, Zhang, Jin-San, Billadeau, Daniel D, White, Kevin, Kozikowski, Alan, Jain, Sarika, Cristofanilli, Massimo, Giles, Francis, O'Halloran, Thomas, Cryns, Vincent L, Mazar, Andrew P

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Identification of a new epitope in uPAR as a target for the cancer therapeutic monoclonal antibody ATN-658, a structural homolog of the uPAR binding integrin CD11b (αM) von Xu, Xiang, Cai, Yuan, Wei, Ying, Donate, Fernando, Juarez, Jose, Parry, Graham, Chen, Liqing, Meehan, Edward J, Ahn, Richard W, Ugolkov, Andrey, Dubrovskyi, Oleksii, O'Halloran, Thomas V, Huang, Mingdong, Mazar, Andrew P

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Differential Response of Glioma Stem Cells to Arsenic Trioxide Therapy Is Regulated by MNK1 and mRNA Translation von Bell, Jonathan B, Eckerdt, Frank, Dhruv, Harshil D, Finlay, Darren, Peng, Sen, Kim, Seungchan, Kroczynska, Barbara, Beauchamp, Elspeth M, Alley, Kristen, Clymer, Jessica, Goldman, Stewart, Cheng, Shi-Yuan, James, C David, Nakano, Ichiro, Horbinski, Craig, Mazar, Andrew P, Vuori, Kristiina, Kumthekar, Priya, Raizer, Jeffrey, Berens, Michael E, Platanias, Leonidas C

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The Landscape of Glycogen Synthase Kinase-3 Beta Genomic Alterations in Cancer von Borden, Brittany A, Baca, Yasmine, Xiu, Joanne, Tavora, Fabio, Winer, Ira, Weinberg, Benjamin A, Vanderwalde, Ari M, Darabi, Sourat, Korn, W Michael, Mazar, Andrew P, Giles, Francis J, Crawford, Lorin, Safran, Howard, El-Deiry, Wafik S, Carneiro, Benedito A

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uPAR antibody (huATN-658) and Zometa reduce breast cancer growth and skeletal lesions von Mahmood, Niaz, Arakelian, Ani, Khan, Haseeb Ahmed, Tanvir, Imrana, Mazar, Andrew P, Rabbani, Shafaat A

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