Advances in recombinant protein expression for use in pharmaceutical research von Assenberg, Rene, Wan, Paul T, Geisse, Sabine, Mayr, Lorenz M

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In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model von Carreras, Alba, Pane, Luna Simona, Nitsch, Roberto, Madeyski-Bengtson, Katja, Porritt, Michelle, Akcakaya, Pinar, Taheri-Ghahfarokhi, Amir, Ericson, Elke, Bjursell, Mikael, Perez-Alcazar, Marta, Seeliger, Frank, Althage, Magnus, Knöll, Ralph, Hicks, Ryan, Mayr, Lorenz M, Perkins, Rosie, Lindén, Daniel, Borén, Jan, Bohlooly-Y, Mohammad, Maresca, Marcello

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Development of an ObLiGaRe Doxycycline Inducible Cas9 system for pre-clinical cancer drug discovery von Lundin, Anders, Porritt, Michelle J., Jaiswal, Himjyot, Seeliger, Frank, Johansson, Camilla, Bidar, Abdel Wahad, Badertscher, Lukas, Wimberger, Sandra, Davies, Emma J., Hardaker, Elizabeth, Martins, Carla P., James, Emily, Admyre, Therese, Taheri-Ghahfarokhi, Amir, Bradley, Jenna, Schantz, Anna, Alaeimahabadi, Babak, Clausen, Maryam, Xu, Xiufeng, Mayr, Lorenz M., Nitsch, Roberto, Bohlooly-Y, Mohammad, Barry, Simon T., Maresca, Marcello

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Engineered Cas9 extracellular vesicles as a novel gene editing tool von Osteikoetxea, Xabier, Silva, Andreia, Lázaro‐Ibáñez, Elisa, Salmond, Nikki, Shatnyeva, Olga, Stein, Josia, Schick, Jan, Wren, Stephen, Lindgren, Julia, Firth, Mike, Madsen, Alexandra, Mayr, Lorenz M., Overman, Ross, Davies, Rick, Dekker, Niek

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Novel trends in high-throughput screening von Mayr, Lorenz M, Bojanic, Dejan

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Blocking phospholamban with VHH intrabodies enhances contractility and relaxation in heart failure von De Genst, Erwin, Foo, Kylie S., Xiao, Yao, Rohner, Eduarde, de Vries, Emma, Sohlmér, Jesper, Witman, Nevin, Hidalgo, Alejandro, Kolstad, Terje R. S., Louch, William E., Pehrsson, Susanne, Park, Andrew, Ikeda, Yasuhiro, Li, Xidan, Mayr, Lorenz M., Wickson, Kate, Jennbacken, Karin, Hansson, Kenny, Fritsche-Danielson, Regina, Hunt, James, Chien, Kenneth R.

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Secretome screening reveals immunomodulating functions of IFNα-7, PAP and GDF-7 on regulatory T-cells von Ding, Mei, Malhotra, Rajneesh, Ottosson, Tomas, Lundqvist, Magnus, Mebrahtu, Aman, Brengdahl, Johan, Gehrmann, Ulf, Bäck, Elisabeth, Ross-Thriepland, Douglas, Isaksson, Ida, Magnusson, Björn, Sachsenmeier, Kris F., Tegel, Hanna, Hober, Sophia, Uhlén, Mathias, Mayr, Lorenz M., Davies, Rick, Rockberg, Johan, Schiavone, Lovisa Holmberg

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In vivo CRISPR editing with no detectable genome-wide off-target mutations von Akcakaya, Pinar, Bobbin, Maggie L., Guo, Jimmy A., Malagon-Lopez, Jose, Clement, Kendell, Garcia, Sara P., Fellows, Mick D., Porritt, Michelle J., Firth, Mike A., Carreras, Alba, Baccega, Tania, Seeliger, Frank, Bjursell, Mikael, Tsai, Shengdar Q., Nguyen, Nhu T., Nitsch, Roberto, Mayr, Lorenz M., Pinello, Luca, Bohlooly-Y, Mohammad, Aryee, Martin J., Maresca, Marcello, Joung, J. Keith

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The Future of High-Throughput Screening von Mayr, Lorenz M., Fuerst, Peter

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Attempts to Express the A1-GMCSF Immunotoxin in the Baculovirus Expression Vector System von JAHANIAN-NAJAFABADI, Ali, BOUZARI, Saeid, OLOOMI, Mana, HABIBI ROUDKENAR, Mehryar, MAYR, Lorenz M.

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Decoding non-random mutational signatures at Cas9 targeted sites von Taheri-Ghahfarokhi, Amir, Taylor, Benjamin J M, Nitsch, Roberto, Lundin, Anders, Cavallo, Anna-Lina, Madeyski-Bengtson, Katja, Karlsson, Fredrik, Clausen, Maryam, Hicks, Ryan, Mayr, Lorenz M, Bohlooly-Y, Mohammad, Maresca, Marcello

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Single fluorescent protein-based Ca2+ sensors with increased dynamic range von Souslova, Ekaterina A, Belousov, Vsevolod V, Lock, John G, Strömblad, Staffan, Kasparov, Sergey, Bolshakov, Alexey P, Pinelis, Vsevolod G, Labas, Yulii A, Lukyanov, Sergey, Mayr, Lorenz M, Chudakov, Dmitriy M

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Suppressor of Cytokine Signaling-3 Is Recruited to the Activated Granulocyte-Colony Stimulating Factor Receptor and Modulates its Signal Transduction von Hortner, Michael, Nielsch, Ulrich, Mayr, Lorenz M, Johnston, James A, Heinrich, Peter C, Haan, Serge

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Development of a novel Gateway-based vector system for efficient, multiparallel protein expression in Escherichia coli von Freuler, Felix, Stettler, Thomas, Meyerhofer, Marco, Leder, Lukas, Mayr, Lorenz M.

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Protein production for structural biology: new solutions to new challenges von Berger, Imre, Mayr, Lorenz M

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The structure of Ca2+ sensor Case16 reveals the mechanism of reaction to low Ca2+ concentrations von Leder, Lukas, Stark, Wilhelm, Freuler, Felix, Marsh, May, Meyerhofer, Marco, Stettler, Thomas, Mayr, Lorenz M, Britanova, Olga V, Strukova, Lydia A, Chudakov, Dmitriy M, Souslova, Ekaterina A

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High throughput generation of a resource of the human secretome in mammalian cells von Tegel, Hanna, Dannemeyer, Melanie, Kanje, Sara, Sivertsson, Åsa, Berling, Anna, Svensson, Anne-Sophie, Hober, Andreas, Enstedt, Henric, Volk, Anna-Luisa, Lundqvist, Magnus, Moradi, Mona, Afshari, Delaram, Ekblad, Siri, Xu, LanLan, Westin, Malin, Bidad, Faranak, Schiavone, Lovisa Holmberg, Davies, Rick, Mayr, Lorenz M., Knight, Sinead, Göpel, Sven O., Voldborg, Björn G., Edfors, Fredrik, Forsström, Björn, von Feilitzen, Kalle, Zwahlen, Martin, Rockberg, Johan, Takanen, Jenny Ottosson, Uhlén, Mathias, Hober, Sophia

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Endosomal escape enhancing compounds facilitate functional delivery of extracellular vesicle cargo von Heath, Nikki, Osteikoetxea, Xabier, de Oliveria, Taiana Mia, Lázaro-Ibáñez, Elisa, Shatnyeva, Olga, Schindler, Christina, Tigue, Natalie, Mayr, Lorenz M, Dekker, Niek, Overman, Ross, Davies, Rick

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Time reduction and process optimization of the baculovirus expression system for more efficient recombinant protein production in insect cells von Philipps, Björn, Rotmann, Daniel, Wicki, Micha, Mayr, Lorenz M, Forstner, Michael

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Stabilization of a protein by guanidinium chloride von Mayr, Lorenz M, Schmid, Franz X

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