The promise and challenges of immune agonist antibody development in cancer von Mayes, Patrick A., Hance, Kenneth W., Hoos, Axel

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Novel anti–B-cell maturation antigen antibody-drug conjugate (GSK2857916) selectively induces killing of multiple myeloma von Tai, Yu-Tzu, Mayes, Patrick A., Acharya, Chirag, Zhong, Mike Y., Cea, Michele, Cagnetta, Antonia, Craigen, Jenny, Yates, John, Gliddon, Louise, Fieles, William, Hoang, Bao, Tunstead, James, Christie, Amanda L., Kung, Andrew L., Richardson, Paul, Munshi, Nikhil C., Anderson, Kenneth C.

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ATF4 Regulates MYC-Mediated Neuroblastoma Cell Death upon Glutamine Deprivation von Qing, Guoliang, Li, Bo, Vu, Annette, Skuli, Nicolas, Walton, Zandra E., Liu, Xueyuan, Mayes, Patrick A., Wise, David R., Thompson, Craig B., Maris, John M., Hogarty, Michael D., Simon, M. Celeste

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RNAi screen of the protein kinome identifies checkpoint kinase 1 (CHK1) as a therapeutic target in neuroblastoma von Cole, Kristina A, Huggins, Jonathan, Laquaglia, Michael, Hulderman, Chase E, Russell, Mike R, Bosse, Kristopher, Diskin, Sharon J, Attiyeh, Edward F, Sennett, Rachel, Norris, Geoffrey, Laudenslager, Marci, Wood, Andrew C, Mayes, Patrick A, Jagannathan, Jayanti, Winter, Cynthia, Mosse, Yael P, Maris, John M

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What are caspases 3 and 7 doing upstream of the mitochondria? von Kuribayashi, Kageaki, Mayes, Patrick A., El-Deiry, Wafik S.

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The BRAF and MEK Inhibitors Dabrafenib and Trametinib: Effects on Immune Function and in Combination with Immunomodulatory Antibodies Targeting PD-1, PD-L1, and CTLA-4 von Liu, Li, Mayes, Patrick A, Eastman, Stephen, Shi, Hong, Yadavilli, Sapna, Zhang, Tianqian, Yang, Jingsong, Seestaller-Wehr, Laura, Zhang, Shu-Yun, Hopson, Chris, Tsvetkov, Lyuben, Jing, Junping, Zhang, Shu, Smothers, James, Hoos, Axel

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CXCR5 and ICOS expression identifies a CD8 T-cell subset with TFH features in Hodgkin lymphomas von Le, Kieu-Suong, Amé-Thomas, Patricia, Tarte, Karin, Gondois-Rey, Françoise, Granjeaud, Samuel, Orlanducci, Florence, Foucher, Etienne D., Broussais, Florence, Bouabdallah, Reda, Fest, Thierry, Leroux, Dominique, Yadavilli, Sapna, Mayes, Patrick A., Xerri, Luc, Olive, Daniel

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TNFSF10 (TRAIL), a p53 target gene that mediates p53-dependent cell death von Kuribayashi, Kageaki, Krigsfeld, Gabriel, Wang, Wenge, Xu, JIng, Mayes, Patrick A., Dicker, David T., Wu, Gen Sheng, El-Deiry, Wafik S.

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Mitogen‐activated protein kinase (MEK/ERK) inhibition sensitizes cancer cells to centromere‐associated protein E inhibition von Mayes, Patrick A., Degenhardt, Yan Y., Wood, Andrew, Toporovskya, Yana, Diskin, Sharon J., Haglund, Elizabeth, Moy, Christopher, Wooster, Richard, Maris, John M.

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Evaluation of B cell maturation antigen as a target for antibody drug conjugate mediated cytotoxicity in multiple myeloma von Lee, Lydia, Bounds, Danton, Paterson, Jennifer, Herledan, Gaelle, Sully, Katherine, Seestaller‐Wehr, Laura M., Fieles, William E., Tunstead, James, McCahon, Lee, Germaschewski, Fiona M., Mayes, Patrick A, Craigen, Jenny L., Rodriguez‐Justo, Manuel, Yong, Kwee L.

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Combinatorial Regulation of Neuroblastoma Tumor Progression by N-Myc and Hypoxia Inducible Factor HIF-1α von Qing, Guoliang, Skuli, Nicolas, Mayes, Patrick A., Pawel, Bruce, Martinez, Daniel, Maris, John M., Simon, M. Celeste

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Correction: Identification of TRAIL-inducing compounds highlights small molecule ONC201/TIC10 as a unique anti-cancer agent that activates the TRAIL pathway von Allen, Joshua E, Krigsfeld, Gabriel, Patel, Luv, Mayes, Patrick A, Dicker, David T, Wu, Gen Sheng, El-Deiry, Wafik S

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Identification of TRAIL-inducing compounds highlights small molecule ONC201/TIC10 as a unique anti-cancer agent that activates the TRAIL pathway von Allen, Joshua E, Krigsfeld, Gabriel, Patel, Luv, Mayes, Patrick A, Dicker, David T, Wu, Gen Sheng, El-Deiry, Wafik S

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Noninvasive vascular imaging in fluorescent tumors using multispectral unmixing von Mayes, Patrick A, Dicker, David T, Liu, Yingqiu Y, El-Deiry, Wafik S

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Integrative genomics identifies LMO1 as a neuroblastoma oncogene von Wang, Kai, Diskin, Sharon J., Zhang, Haitao, Attiyeh, Edward F., Winter, Cynthia, Hou, Cuiping, Schnepp, Robert W., Diamond, Maura, Bosse, Kristopher, Mayes, Patrick A., Glessner, Joseph, Kim, Cecilia, Frackelton, Edward, Garris, Maria, Wang, Qun, Glaberson, Wendy, Chiavacci, Rosetta, Le Nguyen, Jagannathan, Jayanti, Saeki, Norihisa, Sasaki, Hiroki, Grant, Struan F. A., Iolascon, Achille, Mosse, Yael P., Cole, Kristina A., Li, Hongzhe, Devoto, Marcella, McGrady, Patrick W., London, Wendy B., Capasso, Mario, Rahman, Nazneen, Hakonarson, Hakon, Maris, John M.

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CXCR5 and ICOS expression identifies a CD8 T-cell subset with T features in Hodgkin lymphomas von Le, Kieu-Suong, Amé-Thomas, Patricia, Tarte, Karin, Gondois-Rey, Françoise, Granjeaud, Samuel, Orlanducci, Florence, Foucher, Etienne D, Broussais, Florence, Bouabdallah, Reda, Fest, Thierry, Leroux, Dominique, Yadavilli, Sapna, Mayes, Patrick A, Xerri, Luc, Olive, Daniel

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Activating Inducible T-cell Costimulator Yields Antitumor Activity Alone and in Combination with Anti-PD-1 Checkpoint Blockade von Yadavilli, Sapna, Waight, Jeremy D., Brett, Sara, Bi, Meixia, Zhang, Tianqian, Liu, Yao-Bin, Ellis, Catherine, Turner, David C., Hahn, Ashleigh, Shi, Hong, Seestaller-Wehr, Laura, Jing, Junping, Xie, Qing, Shaik, Jafar Sadik, Ji, Xiao, Gagnon, Robert, Fieles, William, Hook, Laura, Grant, Steven, Hopley, Stephanie, DeYoung, M. Phillip, Blackwell, Christina, Chisamore, Michael, Biddlecombe, Robert, Figueroa, David J., Hopson, Christopher B., Srinivasan, Roopa, Smothers, James, Maio, Michele, Rischin, Danny, Olive, Daniel, Paul, Elaine, Mayes, Patrick A., Hoos, Axel, Ballas, Marc

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Modulation of TRAIL-induced tumor cell apoptosis in a hypoxic environment von Mayes, Patrick A, Campbell, Latoya, Ricci, M Stacey, Plastaras, John P, Dicker, David T, El-Deiry, Wafik S

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Overcoming Hypoxia-Induced Apoptotic Resistance through Combinatorial Inhibition of GSK-3β and CDK1 von MAYES, Patrick A, DOLLOFF, Nathan G, DICKER, David T, BROWN, J. Martin, FURTH, Emma E, KLEIN, Peter S, SEARS, Rosalie C, EL-DEIRY, Wafik S, DANIEL, Colin J, LIU, J. Judy, HART, Lori S, KURIBAYASHI, Kageaki, ALLEN, Joshua E, JEE, David I. H, DORSEY, Jay F, LIU, Yingqiu Y

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FLT-PET may not be a reliable indicator of therapeutic response in p53-null malignancy von KATZ, Sharyn I, LANLAN ZHOU, FERRARA, Thomas A, WENGE WANG, MAYES, Patrick A, SMITH, Charles D, EL-DEIRY, Wafik S

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