Human pluripotent reprogramming with CRISPR activators von Weltner, Jere, Balboa, Diego, Katayama, Shintaro, Bespalov, Maxim, Krjutškov, Kaarel, Jouhilahti, Eeva-Mari, Trokovic, Ras, Kere, Juha, Otonkoski, Timo

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GDNF family receptor complexes are emerging drug targets von Bespalov, Maxim M, Saarma, Mart

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Heparan sulfate proteoglycan syndecan-3 is a novel receptor for GDNF, neurturin, and artemin von Bespalov, Maxim M, Sidorova, Yulia A, Tumova, Sarka, Ahonen-Bishopp, Anni, Magalhães, Ana Cathia, Kulesskiy, Evgeny, Paveliev, Mikhail, Rivera, Claudio, Rauvala, Heikki, Saarma, Mart

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Obatoclax, saliphenylhalamide and gemcitabine inhibit Zika virus infection in vitro and differentially affect cellular signaling, transcription and metabolism von Kuivanen, Suvi, Bespalov, Maxim M., Nandania, Jatin, Ianevski, Aleksandr, Velagapudi, Vidya, De Brabander, Jef K., Kainov, Denis E., Vapalahti, Olli

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Discovery of berberine, abamectin and ivermectin as antivirals against chikungunya and other alphaviruses von Varghese, Finny S., Kaukinen, Pasi, Gläsker, Sabine, Bespalov, Maxim, Hanski, Leena, Wennerberg, Krister, Kümmerer, Beate M., Ahola, Tero

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Glial cell line–derived neurotrophic factor receptor Rearranged during transfection agonist supports dopamine neurons in Vitro and enhances dopamine release In Vivo von Mahato, Arun Kumar, Kopra, Jaakko, Renko, Juho‐Matti, Visnapuu, Tanel, Korhonen, Ilari, Pulkkinen, Nita, Bespalov, Maxim M., Domanskyi, Andrii, Ronken, Eric, Piepponen, T. Petteri, Voutilainen, Merja H., Tuominen, Raimo K., Karelson, Mati, Sidorova, Yulia A., Saarma, Mart

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Individualized systems medicine strategy to tailor treatments for patients with chemorefractory acute myeloid leukemia von Pemovska, Tea, Kontro, Mika, Yadav, Bhagwan, Edgren, Henrik, Eldfors, Samuli, Szwajda, Agnieszka, Almusa, Henrikki, Bespalov, Maxim M, Ellonen, Pekka, Elonen, Erkki, Gjertsen, Bjørn T, Karjalainen, Riikka, Kulesskiy, Evgeny, Lagström, Sonja, Lehto, Anna, Lepistö, Maija, Lundán, Tuija, Majumder, Muntasir Mamun, Marti, Jesus M Lopez, Mattila, Pirkko, Murumägi, Astrid, Mustjoki, Satu, Palva, Aino, Parsons, Alun, Pirttinen, Tero, Rämet, Maria E, Suvela, Minna, Turunen, Laura, Västrik, Imre, Wolf, Maija, Knowles, Jonathan, Aittokallio, Tero, Heckman, Caroline A, Porkka, Kimmo, Kallioniemi, Olli, Wennerberg, Krister

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Developing therapeutically more efficient Neurturin variants for treatment of Parkinson's disease von Runeberg-Roos, Pia, Piccinini, Elisa, Penttinen, Anna-Maija, Mätlik, Kert, Heikkinen, Hanna, Kuure, Satu, Bespalov, Maxim M, Peränen, Johan, Garea-Rodríguez, Enrique, Fuchs, Eberhard, Airavaara, Mikko, Kalkkinen, Nisse, Penn, Richard, Saarma, Mart

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Comparison of liquid chromatography-mass spectrometry and direct infusion microchip electrospray ionization mass spectrometry in global metabolomics of cell samples von Pöhö, Päivi, Lipponen, Katriina, Bespalov, Maxim M., Sikanen, Tiina, Kotiaho, Tapio, Kostiainen, Risto

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A Novel Small Molecule GDNF Receptor RET Agonist, BT13, Promotes Neurite Growth from Sensory Neurons in Vitro and Attenuates Experimental Neuropathy in the Rat von Sidorova, Yulia A, Bespalov, Maxim M, Wong, Agnes W, Kambur, Oleg, Jokinen, Viljami, Lilius, Tuomas O, Suleymanova, Ilida, Karelson, Gunnar, Rauhala, Pekka V, Karelson, Mati, Osborne, Peregrine B, Keast, Janet R, Kalso, Eija A, Saarma, Mart

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Bone morphogenetic protein-inducer tilorone identified by high-throughput screening is antifibrotic in vivo von Leppäranta, Outi, Tikkanen, Jussi M, Bespalov, Maxim M, Koli, Katri, Myllärniemi, Marjukka

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Structure of the Glial Cell Line-derived Neurotrophic Factor-Coreceptor Complex: INSIGHTS INTO RET SIGNALING AND HEPARIN BINDING von Parkash, Vimal, Leppänen, Veli-Matti, Virtanen, Heidi, Jurvansuu, Jaana M, Bespalov, Maxim M, Sidorova, Yulia A, Runeberg-Roos, Pia, Saarma, Mart, Goldman, Adrian

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Heparin-binding determinants of GDNF reduce its tissue distribution but are beneficial for the protection of nigral dopaminergic neurons von Piltonen, Marjo, Bespalov, Maxim M., Ervasti, Dagmar, Matilainen, Tero, Sidorova, Yulia A., Rauvala, Heikki, Saarma, Mart, Männistö, Pekka T.

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The structure of GFRα1 domain 3 reveals new insights into GDNF binding and RET activation von Leppänen, Veli-Matti, Bespalov, Maxim M, Runeberg-Roos, Pia, Puurand, Ülo, Merits, Andres, Saarma, Mart, Goldman, Adrian

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Lack ofl-Iduronic Acid in Heparan Sulfate Affects Interaction with Growth Factors and Cell Signaling von Jia, Juan, Maccarana, Marco, Zhang, Xiao, Bespalov, Maxim, Lindahl, Ulf, Li, Jin-Ping

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Sensory neurons from N-syndecan-deficient mice are defective in survival von Paveliev, Mikhail, Hienola, Anni, Jokitalo, Eija, Planken, Anu, Bespalov, Maxim M, Rauvala, Heikki, Saarma, Mart

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Novel computational models for predicting dopamine interactions von Katritzky, Alan R., Dobchev, Dimitar A., Stoyanova-Slavova, Iva B., Kuanar, Minati, Bespalov, Maxim M., Karelson, Mati, Saarma, Mart

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The Elusive Turkestan Lynx at the Northwestern Edge of Geographic Range: Current Suitable Habitats and Distribution Forecast in the Climate Change von Bizhanova, Nazerke, Steiner, Moriz, Rametov, Nurkuisa, Grachev, Alexey, Grachev, Yuri, Bespalov, Maxim, Zhaparkulov, Tungyshbek, Saparbayev, Saltore, Sailaukhanuly, Amanbol, Bespalov, Sergey, Bolatuly, Aibol, Saparov, Kuandyk, Sah, Shahrul Anuar Mohd

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The first cysteine-rich domain of the receptor GFRα1 stabilizes the binding of GDNF von VIRTANEN, Heidi, YANG, Jianmin, BESPALOV, Maxim M., HILTUNEN, Jukka O., LEPPÄNEN, Veli-Matti, KALKKINEN, Nisse, GOLDMAN, Adrian, SAARMA, Mart, RUNEBERG-ROOS, Pia

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Lack of L-iduronic acid in heparan sulfate affects interaction with growth factors and cell signaling von Jia, Juan, Maccarana, Marco, Zhang, Xiao, Bespalov, Maxim, Lindahl, Ulf, Li, Jin-Ping

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