Synthesis and in Vitro and in Vivo Activity of (−)-(1R,5R,9R)- and (+)-(1S,5S,9S)-N-Alkenyl-, -N-Alkynyl-, and -N-Cyanoalkyl-5,9-dimethyl-2‘-hydroxy-6,7-benzomorphan Homologues von May, Everette L, Jacobson, Arthur E, Mattson, Mariena V, Traynor, John R, Woods, James H, Harris, Louis S, Bowman, Edward R, Aceto, Mario D

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Binding of β-carbolines and related agents at serotonin (5-HT 2 and 5-HT 1A), dopamine (D 2) and benzodiazepine receptors von Glennon, Richard A., Dukat, Malgorzata, Grella, Brian, Hong, Seoung-Soo, Costantino, Luca, Teitler, Milt, Smith, Carol, Egan, Chris, Davis, Katherine, Mattson, Mariena V.

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Antipodal .alpha.-N-(Methyl through Decyl)-N-normetazocines (5,9.alpha.-Dimethyl-2'-hydroxy-6,7-benzomorphans): In vitro and In vivo Properties von May, Everette L, Aceto, Mario D, Bowman, Edward R, Bentley, Christine, Martin, Billy R, Harris, Louis S, Medzihradsky, Fedor, Mattson, Mariena V, Jacobson, Arthur E

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A Marked Change of Receptor Affinity of the 2-Methyl-5-(3-hydroxyphenyl)morphans upon Attachment of an (E)-8-Benzylidene Moiety: Synthesis and Evaluation of a New Class of .sigma.... von Bertha, Craig M, Mattson, Mariena V, Flippen-Anderson, Judith L, Rothman, Richard B, Xu, Heng, Cha, Xian-Yuan, Becketts, Karen, Rice, Kenner C

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Zipeprol: preclinical assessment of abuse potential von Acteo, M.D., Bowman, E., Butelman, E., English, J.A., Harris, L., Jacobson, A.E., Mattson, M.V., Medzihradsky, F., Patrick, G., Rowlett, J.K., Smith, C.B., Winger, G., Woods, J.H., Woolverton, W.L.

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Synthesis and anticonvulsant activity of 1-phenylcyclohexylamine analogs von Thurkauf, Andrew, De Costa, Brian, Yamaguchi, Shunichi, Mattson, Mariena V, Jacobson, Arthur E, Rice, Kenner C, Rogawski, Michael A

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Analogs of the dioxolanes dexoxadrol and etoxadrol as potential phencyclidine-like agents. Synthesis and structure activity relationships von Thurkauf, Andrew, Mattson, Mariena V, Richardson, Scott, Mirsadeghi, Seid, Ornstein, Paul L, Harrison, Ernest A, Rice, Kenner C, Jacobson, Arthur E, Monn, James A

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Synthesis and structure-activity relationship of C5-substituted analogs of (.+-.)-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5, 10-imine [(.+-.)-desmethyl-MK801]: ligands for the NMD... von Monn, James A, Thurkauf, Andrew, Mattson, Mariena V, Jacobson, Arthur E, Rice, Kenner C

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Antagonism of Phencyclidine Action by Metaphit in Rat Cerebellar Purkinje Neurons: An Electrophysiological Study von Wang, Yun, Palmer, Michael, Freedman, Robert, Hoffer, Barry, Mattson, Mariena V., Lessor, Ralph A., Rice, Kenner C., Jacobson, Arthur E.

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Synthesis, stereochemistry, and biological activity of the 1-(1-phenyl-2-methylcyclohexyl)piperidines and the 1-(1-phenyl-4-methylcyclohexyl)piperidines. Absolute configuration of... von Iorio, Maria A, Tomassini, Lamberto, Mattson, Mariena V, George, Clifford, Jacobson, Arthur E

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Excitatory amino acid antagonists induce a phencyclidine-like catalepsy in pigeons: Structure-activity studies von Koek, W., Woods, J.H., Mattson, M.V., Jacobson, A.E., Mudar, P.J.

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Synthesis, pharmacological action, and receptor binding affinity of the enantiomeric 1-(1-phenyl-3-methylcyclohexyl)piperidines von Thurkauf, Andrew, Hillery, Paul, Mattson, Mariena V, Jacobson, Arthur E, Rice, Kenner C

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Synthesis, absolute configuration, and molecular modeling study of etoxadrol, a potent phencyclidine-like agonist von Thurkauf, Andrew, Zenk, Paul C, Balster, Robert L, May, Everette L, George, Clifford, Carroll, F. Ivy, Mascarella, S. Wayne, Rice, Kenner C, Jacobson, Arthur E, Mattson, Mariena V

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Etoxadrol- meta-isothiocyanate: A potent, enantioselective, electrophilic affinity ligand for the phencyclidine-binding site von Thurkauf, Andrew, Mattson, Mariena V., Huguenin, Philip N., Rice, Kenner C., Jacobson, Arthur E.

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Synthesis and biological evaluation of 1-[1-(2-benzo[b]thienyl)cyclohexyl]piperidine homologues at dopamine-uptake and phencyclidine- and σ-binding sites von XIAO-SHU HE, RAYMON, L. P, MATTSON, M. V, ELDEFRAWI, M. E, DE COSTA, B. R

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Hexahydro-1H-1-pyrindines from acid rearrangement of 9-alkylidene-5-(m-methoxyphenyl)-2-methylmorphans. A new structural type of narcotic antagonists von AWAYA, H, MAY, E. L, ACETO, M. D, HARRIS, L. S, SILVERTON, J. V, RICE, K. C, MATTSON, M. V, JACOBSON, A. E

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Further studies of the structure-activity relationships of 1-[1-(2-benzo[b]thienyl)cyclohexyl]piperidine. Synthesis and evaluation of 1-(2-benzo[b]thienyl)-N,N-dialkylcyclohexylami... von He, Xiaoshu, Raymon, Lionel P, Mattson, Mariena V, Eldefrawi, Mohyee E, de Costa, Brian R

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Synthesis, configuration, and activity of isomeric 2-phenyl-2-(N-piperidinyl)bicyclo[3.1.0]hexanes at phencyclidine and .sigma. binding sites von De Costa, Brian R, Mattson, Mariena V, George, Clifford, Linders, Joannes T. M

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Synthesis and binding properties of MK-801 isothiocyanates; (+)-3-isothiocyanato-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine hydrochloride: a new, potent and selec... von Linders, Joannes T. M, Monn, James A, Mattson, Mariena V, George, Clifford, Jacobson, Arthur E, Rice, Kenner C

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Specificity of phencyclidine-like drugs and benzomorphan opiates for two high affinity phencyclidine binding sites in guinea pig brain von Reid, A.A., Mattson, M.V., de Costa, B.R., Thurkauf, A., Jacobson, A.E., Monn, J.A., Rice, K.C., Rothman, R.B.

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