Targeting Protein Kinases for Cancer Therapy von Matthews, David J, Gerritsen, Mary E

Volltext

Glycan Shifting on Hepatitis C Virus (HCV) E2 Glycoprotein Is a Mechanism for Escape from Broadly Neutralizing Antibodies von Pantua, Homer, Diao, Jingyu, Ultsch, Mark, Hazen, Meredith, Mathieu, Mary, McCutcheon, Krista, Takeda, Kentaro, Date, Shailesh, Cheung, Tommy K., Phung, Qui, Hass, Phil, Arnott, David, Hongo, Jo-Anne, Matthews, David J., Brown, Alex, Patel, Arvind H., Kelley, Robert F., Eigenbrot, Charles, Kapadia, Sharookh B.

Volltext

Toward a Hepatitis C Virus Vaccine: the Structural Basis of Hepatitis C Virus Neutralization by AP33, a Broadly Neutralizing Antibody von POTTER, Jane A, OWSIANKA, Ania M, JEFFERY, Nathan, MATTHEWS, David J, KECK, Zhen-Yong, LAU, Patrick, FOUNG, Steven K. H, TAYLOR, Garry L, PATEL, Arvind H

Volltext

The Selective PI3K Inhibitor XL147 (SAR245408) Inhibits Tumor Growth and Survival and Potentiates the Activity of Chemotherapeutic Agents in Preclinical Tumor Models von Foster, Paul, Yamaguchi, Kyoko, Hsu, Pin P, Qian, Fawn, Du, Xiangnan, Wu, Jianming, Won, Kwang-Ai, Yu, Peiwen, Jaeger, Christopher T, Zhang, Wentao, Marlowe, Charles K, Keast, Paul, Abulafia, Wendy, Chen, Jason, Young, Jenny, Plonowski, Artur, Yakes, F Michael, Chu, Felix, Engell, Kelly, Bentzien, Frauke, Lam, Sanh T, Dale, Stephanie, Yturralde, Olivia, Matthews, David J, Lamb, Peter, Laird, A Douglas

Volltext

EXEL-7647 Inhibits Mutant Forms of ErbB2 Associated with Lapatinib Resistance and Neoplastic Transformation von TROWE, Torsten, BOUKOUVALA, Sotiria, VYSOTSKAIA, Valentina, JING PING YANG, GERRITSEN, Mary E, MATTHEWS, David J, LAMB, Peter, HEUER, Timothy S, CALKINS, Keith, CUTLER, Richard E, FONG, Ryan, FUNKE, Roel, GENDREAU, Steven B, KIM, Yong D, MILLER, Nicole, WOOLFREY, John R

Volltext

Pharmacological Abrogation of S-Phase Checkpoint Enhances the Anti-Tumor Activity of Gemcitabine In Vivo von Matthews, David J., Yakes, Michael, Chen, Jason, Tadano, Michele, Bornheim, Lester, Clary, Douglas O., Tai, Albert, Wagner, Jill M., Miller, Nicole, Kim, Yong D., Robertson, Scott, Murray, Louis, Karnitz, Larry M.

Volltext

Structures of Active and Latent PAI-1:  A Possible Stabilizing Role for Chloride Ions von Stout, Thomas J, Graham, Hugh, Buckley, Douglas I, Matthews, David J

Volltext

Substrate Phage: Selection of Protease Substrates by Monovalent Phage Display von Matthews, David J., Wells, James A.

Volltext

Characterization of the activity of the PI3K/mTOR inhibitor XL765 (SAR245409) in tumor models with diverse genetic alterations affecting the PI3K pathway von Yu, Peiwen, Laird, A Douglas, Du, Xiangnan, Wu, Jianming, Won, Kwang-Ai, Yamaguchi, Kyoko, Hsu, Pin Pin, Qian, Fawn, Jaeger, Christopher T, Zhang, Wentao, Buhr, Chris A, Shen, Paula, Abulafia, Wendy, Chen, Jason, Young, Jenny, Plonowski, Arthur, Yakes, F Michael, Chu, Felix, Lee, Michelle, Bentzien, Frauke, Lam, Sanh Tan, Dale, Stephanie, Matthews, David J, Lamb, Peter, Foster, Paul

Volltext

IL-9-Deficient Mice Establish Fundamental Roles for IL-9 in Pulmonary Mastocytosis and Goblet Cell Hyperplasia but Not T Cell Development von Townsend, Michael J, Fallon, Padraic G, Matthews, David J, Smith, Philip, Jolin, Helen E, McKenzie, Andrew N.J

Volltext

Efficiency of signalling through cytokine receptors depends critically on receptor orientation von Syed, Rashid S, Reid, Scott W, Li, Cuiwei, Cheetham, Janet C, Aoki, Kenneth H, Liu, Beishan, Zhan, Hangjun, Osslund, Timothy D, Chirino, Arthur J, Zhang, Jiandong, Finer-Moore, Janet, Elliott, Steven, Sitney, Karen, Katz, Bradley A, Matthews, David J, Wendoloski, John J, Egrie, Joan, Stroud, Robert M

Volltext

Biological characterization of SN32976, a selective inhibitor of PI3K and mTOR with preferential activity to PI3Kα, in comparison to established pan PI3K inhibitors von Rewcastle, Gordon W, Kolekar, Sharada, Buchanan, Christina M, Gamage, Swarna A, Giddens, Anna C, Tsang, Kit Y, Kendall, Jackie D, Singh, Ripudaman, Lee, Woo-Jeong, Smith, Greg C, Han, Weiping, Matthews, David J, Denny, William A, Shepherd, Peter R, Jamieson, Stephen M F

Volltext

Biological activity of IL-4 and IL-13 on human endothelial cells: functional evidence that both cytokines act through the same receptor von Kotowicz, Karolena, Callard, Robin E., Friedrich, Karlheinz, Matthews, David J., Klein, Nigel

Volltext

Fabrication of a Flexible Amperometric Glucose Sensor Using Additive Processes von Du, Xiaosong, Durgan, Christopher J., Matthews, David J., Motley, Joshua R., Tan, Xuebin, Pholsena, Kovit, Árnadóttir, Líney, Castle, Jessica R., Jacobs, Peter G., Cargill, Robert S., Ward, W. Kenneth, Conley, John F., Herman, Gregory S.

Volltext

Pyrazolopyrimidines as dual Akt/p70S6K inhibitors von Rice, Kenneth D., Kim, Moon H., Bussenius, Joerg, Anand, Neel K., Blazey, Charles M., Bowles, Owen J., Canne-Bannen, Lynne, Chan, Diva S.-M., Chen, Baili, Co, Erick W., Costanzo, Simona, DeFina, Steven C., Dubenko, Larisa, Engst, Stefan, Franzini, Maurizio, Huang, Ping, Jammalamadaka, Vasu, Khoury, Richard G., Klein, Rhett R., Laird, A.Douglas, Le, Donna T., Mac, Morrison B., Matthews, David J., Markby, David, Miller, Nicole, Nuss, John M., Parks, Jason J., Tsang, Tsze H., Tsuhako, Amy L., Wang, Yong, Xu, Wei

Volltext

Design and evaluation of a series of pyrazolopyrimidines as p70S6K inhibitors von Bussenius, Joerg, Anand, Neel K., Blazey, Charles M., Bowles, Owen J., Bannen, Lynne Canne, Chan, Diva S.-M., Chen, Baili, Co, Erick W., Costanzo, Simona, DeFina, Steven C., Dubenko, Larisa, Engst, Stefan, Franzini, Maurizio, Huang, Ping, Jammalamadaka, Vasu, Khoury, Richard G., Kim, Moon H., Klein, Rhett R., Laird, Douglas, Le, Donna T., Mac, Morrison B., Matthews, David J., Markby, David, Miller, Nicole, Nuss, John M., Parks, Jason J., Tsang, Tsze H., Tsuhako, Amy L., Wang, Yong, Xu, Wei, Rice, Kenneth D.

Volltext

IL-13 Is a Susceptibility Factor for Leishmania major Infection von Matthews, David J, Emson, Claire L, McKenzie, Grahame J, Jolin, Helen E, Blackwell, Jenefer M, McKenzie, Andrew N. J

Volltext

Screening the wetland plant species Alisma plantago-aquatica, Carex rostrata and Phalaris arundinacea for innate tolerance to zinc and comparison with Eriophorum angustifolium and... von Matthews, David J., Moran, Bridget M., Otte, Marinus L.

Volltext

Final Moments. I. Precursor Emission, Envelope Inflation, and Enhanced Mass Loss Preceding the Luminous Type II Supernova 2020tlf von Jacobson-Galán, W. V., Dessart, L., Jones, D. O., Margutti, R., Coppejans, D. L., Dimitriadis, G., Foley, R. J., Kilpatrick, C. D., Matthews, D. J., Rest, S., Terreran, G., Aleo, P. D., Auchettl, K., Blanchard, P. K., Coulter, D. A., Davis, K. W., de Boer, T. J. L., DeMarchi, L., Drout, M. R., Earl, N., Gagliano, A., Gall, C., Hjorth, J., Huber, M. E., Ibik, A. L., Milisavljevic, D., Pan, Y.-C., Rest, A., Ridden-Harper, R., Rojas-Bravo, C., Siebert, M. R., Smith, K. W., Taggart, K., Tinyanont, S., Wang, Q., Zenati, Y.

Volltext

Using model-system genetics for drug-based target discovery von Matthews, David J., Kopczynski, Jenny

Volltext