A conserved folding nucleus sculpts the free energy landscape of bacterial and archaeal orthologs from a divergent TIM barrel family von Jain, Rohit, Muneeruddin, Khaja, Anderson, Jeremy, Harms, Michael J., Shaffer, Scott A., Matthews, C. Robert

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Frustration and folding of a TIM barrel protein von Halloran, Kevin T., Wang, Yanming, Arora, Karunesh, Chakravarthy, Srinivas, Irving, Thomas C., Bilsel, Osman, Brooks, Charles L., Matthews, C. Robert

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Networks of electrostatic and hydrophobic interactions modulate the complex folding free energy surface of a designed βα protein von Basak, Sujit, Nobrega, R. Paul, Tavella, Davide, Deveau, Laura M., Koga, Nobuyasu, Tatsumi-Koga, Rie, Baker, David, Massi, Francesca, Matthews, C. Robert

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Trifluoroethanol Partially Unfolds G93A SOD1 Leading to Protein Aggregation: A Study by Native Mass Spectrometry and FPOP Protein Footprinting von Niu, Ben, Mackness, Brian C, Zitzewitz, Jill A, Matthews, C. Robert, Gross, Michael L

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Correlation of fitness landscapes from three orthologous TIM barrels originates from sequence and structure constraints von Chan, Yvonne H., Venev, Sergey V., Zeldovich, Konstantin B., Matthews, C. Robert

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Nonnative structure in a peptide model of the unfolded state of superoxide dismutase 1 (SOD1): Implications for ALS-linked aggregation von Cohen, Noah R., Zitzewitz, Jill A., Bilsel, Osman, Matthews, C. Robert

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Clusters of isoleucine, leucine, and valine side chains define cores of stability in high‐energy states of globular proteins: Sequence determinants of structure and stability von Kathuria, Sagar V., Chan, Yvonne H., Nobrega, R. Paul, Özen, Ayşegül, Matthews, C. Robert

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Toward a sustainable biomedical research enterprise: Finding consensus and implementing recommendations von Pickett, Christopher L, Benjamin W. Corb, C. Robert Matthews, Wesley I. Sundquist, Jeremy M. Berg

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Microsecond Barrier-Limited Chain Collapse Observed by Time-Resolved FRET and SAXS von Kathuria, Sagar V., Kayatekin, Can, Barrea, Raul, Kondrashkina, Elena, Graceffa, Rita, Guo, Liang, Nobrega, R. Paul, Chakravarthy, Srinivas, Matthews, C. Robert, Irving, Thomas C., Bilsel, Osman

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Folding of the RNA Recognition Motif (RRM) Domains of the Amyotrophic Lateral Sclerosis (ALS)-linked Protein TDP-43 Reveals an Intermediate State von Mackness, Brian C., Tran, Meme T., McClain, Shannan P., Matthews, C. Robert, Zitzewitz, Jill A.

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Metal Deficiency Increases Aberrant Hydrophobicity of Mutant Superoxide Dismutases That Cause Amyotrophic Lateral Sclerosis von Tiwari, Ashutosh, Liba, Amir, Sohn, Se Hui, Seetharaman, Sai V., Bilsel, Osman, Matthews, C.Robert, Hart, P.John, Valentine, Joan Selverstone, Hayward, Lawrence J.

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Analysis of Kinetics Using a Hybrid Maximum-Entropy/Nonlinear-Least-Squares Method: Application to Protein Folding von Steinbach, Peter J., Ionescu, Roxana, Matthews, C. Robert

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Metal-free ALS variants of dimeric human Cu,Zn-superoxide dismutase have enhanced populations of monomeric species von Svensson, Anna-Karin E, Bilsel, Osman, Kayatekin, Can, Adefusika, Jessica A, Zitzewitz, Jill A, Matthews, C Robert

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Disulfide-Reduced ALS Variants of Cu, Zn Superoxide Dismutase Exhibit Increased Populations of Unfolded Species von Kayatekin, Can, Zitzewitz, Jill A., Matthews, C. Robert

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Non-Native Structure Appears in Microseconds during the Folding of E. coli RNase H von Rosen, Laura E., Kathuria, Sagar V., Matthews, C. Robert, Bilsel, Osman, Marqusee, Susan

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Advances in turbulent mixing techniques to study microsecond protein folding reactions von Kathuria, Sagar V., Chan, Alexander, Graceffa, Rita, Paul Nobrega, R., Robert Matthews, C., Irving, Thomas C., Perot, Blair, Bilsel, Osman

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Microsecond acquisition of heterogeneous structure in the folding of a TIM barrel protein von Wu, Ying, Kondrashkina, Elena, Kayatekin, Can, Matthews, C. Robert, Bilsel, Osman

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Microsecond Subdomain Folding in Dihydrofolate Reductase von Arai, Munehito, Iwakura, Masahiro, Matthews, C. Robert, Bilsel, Osman

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Modulation of frustration in folding by sequence permutation von Nobrega, R. Paul, Arora, Karunesh, Kathuria, Sagar V., Graceffa, Rita, Barrea, Raul A., Guo, Liang, Chakravarthy, Srinivas, Bilsel, Osman, Irving, Thomas C., Brooks, Charles L., Matthews, C. Robert

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Clusters of Branched Aliphatic Side Chains Serve As Cores of Stability in the Native State of the HisF TIM Barrel Protein von Gangadhara, Basavanapura N., Laine, Jennifer M., Kathuria, Sagar V., Massi, Francesca, Matthews, C. Robert

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