Biocatalysis in the Pharmaceutical Industry: The Need for Speed von Truppo, Matthew D

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Development of an Immobilized Ketoreductase for Enzymatic (R)‑1-(3,5-Bis(trifluoromethyl)phenyl)ethanol Production von Li, Hongmei, Moncecchi, Johannah, Truppo, Matthew D

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Enzyme-Catalyzed Enantioselective Diaryl Ketone Reductions von Truppo, Matthew D, Pollard, David, Devine, Paul

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Development of an Immobilized Transaminase Capable of Operating in Organic Solvent von Truppo, Matthew D., Strotman, Hallena, Hughes, Gregory

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Biocatalysis enters a new era von Turner, Nicholas J, Truppo, Matthew D

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Efficient Production of Enantiomerically Pure Chiral Amines at Concentrations of 50 g/L Using Transaminases von Truppo, Matthew D, Rozzell, J. David, Turner, Nicholas J

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Efficient kinetic resolution of racemic amines using a transaminase in combination with an amino acid oxidase von Truppo, Matthew D, Turner, Nicholas J, Rozzell, J David

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Rapid screening and scale-up of transaminase catalysed reactions von Truppo, Matthew D, Rozzell, J David, Moore, Jeffrey C, Turner, Nicholas J

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“Site and Mutation”-Specific Predictions Enable Minimal Directed Evolution Libraries von Moore, Jeffrey C, Rodriguez-Granillo, Agustina, Crespo, Alejandro, Govindarajan, Sridhar, Welch, Mark, Hiraga, Kaori, Lexa, Katrina, Marshall, Nicholas, Truppo, Matthew D

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The importance of synthetic chemistry in the pharmaceutical industry von Campos, Kevin R., Coleman, Paul J., Alvarez, Juan C., Dreher, Spencer D., Garbaccio, Robert M., Terrett, Nicholas K., Tillyer, Richard D., Truppo, Matthew D., Parmee, Emma R.

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Development of an Improved Immobilized CAL-B for the Enzymatic Resolution of a Key Intermediate to Odanacatib von Truppo, Matthew D, Hughes, Gregory

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Micro-scale process development of transaminase catalysed reactions von Truppo, Matthew D, Turner, Nicholas J

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A fast and sensitive assay for measuring the activity and enantioselectivity of transaminases von Hopwood, Jennifer, Truppo, Matthew D, Turner, Nicholas J, Lloyd, Richard C

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Rapid Determination of Both the Activity and Enantioselectivity of Ketoreductases von Truppo, Matthew D, Escalettes, Franck, Turner, Nicholas J

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Bifunctional molecules targeting SARS-CoV-2 spike and the polymeric Ig receptor display neutralization activity and mucosal enrichment von White, Ian, Tamot, Ninkka, Doddareddy, Rajitha, Ho, Jason, Jiao, Qun, Harvilla, Paul B., Yang, Tong-Yuan, Geist, Brian, Borrok, M. Jack, Truppo, Matthew D., Ganesan, Rajkumar, Chowdhury, Partha, Zwolak, Adam

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Copper-Catalyzed Synthesis of Enantioenriched Tetraarylethanes von Jen, Wendy S, Truppo, Matthew D, Amos, Deborah, Devine, Paul, McNevin, Michael, Biba, Mirlinda, Campos, Kevin R

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Extending the application of biocatalysis to meet the challenges of drug development von Devine, Paul N., Howard, Roger M., Kumar, Rajesh, Thompson, Matthew P., Truppo, Matthew D., Turner, Nicholas J.

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Optimization and Scale-Up of a Lipase-Catalyzed Enzymatic Resolution of an Indole Ester Intermediate for a Prostaglandin D2 (DP) Receptor Antagonist Targeting Allergic Rhinitis von Truppo, Matthew D, Journet, Michel, Shafiee, Ali, Moore, Jeffrey C

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A Highly Efficient Asymmetric Synthesis of Vernakalant von Limanto, John, Ashley, Eric R, Yin, Jingjun, Beutner, Gregory L, Grau, Brendan T, Kassim, Amude M, Kim, Mary M, Klapars, Artis, Liu, Zhijian, Strotman, Hallena R, Truppo, Matthew D

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A generic platform for the immobilisation of engineered biocatalysts von Thompson, Matthew P., Derrington, Sasha R., Heath, Rachel S., Porter, Joanne L., Mangas-Sanchez, Juan, Devine, Paul N., Truppo, Matthew D., Turner, Nicholas J.

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