Selective Tumor Hypoxia Targeting by Hypoxia-Activated Prodrug TH-302 Inhibits Tumor Growth in Preclinical Models of Cancer von SUN, Jessica D, QIAN LIU, HART, Charles P, JINGLI WANG, AHLUWALIA, Dharmendra, FERRARO, Damien, YAN WANG, DUAN, Jian-Xin, STEVE AMMONS, W, CURD, John G, MATTEUCCI, Mark D

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Molecular and cellular pharmacology of the hypoxia-activated prodrug TH-302 von Meng, Fanying, Evans, James W, Bhupathi, Deepthi, Banica, Monica, Lan, Leslie, Lorente, Gustavo, Duan, Jian-Xin, Cai, Xiaohong, Mowday, Alexandra M, Guise, Christopher P, Maroz, Andrej, Anderson, Robert F, Patterson, Adam V, Stachelek, Gregory C, Glazer, Peter M, Matteucci, Mark D, Hart, Charles P

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Comparison of hypoxia-activated prodrug evofosfamide (TH-302) and ifosfamide in preclinical non-small cell lung cancer models von Sun, Jessica D., Liu, Qian, Ahluwalia, Dharmendra, Ferraro, Damien J., Wang, Yan, Jung, Don, Matteucci, Mark D., Hart, Charles P.

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TH-302, a hypoxia-activated prodrug with broad in vivo preclinical combination therapy efficacy: optimization of dosing regimens and schedules von Liu, Qian, Sun, Jessica D., Wang, Jingli, Ahluwalia, Dharmendra, Baker, Amanda F., Cranmer, Lee D., Ferraro, Damien, Wang, Yan, Duan, Jian-Xin, Ammons, W. Steve, Curd, John G., Matteucci, Mark D., Hart, Charles P.

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Potent and Highly Selective Hypoxia-Activated Achiral Phosphoramidate Mustards as Anticancer Drugs von Duan, Jian-Xin, Jiao, Hailong, Kaizerman, Jacob, Stanton, Timothy, Evans, James W, Lan, Leslie, Lorente, Gustavo, Banica, Monica, Jung, Don, Wang, Jinwei, Ma, Huaiyu, Li, Xiaoming, Yang, Zhijian, Hoffman, Robert M, Ammons, W. Steve, Hart, Charles P, Matteucci, Mark

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Enhancement of hypoxia-activated prodrug TH-302 anti-tumor activity by Chk1 inhibition von Meng, Fanying, Bhupathi, Deepthi, Sun, Jessica D, Liu, Qian, Ahluwalia, Dharmendra, Wang, Yan, Matteucci, Mark D, Hart, Charles P

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Potent Antitubulin Tumor Cell Cytotoxins Based on 3-Aroyl Indazoles von Duan, Jian-Xin, Cai, Xiaohong, Meng, Fanying, Lan, Leslie, Hart, Charles, Matteucci, Mark

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A Cytosine Analogue Capable of Clamp-Like Binding to a Guanine in Helical Nucleic Acids von Lin, Kuei-Ying, Matteucci, Mark D

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Combination treatment with hypoxia-activated prodrug evofosfamide (TH-302) and mTOR inhibitors results in enhanced antitumor efficacy in preclinical renal cell carcinoma models von Sun, Jessica D, Ahluwalia, Dharmendra, Liu, Qian, Li, Wenwu, Wang, Yan, Meng, Fanying, Bhupathi, Deepthi, Matteucci, Mark D, Hart, Charles P

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Current concepts in antisense drug design von Milligan, John F, Matteucci, Mark D, Martin, John C

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Nucleosides with a Twist. Can Fixed Forms of Sugar Ring Pucker Influence Biological Activity in Nucleosides and Oligonucleotides? von Marquez, Victor E, Siddiqui, Maqbool A, Ezzitouni, Abdallah, Russ, Pamela, Wang, Jianying, Wagner, Richard W, Matteucci, Mark D

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Antisense Gene Inhibition by Oligonucleotides Containing C-5 Propyne Pyrimidines von Wagner, Richard W., Matteucci, Mark D., Lewis, Jason G., Gutierrez, Arnold J., Moulds, Courtney, Froehler, Brian C.

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A novel class of tubulin inhibitors that exhibit potent antiproliferation and in vitro vessel-disrupting activity von Meng, Fanying, Cai, Xiaohong, Duan, Jianxin, Matteucci, Mark G., Hart, Charles P.

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Potent and selective inhibition of gene expression by an antisense heptanucleotide von Wagner, Richard W, Matteucci, Mark D, Grant, Deborah, Huang, Teresa, Froehler, Brian C

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Pheochromocytoma in dogs: 61 cases (1984-1995) von Barthez, P.Y, Marks, S.L, Woo, J, Feldman, E.C, Matteucci, M

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Hyperthermia Increases Accumulation of Technetium-99m-labeled Liposomes in Feline Sarcomas von MATTEUCCI, Mark L, ANYARAMBHATLA, Gopal, ROSNER, Gary, AZUMA, Chieko, FISHER, Paul E, DEWHIRST, Mark W, NEEDHAM, David, THRALL, Donald E

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Cellular penetration and antisense activity by a phenoxazine-substituted heptanucleotide von Flanagan, W. Michael, Matteucci, Mark D, Wagner, Richard W, Grant, Deborah, Lin, Kuei-Ying

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Synthesis and hybridization study of a boranophosphate-linked oligothymidine deoxynucleotide von Zhang, Jiancun, Terhorst, Terry, Matteucci, Mark D

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A Cytosine Analog That Confers Enhanced Potency to Antisense Oligonucleotides von Flanagan, W. Michael, Wolf, John J., Olson, Peter, Grant, Debbie, Lin, Kuei-Ying, Wagner, Richard W., Matteucci, Mark D.

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Triplex Formation by Oligonucleotides Containing 5-(1-Propynyl)-2‘-deoxyuridine:  Decreased Magnesium Dependence and Improved Intracellular Gene Targeting von Lacroix, Laurent, Lacoste, Jérôme, Reddoch, James F, Mergny, Jean-Louis, Levy, Dan D, Seidman, Michael M, Matteucci, Mark D, Glazer, Peter M

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