Selective Tumor Hypoxia Targeting by Hypoxia-Activated Prodrug TH-302 Inhibits Tumor Growth in Preclinical Models of Cancer von SUN, Jessica D, QIAN LIU, HART, Charles P, JINGLI WANG, AHLUWALIA, Dharmendra, FERRARO, Damien, YAN WANG, DUAN, Jian-Xin, STEVE AMMONS, W, CURD, John G, MATTEUCCI, Mark D

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Molecular and cellular pharmacology of the hypoxia-activated prodrug TH-302 von Meng, Fanying, Evans, James W, Bhupathi, Deepthi, Banica, Monica, Lan, Leslie, Lorente, Gustavo, Duan, Jian-Xin, Cai, Xiaohong, Mowday, Alexandra M, Guise, Christopher P, Maroz, Andrej, Anderson, Robert F, Patterson, Adam V, Stachelek, Gregory C, Glazer, Peter M, Matteucci, Mark D, Hart, Charles P

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Comparison of hypoxia-activated prodrug evofosfamide (TH-302) and ifosfamide in preclinical non-small cell lung cancer models von Sun, Jessica D., Liu, Qian, Ahluwalia, Dharmendra, Ferraro, Damien J., Wang, Yan, Jung, Don, Matteucci, Mark D., Hart, Charles P.

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Enhancement of hypoxia-activated prodrug TH-302 anti-tumor activity by Chk1 inhibition von Meng, Fanying, Bhupathi, Deepthi, Sun, Jessica D, Liu, Qian, Ahluwalia, Dharmendra, Wang, Yan, Matteucci, Mark D, Hart, Charles P

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TH-302, a hypoxia-activated prodrug with broad in vivo preclinical combination therapy efficacy: optimization of dosing regimens and schedules von Liu, Qian, Sun, Jessica D., Wang, Jingli, Ahluwalia, Dharmendra, Baker, Amanda F., Cranmer, Lee D., Ferraro, Damien, Wang, Yan, Duan, Jian-Xin, Ammons, W. Steve, Curd, John G., Matteucci, Mark D., Hart, Charles P.

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Antisense Gene Inhibition by Oligonucleotides Containing C-5 Propyne Pyrimidines von Wagner, Richard W., Matteucci, Mark D., Lewis, Jason G., Gutierrez, Arnold J., Moulds, Courtney, Froehler, Brian C.

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Potent and selective inhibition of gene expression by an antisense heptanucleotide von Wagner, Richard W, Matteucci, Mark D, Grant, Deborah, Huang, Teresa, Froehler, Brian C

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Cellular penetration and antisense activity by a phenoxazine-substituted heptanucleotide von Flanagan, W. Michael, Matteucci, Mark D, Wagner, Richard W, Grant, Deborah, Lin, Kuei-Ying

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Synthesis and hybridization study of a boranophosphate-linked oligothymidine deoxynucleotide von Zhang, Jiancun, Terhorst, Terry, Matteucci, Mark D

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Combination treatment with hypoxia-activated prodrug evofosfamide (TH-302) and mTOR inhibitors results in enhanced antitumor efficacy in preclinical renal cell carcinoma models von Sun, Jessica D, Ahluwalia, Dharmendra, Liu, Qian, Li, Wenwu, Wang, Yan, Meng, Fanying, Bhupathi, Deepthi, Matteucci, Mark D, Hart, Charles P

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A Cytosine Analogue Capable of Clamp-Like Binding to a Guanine in Helical Nucleic Acids von Lin, Kuei-Ying, Matteucci, Mark D

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Current concepts in antisense drug design von Milligan, John F, Matteucci, Mark D, Martin, John C

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Nucleosides with a Twist. Can Fixed Forms of Sugar Ring Pucker Influence Biological Activity in Nucleosides and Oligonucleotides? von Marquez, Victor E, Siddiqui, Maqbool A, Ezzitouni, Abdallah, Russ, Pamela, Wang, Jianying, Wagner, Richard W, Matteucci, Mark D

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A Cytosine Analog That Confers Enhanced Potency to Antisense Oligonucleotides von Flanagan, W. Michael, Wolf, John J., Olson, Peter, Grant, Debbie, Lin, Kuei-Ying, Wagner, Richard W., Matteucci, Mark D.

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Oligonucleotides containing a covalent conformationally restricted phosphodiester analog for high-affinity triple helix formation: the riboacetal internucleotide linkage von Jones, Robert J, Swaminathan, S, Milligan, John F, Wadwani, Shalini, Froehler, Brian C, Matteucci, Mark D

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Synthesis and binding properties of pyrimidine oligodeoxynucleoside analogs containing neutral phosphodiester replacements: the formacetal and 3'-thioformacetal internucleoside lin... von Jones, Robert J, Lin, Kuei Ying, Milligan, John F, Wadwani, Shalini, Matteucci, Mark D

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An assessment of the antisense properties of RNase H-competent and steric-blocking oligomers von Bonham, Michele A., Brown, Stephen, Boyd, Ann L., Brown, Pamela H., Bruckenstein, David A., Hanvey, Jeffery C., Thomson, Stephen A., Pipe, Adrian, Hassman, Fred, Bisi, John E., Froehler, Brian C., Matteucci, Mark D., Wagner, Richard W., Noble, Stewart A., Babiss, Lee E.

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Triplex Formation by Oligonucleotides Containing 5-(1-Propynyl)-2‘-deoxyuridine:  Decreased Magnesium Dependence and Improved Intracellular Gene Targeting von Lacroix, Laurent, Lacoste, Jérôme, Reddoch, James F, Mergny, Jean-Louis, Levy, Dan D, Seidman, Michael M, Matteucci, Mark D, Glazer, Peter M

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Antisense Gene Inhibition by C-5-Substituted Deoxyuridine-Containing Oligodeoxynucleotides von Gutierrez, Arnold J, Matteucci, Mark D, Grant, Deborah, Matsumura, Sandra, Wagner, Richard W, Froehler, Brian C

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Site and Mechanism of Antisense Inhibition by C-5 Propyne Oligonucleotides von Moulds, Courtney, Lewis, Jason G, Froehler, Brian C, Grant, Deborah, Huang, Teresa, Milligan, John F, Matteucci, Mark D, Wagner, Richard W

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