CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil von Almqvist, Helena, Axelsson, Hanna, Jafari, Rozbeh, Dan, Chen, Mateus, André, Haraldsson, Martin, Larsson, Andreas, Molina, Daniel Martinez, Artursson, Per, Lundbäck, Thomas, Nordlund, Pär

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Identification of novel small molecules that inhibit STAT3-dependent transcription and function von Kolosenko, Iryna, Yu, Yasmin, Busker, Sander, Dyczynski, Matheus, Liu, Jianping, Haraldsson, Martin, Palm Apergi, Caroline, Helleday, Thomas, Tamm, Katja Pokrovskaja, Page, Brent D G, Grander, Dan

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Inhibition of the ubiquitin-proteasome system by an NQO1-activatable compound von Giovannucci, Tatiana A., Salomons, Florian A., Haraldsson, Martin, Elfman, Lotta H. M., Wickström, Malin, Young, Patrick, Lundbäck, Thomas, Eirich, Jürgen, Altun, Mikael, Jafari, Rozbeh, Gustavsson, Anna-Lena, Johnsen, John Inge, Dantuma, Nico P.

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A drug screening assay on cancer cells chronically adapted to acidosis von Pellegrini, Paola, Serviss, Jason T, Lundbäck, Thomas, Bancaro, Nicolo, Mazurkiewicz, Magdalena, Kolosenko, Iryna, Yu, Di, Haraldsson, Martin, D'Arcy, Padraig, Linder, Stig, De Milito, Angelo

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Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel von Zhang, Si Min, Paulin, Cynthia B.J., Shu, Huazhang, Yagüe-Capilla, Miriam, Michel, Maurice, Marttila, Petra, Ortis, Florian, Bwanika, Henri Colyn, Dirks, Christopher, Venkatram, Rajagopal Papagudi, Wiita, Elisée, Jemth, Ann-Sofie, Almlöf, Ingrid, Loseva, Olga, Hormann, Femke M., Koolmeister, Tobias, Linde, Erika, Lee, Sun, Llona-Minguez, Sabin, Haraldsson, Martin, Axelsson, Hanna, Strömberg, Kia, Homan, Evert J., Scobie, Martin, Lundbäck, Thomas, Helleday, Thomas, Rudd, Sean G.

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Discovery of a novel inhibitor of macropinocytosis with antiviral activity von Porebski, Bartlomiej, Christ, Wanda, Corman, Alba, Haraldsson, Martin, Barz, Myriam, Lidemalm, Louise, Häggblad, Maria, Ilmain, Juliana, Wright, Shane C., Murga, Matilde, Schlegel, Jan, Jarvius, Malin, Lapins, Maris, Sezgin, Erdinc, Bhabha, Gira, Lauschke, Volker M., Carreras-Puigvert, Jordi, Lafarga, Miguel, Klingström, Jonas, Hühn, Daniela, Fernandez-Capetillo, Oscar

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A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage von Ladds, Marcus J. G. W., van Leeuwen, Ingeborg M. M., Drummond, Catherine J., Chu, Su, Healy, Alan R., Popova, Gergana, Pastor Fernández, Andrés, Mollick, Tanzina, Darekar, Suhas, Sedimbi, Saikiran K., Nekulova, Marta, Sachweh, Marijke C. C., Campbell, Johanna, Higgins, Maureen, Tuck, Chloe, Popa, Mihaela, Safont, Mireia Mayoral, Gelebart, Pascal, Fandalyuk, Zinayida, Thompson, Alastair M., Svensson, Richard, Gustavsson, Anna-Lena, Johansson, Lars, Färnegårdh, Katarina, Yngve, Ulrika, Saleh, Aljona, Haraldsson, Martin, D’Hollander, Agathe C. A., Franco, Marcela, Zhao, Yan, Håkansson, Maria, Walse, Björn, Larsson, Karin, Peat, Emma M., Pelechano, Vicent, Lunec, John, Vojtesek, Borivoj, Carmena, Mar, Earnshaw, William C., McCarthy, Anna R., Westwood, Nicholas J., Arsenian-Henriksson, Marie, Lane, David P., Bhatia, Ravi, McCormack, Emmet, Laín, Sonia

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Enhanced cytotoxicity of a novel family of ATPase inhibitors in colorectal cancer cells with high NAT2 activity von Zhang, Xiaonan, Akcan, Ece, Correia, Mario, Rameika, Natallia, Kundu, Snehangshu, Stoimenov, Ivaylo, Rendo, Veronica, Eriksson, Anna U., Haraldsson, Martin, Globisch, Daniel, Sjöblom, Tobias

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Optimization of Tetrahydroindazoles as Inhibitors of Human Dihydroorotate Dehydrogenase and Evaluation of Their Activity and In Vitro Metabolic Stability von Popova, Gergana, Ladds, Marcus J. G. W, Johansson, Lars, Saleh, Aljona, Larsson, Johanna, Sandberg, Lars, Sahlberg, Sara Häggblad, Qian, Weixing, Gullberg, Hjalmar, Garg, Neeraj, Gustavsson, Anna-Lena, Haraldsson, Martin, Lane, David, Yngve, Ulrika, Lain, Sonia

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Structure-Guided Design of Novel Thiazolidine Inhibitors of O‑Acetyl Serine Sulfhydrylase from Mycobacterium tuberculosis von Poyraz, Ömer, Jeankumar, Variam Ullas, Saxena, Shalini, Schnell, Robert, Haraldsson, Martin, Yogeeswari, Perumal, Sriram, Dharmarajan, Schneider, Gunter

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Photo-physical characterization of high triplet yield brominated fluoresceins by transient state (TRAST) spectroscopy von Demirbay, Baris, Baryshnikov, Glib, Haraldsson, Martin, Piguet, Joachim, Ågren, Hans, Widengren, Jerker

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High-affinity recognition of the human C-reactive protein independent of phosphocholineElectronic supplementary information (ESI) available: 1H and 13C NMR spectra, mass spectra (H... von Yang, Jie, Gustavsson, Anna-Lena, Haraldsson, Martin, Karlsson, Göran, Norberg, Thomas, Baltzer, Lars

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Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage von Ladds, Marcus J. G. W., van Leeuwen, Ingeborg M. M., Drummond, Catherine J., Chu, Su, Healy, Alan R., Popova, Gergana, Fernández, Andrés Pastor, Mollick, Tanzina, Darekar, Suhas, Sedimbi, Saikiran K., Nekulova, Marta, Sachweh, Marijke C. C., Campbell, Johanna, Higgins, Maureen, Tuck, Chloe, Popa, Mihaela, Safont, Mireia Mayoral, Gelebart, Pascal, Fandalyuk, Zinayida, Thompson, Alastair M., Svensson, Richard, Gustavsson, Anna-Lena, Johansson, Lars, Färnegårdh, Katarina, Yngve, Ulrika, Saleh, Aljona, Haraldsson, Martin, D’Hollander, Agathe C. A., Franco, Marcela, Zhao, Yan, Håkansson, Maria, Walse, Björn, Larsson, Karin, Peat, Emma M., Pelechano, Vicent, Lunec, John, Vojtesek, Borivoj, Carmena, Mar, Earnshaw, William C., McCarthy, Anna R., Westwood, Nicholas J., Arsenian-Henriksson, Marie, Lane, David P., Bhatia, Ravi, McCormack, Emmet, Laín, Sonia

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Tandem Benzophenone Amino Pyridines, Potent and Selective Inhibitors of Human Leukotriene C4 Synthase von Kleinschmidt, Thea K., Haraldsson, Martin, Basavarajappa, Devaraj, Lundeberg, Erik, Thulasingam, Madhuranayaki, Ekoff, Maria, Fauland, Alexander, Lehmann, Christoph, Kahnt, Astrid S., Lindbom, Lennart, Haeggström, Jesper Z.

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Identification of a novel compound that simultaneously impairs the ubiquitin-proteasome system and autophagy von Giovannucci, Tatiana A., Salomons, Florian A., Stoy, Henriette, Herzog, Laura K., Xu, Shanshan, Qian, Weixing, Merino, Lara G., Gierisch, Maria E., Haraldsson, Martin, Lystad, Alf H., Uvell, Hanna, Simonsen, Anne, Gustavsson, Anna-Lena, Vallin, Michaela, Dantuma, Nico P.

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Abstract 5509: A drug-screening model to identify compounds active in cells under metabolic stress von Pellegrini, Paola, Haraldsson, Martin, Jenmalm Jensen, Annika, Lundbäck, Thomas, De Milito, Angelo

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Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress von Bonagas, Nadilly, Gustafsson, Nina M S, Henriksson, Martin, Marttila, Petra, Gustafsson, Robert, Wiita, Elisée, Borhade, Sanjay, Green, Alanna C, Vallin, Karl S A, Sarno, Antonio, Svensson, Richard, Göktürk, Camilla, Pham, Therese, Jemth, Ann-Sofie, Loseva, Olga, Cookson, Victoria, Kiweler, Nicole, Sandberg, Lars, Rasti, Azita, Unterlass, Judith E, Haraldsson, Martin, Andersson, Yasmin, Scaletti, Emma R, Bengtsson, Christoffer, Paulin, Cynthia B J, Sanjiv, Kumar, Abdurakhmanov, Eldar, Pudelko, Linda, Kunz, Ben, Desroses, Matthieu, Iliev, Petar, Färnegårdh, Katarina, Krämer, Andreas, Garg, Neeraj, Michel, Maurice, Häggblad, Sara, Jarvius, Malin, Kalderén, Christina, Jensen, Amanda Bögedahl, Almlöf, Ingrid, Karsten, Stella, Zhang, Si Min, Häggblad, Maria, Eriksson, Anders, Liu, Jianping, Glinghammar, Björn, Nekhotiaeva, Natalia, Klingegård, Fredrik, Koolmeister, Tobias, Martens, Ulf, Llona-Minguez, Sabin, Moulson, Ruth, Nordström, Helena, Parrow, Vendela, Dahllund, Leif, Sjöberg, Birger, Vargas, Irene L, Vo, Duy Duc, Wannberg, Johan, Knapp, Stefan, Krokan, Hans E, Arvidsson, Per I, Scobie, Martin, Meiser, Johannes, Stenmark, Pål, Berglund, Ulrika Warpman, Homan, Evert J, Helleday, Thomas

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Identification of inhibitors of Tartrate‐resistant acid phosphatase (TRAP/ACP5) activity by small‐molecule screening von Reithmeier, Anja, Lundbäck, Thomas, Haraldsson, Martin, Frank, Martin, Ek‐Rylander, Barbro, Nyholm, Per‐Georg, Gustavsson, Anna‐Lena, Andersson, Göran

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Membrane-depolarizing channel blockers induce selective glioma cell death by impairing nutrient transport and unfolded protein/amino acid responses von Niklasson, Mia, Maddalo, Ianluca, Sramkova, Zuzana, Mutlu, Ercan, Wee, Shimei, Sekyrova, Petra, Schmidt, Linnéa, Fritz, Nicolas, Dehnisch, Ivar, Kyriatzis, Gregorios, Krafcikova, Michaela, Carson, Brittany B, Feenstra, Jennifer M, Marinescu, Voichita D, Segerman, Anna, Haraldsson, Martin, Gustavsson, Anna Lena, Hammarström, Jars G J, Jenmalm Jensen, Annika, Uhrbom, Lene, Altelaar, A. F Maarten, Linnarsson, Sten, Uhlén, Per, Trantirek, Lukas, Vincent, C. Theresa, Nelander, Sven, Enger, Per Oyvind, Andang, Michael

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Glioblastoma cytotoxicity conferred through dual disruption of endolysosomal homeostasis by Vacquinol-1 von Kwak, Dongoh, Hammarström, Lars G J, Haraldsson, Martin, Ernfors, Patrik

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