Inhibition of the Hedgehog Pathway in Advanced Basal-Cell Carcinoma von Von Hoff, Daniel D, LoRusso, Patricia M, Rudin, Charles M, Reddy, Josina C, Yauch, Robert L, Tibes, Raoul, Weiss, Glen J, Borad, Mitesh J, Hann, Christine L, Brahmer, Julie R, Mackey, Howard M, Lum, Bertram L, Darbonne, Walter C, Marsters, James C, de Sauvage, Frederic J, Low, Jennifer A

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A paracrine requirement for hedgehog signalling in cancer von Yauch, Robert L., Gould, Stephen E., Scales, Suzie J., Tang, Tracy, Tian, Hua, Ahn, Christina P., Marshall, Derek, Fu, Ling, Januario, Thomas, Kallop, Dara, Nannini-Pepe, Michelle, Kotkow, Karen, Marsters, James C., Rubin, Lee L., de Sauvage, Frederic J.

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GDC-0449—A potent inhibitor of the hedgehog pathway von Robarge, Kirk D., Brunton, Shirley A., Castanedo, Georgette M., Cui, Yong, Dina, Michael S., Goldsmith, Richard, Gould, Stephen E., Guichert, Oivin, Gunzner, Janet L., Halladay, Jason, Jia, Wei, Khojasteh, Cyrus, Koehler, Michael F.T., Kotkow, Karen, La, Hank, LaLonde, Rebecca L., Lau, Kevin, Lee, Leslie, Marshall, Derek, Marsters, James C., Murray, Lesley J., Qian, Changgeng, Rubin, Lee L., Salphati, Laurent, Stanley, Mark S., Stibbard, John H.A., Sutherlin, Daniel P., Ubhayaker, Savita, Wang, Shumei, Wong, Susan, Xie, Minli

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Targeting Superficial or Nodular Basal Cell Carcinoma with Topically Formulated Small Molecule Inhibitor of Smoothened von TANG, Tracy, TANG, Jean Y, SHPALL, Elana, WU, Angela, RUBIN, Lee L, MARSTERS, James C, EPSTEIN, Ervin H, CARO, Ivor, DE SAUVAGE, Frederic J, DONGWEI LI, REICH, Mike, CALLAHAN, Christopher A, LING FU, YAUCH, Robert L, WANG, Frank, KOTKOW, Karen, CHANG, Kris S

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A Structure-Based Database of Antibody Variable Domain Diversity von Bond, Christopher J., Wiesmann, Christian, Marsters, James C., Sidhu, Sachdev S.

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Interplay of Dissolution, Solubility, and Nonsink Permeation Determines the Oral Absorption of the Hedgehog Pathway Inhibitor GDC-0449 in Dogs: An Investigation Using Preclinical S... von WONG, Harvey, THEIL, Frank-Peter, YUZHONG DENG, HOP, Cornelis E. C. A, YONG CUI, MARSTERS, James C, KHOJASTEH, S. Cyrus, VERNILLET, Laurent, LA, Hank, XILING SONG, HONG WANG, MORINELLO, Eric J

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Selective detection of membrane proteins without antibodies: a mass spectrometric version of the Western blot von Arnott, David, Kishiyama, Adrianne, Luis, Elizabeth A, Ludlum, Sarah G, Marsters, Jr, James C, Stults, John T

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Second generation 2-pyridyl biphenyl amide inhibitors of the hedgehog pathway von Castanedo, Georgette M., Wang, Shumei, Robarge, Kirk D., Blackwood, Elizabeth, Burdick, Daniel, Chang, Christine, Dijkgraaf, Gerrit J.P., Gould, Stephen, Gunzner, Janet, Guichert, Oivin, Halladay, Jason, Khojasteh, Cyrus, Lee, Leslie, Marsters, James C., Murray, Lesley, Peterson, David, Plise, Emile, Salphati, Laurent, de Sauvage, Frederic J., Wong, Susan, Sutherlin, Daniel P.

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CDK2/cyclinA inhibitors: Targeting the cyclinA recruitment site with small molecules derived from peptide leads von Castanedo, Georgette, Clark, Kevin, Wang, Shumei, Tsui, Vickie, Wong, Mengling, Nicholas, John, Wickramasinghe, Dineli, Marsters, James C., Sutherlin, Daniel

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Targeting Superficial or Nodular Basal Cell Carcinoma with Topically Formulated Small Molecule Inhibitor of Smoothened von Tang, Tracy, Tang, Jean Y, Li, Dongwei, Reich, Mike, Callahan, Christopher A, Fu, Ling, Yauch, Robert L, Wang, Frank, Kotkow, Karen, Chang, Kris S, Shpall, Elana, Wu, Angela, Rubin, Lee, Marsters, James C., Jr, Epstein, Ervin H., Jr, Caro, Ivor, de Sauvage, Frederic J

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Use of a Prenylation Inhibitor as a Novel Antiviral Agent von Glenn, J S, Marsters, Jr, J C, Greenberg, H B

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N-Benzoyl amino acids as ICAM/LFA-1 inhibitors. Part 2: Structure-activity relationship of the benzoyl moiety von BURDICK, Daniel J, MARSTERS, James C, ALIAGAS-MARTIN, Ignacio, STANLEY, Mark, BERESINI, Maureen, CLARK, Kevin, MCDOWELL, Robert S, GADEK, Thomas R

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Competition between intercellular adhesion molecule-1 and a small-molecule antagonist for a common binding site on the alphal subunit of lymphocyte function-associated antigen-1 von Keating, Susan M, Clark, Kevin R, Stefanich, Lisa D, Arellano, Fred, Edwards, Caroline P, Bodary, Sarah C, Spencer, Steven A, Gadek, Thomas R, Marsters, Jr, James C, Beresini, Maureen H

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Benzodiazeprine peptidomimetics: potent inhibitors of ras farnesylation in animal cells von James, Guy L, Goldstein, Joseph L, Brown, Michael S, Rawson, Thomas E, Somers, Todd C, McDowell, Robert S, Crowley, Craig W, Lucas, Brian K, Levinson, Arthur, Marsters, Jr., James C

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Tetrapeptide Inhibitors of Protein Farnesyltransferase: Amino-Terminal Substitution in Phenylalanine-Containing Tetrapeptides Restores Farnesylation von Brown, Michael S., Goldstein, Joseph L., Paris, Kenneth J., Burnier, John P., James C. Marsters, Jr

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Solid-phase synthesis of dual alpha4beta1/alpha4beta7 integrin antagonists: two scaffolds with overlapping pharmacophores von Castanedo, Georgette M, Sailes, Fredrick C, Dubree, Nathan J P, Nicholas, John B, Caris, Lisa, Clark, Kevin, Keating, Susan M, Beresini, Maureen H, Chiu, Henry, Fong, Sherman, Marsters, Jr, James C, Jackson, David Y, Sutherlin, Daniel P

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Selective Detection of Membrane Proteins Without Antibodies von Arnott, David, Kishiyama, Adrianne, Luis, Elizabeth A., Ludlum, Sarah G., Marsters, James C., Stults, John T.

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ChemInform Abstract: Synthesis of 3-Amino-1-carboxymethylbenzodiazepine (BZA) Peptidomimetics von Marsters Jr, James C., Rawson, Thomas E.

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PYRAZOLE INHIBITORS OF WNT SIGNALING von GUNZNER, Janet L, BRUNTON, Shirley Ann, COULTER, Tom, MARSTERS, JR., James C, STIBBARD, John H. A

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COMPOSITIONS AND METHODS FOR DETECTING AND QUANTIFYING GENE EXPRESSION von SMITH, VICTORIA, LOWE, DAVID, G, ROBBIE, EDWARD, P, MARSTERS JAMES, C., JR

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