Inhibition of the Hedgehog Pathway in Advanced Basal-Cell Carcinoma von Von Hoff, Daniel D, LoRusso, Patricia M, Rudin, Charles M, Reddy, Josina C, Yauch, Robert L, Tibes, Raoul, Weiss, Glen J, Borad, Mitesh J, Hann, Christine L, Brahmer, Julie R, Mackey, Howard M, Lum, Bertram L, Darbonne, Walter C, Marsters, James C, de Sauvage, Frederic J, Low, Jennifer A

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A paracrine requirement for hedgehog signalling in cancer von Yauch, Robert L., Gould, Stephen E., Scales, Suzie J., Tang, Tracy, Tian, Hua, Ahn, Christina P., Marshall, Derek, Fu, Ling, Januario, Thomas, Kallop, Dara, Nannini-Pepe, Michelle, Kotkow, Karen, Marsters, James C., Rubin, Lee L., de Sauvage, Frederic J.

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GDC-0449—A potent inhibitor of the hedgehog pathway von Robarge, Kirk D., Brunton, Shirley A., Castanedo, Georgette M., Cui, Yong, Dina, Michael S., Goldsmith, Richard, Gould, Stephen E., Guichert, Oivin, Gunzner, Janet L., Halladay, Jason, Jia, Wei, Khojasteh, Cyrus, Koehler, Michael F.T., Kotkow, Karen, La, Hank, LaLonde, Rebecca L., Lau, Kevin, Lee, Leslie, Marshall, Derek, Marsters, James C., Murray, Lesley J., Qian, Changgeng, Rubin, Lee L., Salphati, Laurent, Stanley, Mark S., Stibbard, John H.A., Sutherlin, Daniel P., Ubhayaker, Savita, Wang, Shumei, Wong, Susan, Xie, Minli

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Targeting Superficial or Nodular Basal Cell Carcinoma with Topically Formulated Small Molecule Inhibitor of Smoothened von TANG, Tracy, TANG, Jean Y, SHPALL, Elana, WU, Angela, RUBIN, Lee L, MARSTERS, James C, EPSTEIN, Ervin H, CARO, Ivor, DE SAUVAGE, Frederic J, DONGWEI LI, REICH, Mike, CALLAHAN, Christopher A, LING FU, YAUCH, Robert L, WANG, Frank, KOTKOW, Karen, CHANG, Kris S

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A Structure-Based Database of Antibody Variable Domain Diversity von Bond, Christopher J., Wiesmann, Christian, Marsters, James C., Sidhu, Sachdev S.

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Interplay of Dissolution, Solubility, and Nonsink Permeation Determines the Oral Absorption of the Hedgehog Pathway Inhibitor GDC-0449 in Dogs: An Investigation Using Preclinical S... von WONG, Harvey, THEIL, Frank-Peter, YUZHONG DENG, HOP, Cornelis E. C. A, YONG CUI, MARSTERS, James C, KHOJASTEH, S. Cyrus, VERNILLET, Laurent, LA, Hank, XILING SONG, HONG WANG, MORINELLO, Eric J

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Second generation 2-pyridyl biphenyl amide inhibitors of the hedgehog pathway von Castanedo, Georgette M., Wang, Shumei, Robarge, Kirk D., Blackwood, Elizabeth, Burdick, Daniel, Chang, Christine, Dijkgraaf, Gerrit J.P., Gould, Stephen, Gunzner, Janet, Guichert, Oivin, Halladay, Jason, Khojasteh, Cyrus, Lee, Leslie, Marsters, James C., Murray, Lesley, Peterson, David, Plise, Emile, Salphati, Laurent, de Sauvage, Frederic J., Wong, Susan, Sutherlin, Daniel P.

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Selective detection of membrane proteins without antibodies: a mass spectrometric version of the Western blot von Arnott, David, Kishiyama, Adrianne, Luis, Elizabeth A, Ludlum, Sarah G, Marsters, Jr, James C, Stults, John T

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CDK2/cyclinA inhibitors: Targeting the cyclinA recruitment site with small molecules derived from peptide leads von Castanedo, Georgette, Clark, Kevin, Wang, Shumei, Tsui, Vickie, Wong, Mengling, Nicholas, John, Wickramasinghe, Dineli, Marsters, James C., Sutherlin, Daniel

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VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism von Gerber, Hans-Peter, Malik, Ajay K, Solar, Gregg P, Sherman, Daniel, Liang, Xiao Huan, Meng, Gloria, Hong, Kyu, Marsters, James C, Ferrara, Napoleone

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N-Benzoyl amino acids as ICAM/LFA-1 inhibitors. Part 2: Structure-activity relationship of the benzoyl moiety von BURDICK, Daniel J, MARSTERS, James C, ALIAGAS-MARTIN, Ignacio, STANLEY, Mark, BERESINI, Maureen, CLARK, Kevin, MCDOWELL, Robert S, GADEK, Thomas R

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Use of a Prenylation Inhibitor as a Novel Antiviral Agent von Glenn, J S, Marsters, Jr, J C, Greenberg, H B

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N-Benzoyl amino acids as LFA-1/ICAM inhibitors 1: amino acid structure–activity relationship von Burdick, Daniel J., Paris, Ken, Weese, Kenneth, Stanley, Mark, Beresini, Maureen, Clark, Kevin, McDowell, Robert S., Marsters, James C., Gadek, Thomas R.

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Kinetics of iron(III) porphyrin catalyzed epoxidations von Traylor, Teddy G, Marsters, James C, Nakano, Taku, Dunlap, Beth E

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Synthesis, hybridization properties and antiviral activity of lipid-oligodeoxynucleotide conjugates von SHEA, R. G, MARSTERS, J. C, BISCHOFBERGER, N

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Competition between intercellular adhesion molecule-1 and a small-molecule antagonist for a common binding site on the alphal subunit of lymphocyte function-associated antigen-1 von Keating, Susan M, Clark, Kevin R, Stefanich, Lisa D, Arellano, Fred, Edwards, Caroline P, Bodary, Sarah C, Spencer, Steven A, Gadek, Thomas R, Marsters, Jr, James C, Beresini, Maureen H

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Benzodiazepine Peptidomimetics: Potent Inhibitors of Ras Farnesylation in Animal Cells von James, Guy L., Goldstein, Joseph L., Brown, Michael S., Rawson, Thomas E., Somers, Todd C., McDowell, Robert S., Crowley, Craig W., Lucas, Brian K., Levinson, Arthur D., Marsters, James C.

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Tetrapeptide Inhibitors of Protein Farnesyltransferase: Amino-Terminal Substitution in Phenylalanine-Containing Tetrapeptides Restores Farnesylation von Brown, Michael S., Goldstein, Joseph L., Paris, Kenneth J., Burnier, John P., James C. Marsters, Jr

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Contributions of CDR3 to VHH Domain Stability and the Design of Monobody Scaffolds for Naive Antibody Libraries von Bond, Christopher J., Marsters, James C., Sidhu, Sachdev S.

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Selective Detection of Membrane Proteins Without Antibodies von Arnott, David, Kishiyama, Adrianne, Luis, Elizabeth A., Ludlum, Sarah G., Marsters, James C., Stults, John T.

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