Evaluation of engineered AAV capsids for hepatic factor IX gene transfer in murine and canine models von Markusic, David M, Nichols, Timothy C, Merricks, Elizabeth P, Palaschak, Brett, Zolotukhin, Irene, Marsic, Damien, Zolotukhin, Sergei, Srivastava, Arun, Herzog, Roland W

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Engineering and In Vitro Selection of a Novel AAV3B Variant with High Hepatocyte Tropism and Reduced Seroreactivity von Biswas, Moanaro, Marsic, Damien, Li, Ning, Zou, Chenhui, Gonzalez-Aseguinolaza, Gloria, Zolotukhin, Irene, Kumar, Sandeep R.P., Rana, Jyoti, Butterfield, John S.S., Kondratov, Oleksandr, de Jong, Ype P., Herzog, Roland W., Zolotukhin, Sergei

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Parent-map: analysis of parental contributions to evolved or engineered protein or DNA sequences von Marsic, Damien

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High-accuracy biodistribution analysis of adeno-associated virus variants by double barcode sequencing von Marsic, Damien, Méndez-Gómez, Héctor R, Zolotukhin, Sergei

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An Immune-Competent Murine Model to Study Elimination of AAV-Transduced Hepatocytes by Capsid-Specific CD8 + T Cells von Palaschak, Brett, Marsic, Damien, Herzog, Roland W, Zolotukhin, Sergei, Markusic, David M

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Altering Tropism of rAAV by Directed Evolution von Marsic, Damien, Zolotukhin, Sergei

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304. Deriving Useful Data from Next-Gen Sequencing of AAV Capsid Libraries von Marsic, Damien, Zolotukhin, Sergei

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Thermococcus thioreducens sp. nov., a novel hyperthermophilic, obligately sulfur-reducing archaeon from a deep-sea hydrothermal vent von Pikuta, Elena V, Marsic, Damien, Itoh, Takashi, Bej, Asim K, Tang, Jane, Whitman, William B, Ng, Joseph D, Garriott, Owen K, Hoover, Richard B

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Direct Head-to-Head Evaluation of Recombinant Adeno-associated Viral Vectors Manufactured in Human versus Insect Cells von Kondratov, Oleksandr, Marsic, Damien, Crosson, Sean M., Mendez-Gomez, Hector R., Moskalenko, Oleksandr, Mietzsch, Mario, Heilbronn, Regine, Allison, Jonathan R., Green, Kari B., Agbandje-McKenna, Mavis, Zolotukhin, Sergei

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PCR-based gene synthesis to produce recombinant proteins for crystallization von Marsic, Damien, Hughes, Ronny C, Byrne-Steele, Miranda L, Ng, Joseph D

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Characterization of a bioengineered AAV3B capsid variant with enhanced hepatocyte tropism and immune evasion von Rana, Jyoti, Marsic, Damien, Zou, Chenhui, Melero, Maite Munoz, Li, Xin, Kondratov, Oleksandr, Li, Ning, de Yong, Ype, Zolotukhin, Sergei, Biswas, Moanaro

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264. Absence of CD8 T Cell Responses Against AAV Capsid Using Reduced Vector Dose or Library Selected Liver Targeted AAV2 Based Capsids von Palaschak, Brett, Marsic, Damien, Markusic, David M.

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Intravitreal injection of a rationally designed AAV capsid library in non-human primate identifies variants with enhanced retinal transduction and neutralizing antibody evasion von Kellish, Patrick C., Marsic, Damien, Crosson, Sean M., Choudhury, Shreyasi, Scalabrino, Miranda L., Strang, Christianne E., Hill, Julie, McCullough, K. Tyler, Peterson, James J., Fajardo, Diego, Gupte, Siddhant, Makal, Victoria, Kondratov, Oleksandr, Kondratova, Liudmyla, Iyer, Siva, Witherspoon, C. Douglas, Gamlin, Paul D., Zolotukhin, Sergei, Boye, Sanford L., Boye, Shannon E.

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Vector Design Tour de Force: Integrating Combinatorial and Rational Approaches to Derive Novel Adeno-associated Virus Variants von Marsic, Damien, Govindasamy, Lakshmanan, Currlin, Seth, Markusic, David M, Tseng, Yu-Shan, Herzog, Roland W, Agbandje-McKenna, Mavis, Zolotukhin, Sergei

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549. Fine Tuning of Transduction Efficiency of rAAV Vectors via Modulation of Capsid Composition von Kondratov, Oleksandr, Marsic, Damien, Mietzsch, Mario, Heilbronn, Regine, Zolotukhin, Sergei

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Identification of Novel Retinal Pericyte-Targeting rAAV Vectors Through Directed Evolution von Patel, Dwani D., Marsic, Damien, Periasamy, Ramesh, Zolotukhin, Sergei, Lipinski, Daniel M.

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Biodistribution and safety of a single rAAV3B-AAT vector for silencing and replacement of alpha-1 antitrypsin in Cynomolgus macaques von Blackwood, Meghan, Gruntman, Alisha M., Tang, Qiushi, Pires-Ferreira, Debora, Reil, Darcy, Kondratov, Oleksandr, Marsic, Damien, Zolotukhin, Sergei, Gernoux, Gwladys, Keeler, Allison M., Mueller, Christian, Flotte, Terence R.

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Flat mounts sample 4 von Marsic, Damien

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Flat mounts sample 5 von Marsic, Damien

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Sample identification von Marsic, Damien

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