RAS mutations drive proliferative chronic myelomonocytic leukemia via a KMT2A-PLK1 axis von Carr, Ryan M., Vorobyev, Denis, Lasho, Terra, Marks, David L., Tolosa, Ezequiel J., Vedder, Alexis, Almada, Luciana L., Yurcheko, Andrey, Padioleau, Ismael, Alver, Bonnie, Coltro, Giacomo, Binder, Moritz, Safgren, Stephanie L., Horn, Isaac, You, Xiaona, Solary, Eric, Balasis, Maria E., Berger, Kurt, Hiebert, James, Witzig, Thomas, Buradkar, Ajinkya, Graf, Temeida, Valent, Peter, Mangaonkar, Abhishek A., Robertson, Keith D., Howard, Matthew T., Kaufmann, Scott H., Pin, Christopher, Fernandez-Zapico, Martin E., Geissler, Klaus, Droin, Nathalie, Padron, Eric, Zhang, Jing, Nikolaev, Sergey, Patnaik, Mrinal M.

Volltext

Oncogenic gene expression and epigenetic remodeling of cis-regulatory elements in ASXL1-mutant chronic myelomonocytic leukemia von Binder, Moritz, Carr, Ryan M., Lasho, Terra L., Finke, Christy M., Mangaonkar, Abhishek A., Pin, Christopher L., Berger, Kurt R., Mazzone, Amelia, Potluri, Sandeep, Ordog, Tamas, Robertson, Keith D., Marks, David L., Fernandez-Zapico, Martin E., Gaspar-Maia, Alexandre, Patnaik, Mrinal M.

Volltext

Use of Bodipy-labeled sphingolipid and cholesterol analogs to examine membrane microdomains in cells von Marks, David L., Bittman, Robert, Pagano, Richard E.

Volltext

Rab proteins mediate Golgi transport of caveola-internalized glycosphingolipids and correct lipid trafficking in Niemann-Pick C cells von Choudhury, Amit, Dominguez, Michel, Puri, Vishwajeet, Sharma, Deepak K, Narita, Keishi, Wheatley, Christine L, Marks, David L, Pagano, Richard E

Volltext

Distinct mechanisms of clathrin-independent endocytosis have unique sphingolipid requirements von Cheng, Zhi-Jie, Singh, Raman Deep, Sharma, Deepak K, Holicky, Eileen L, Hanada, Kentaro, Marks, David L, Pagano, Richard E

Volltext

Selective caveolin-1-dependent endocytosis of glycosphingolipids von Singh, Raman Deep, Puri, Vishwajeet, Valiyaveettil, Jacob T, Marks, David L, Bittman, Robert, Pagano, Richard E

Volltext

Selective stimulation of caveolar endocytosis by glycosphingolipids and cholesterol von Sharma, Deepak K, Brown, Jennifer C, Choudhury, Amit, Peterson, Timothy E, Holicky, Eileen, Marks, David L, Simari, Robert, Parton, Robert G, Pagano, Richard E

Volltext

Nuclear Dynamics and Chromatin Structure: Implications for Pancreatic Cancer von Flores, Luis F, Tader, Brooke R, Tolosa, Ezequiel J, Sigafoos, Ashley N, Marks, David L, Fernandez-Zapico, Martin E

Volltext

Glycosphingolipids Internalized via Caveolar-related Endocytosis Rapidly Merge with the Clathrin Pathway in Early Endosomes and Form Microdomains for Recycling von Sharma, Deepak K, Choudhury, Amit, Singh, Raman Deep, Wheatley, Christine L, Marks, David L, Pagano, Richard E

Volltext

Elevated endosomal cholesterol levels in Niemann-Pick cells inhibit rab4 and perturb membrane recycling von Choudhury, Amit, Sharma, Deepak K, Marks, David L, Pagano, Richard E

Volltext

Epigenetics of gastrointestinal diseases: notes from a workshop von Marks, David L., Olson, Rachel L., Urrutia, Raul, Billadeau, Daniel D., Roy, Nilotpal, Calin, George A., Fabbri, Muller, Koutsioumpa, Marina, Iliopoulos, Dimitrios, Ordog, Tamas, Huebert, Robert, Sarmento, Olga, Bamidele, Adebowale O., Faubion, William, Lomberk, Gwen L., Siveke, Jens, Ahuja, Nita, Iovanna, Juan, Hlady, Ryan A., Robertson, Keith, Kisiel, John, Pin, Christopher L., Fernandez-Zapico, Martin E.

Volltext

Regulation of caveolar endocytosis by syntaxin 6-dependent delivery of membrane components to the cell surface von Pagano, Richard E, Choudhury, Amit, Marks, David L, Proctor, Kirsty M, Gould, Gwyn W

Volltext

The glycosphingolipid, lactosylceramide, regulates β1-integrin clustering and endocytosis von SHARMA, Deepak K, BROWN, Jennifer C, ZHIJIE CHENG, HOLICKY, Eileen L, MARKS, David L, PAGANO, Richard E

Volltext

Development of a Rab9 Transgenic Mouse and Its Ability to Increase the Lifespan of a Murine Model of Niemann-Pick Type C Disease von Kaptzan, Tatiana, West, Sally A, Holicky, Eileen L, Wheatley, Christine L, Marks, David L, Wang, Tengke, Peake, Kyle B, Vance, Jean, Walkley, Steven U, Pagano, Richard E

Volltext

Inhibition of caveolar uptake, SV40 infection, and β1-integrin signaling by a nonnatural glycosphingolipid stereoisomer von Singh, Raman Deep, Holicky, Eileen L, Cheng, Zhi-jie, Kim, Seong-Youl, Wheatley, Christine L, Marks, David L, Bittman, Robert, Pagano, Richard E

Volltext

Protein transduction of Rab9 in Niemann-Pick C cells reduces cholesterol storage von Narita, Keishi, Choudhury, Amit, Dobrenis, Kostantin, Sharma, Deepak K, Holicky, Eileen L, Marks, David L, Walkley, Steven U, Pagano, Richard E

Volltext

Caveolar Endocytosis and Microdomain Association of a Glycosphingolipid Analog Is Dependent on Its Sphingosine Stereochemistry von Singh, Raman Deep, Liu, Yidong, Wheatley, Christine L., Holicky, Eileen L., Makino, Asami, Marks, David L., Kobayashi, Toshihide, Subramaniam, Gopal, Bittman, Robert, Pagano, Richard E.

Volltext

Endocytosis and sorting of glycosphingolipids in sphingolipid storage disease von Marks, David L, Pagano, Richard E

Volltext

Epigenetic control of the tumor microenvironment von Marks, David L, Olson, Rachel LO, Fernandez-Zapico, Martin E

Volltext

GLI1/GLI2 functional interplay is required to control Hedgehog/GLI targets gene expression von Tolosa, Ezequiel J, Fernandez-Barrena, Maite G, Iguchi, Eriko, McCleary-Wheeler, Angela L, Carr, Ryan M, Almada, Luciana L, Flores, Luis F, Vera, Renzo E, Alfonse, Germine W, Marks, David L, Hogenson, Tara L, Vrabel, Anne M, Horn, Isaac P, Koenig, Amanda N, Safgren, Stephanie L, Sigafoos, Ashley N, Erkan, Mert, Romecin-Duran, Paola A, Sarabia Gonzalez, Alejandro, Zhou, Bo, Javelaud, Delphine, Marsaud, Veronique, Graham, Rondell P, Mauviel, Alain, Elsawa, Sherine F, Fernandez-Zapico, Martin E

Volltext