Circadian Reprogramming in the Liver Identifies Metabolic Pathways of Aging von Sato, Shogo, Solanas, Guiomar, Peixoto, Francisca Oliveira, Bee, Leonardo, Symeonidi, Aikaterini, Schmidt, Mark S., Brenner, Charles, Masri, Selma, Benitah, Salvador Aznar, Sassone-Corsi, Paolo

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A randomized placebo-controlled clinical trial of nicotinamide riboside in obese men: safety, insulin-sensitivity, and lipid-mobilizing effects von Dollerup, Ole L, Christensen, Britt, Svart, Mads, Schmidt, Mark S, Sulek, Karolina, Ringgaard, Steffen, Stødkilde-Jørgensen, Hans, Møller, Niels, Brenner, Charles, Treebak, Jonas T, Jessen, Niels

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Nicotinamide riboside is uniquely and orally bioavailable in mice and humans von Trammell, Samuel A. J., Schmidt, Mark S., Weidemann, Benjamin J., Redpath, Philip, Jaksch, Frank, Dellinger, Ryan W., Li, Zhonggang, Abel, E. Dale, Migaud, Marie E., Brenner, Charles

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Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity von Heer, Collin D., Sanderson, Daniel J., Voth, Lynden S., Alhammad, Yousef M.O., Schmidt, Mark S., Trammell, Samuel A.J., Perlman, Stanley, Cohen, Michael S., Fehr, Anthony R., Brenner, Charles

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NAD+ Controls Circadian Reprogramming through PER2 Nuclear Translocation to Counter Aging von Levine, Daniel C., Hong, Heekyung, Weidemann, Benjamin J., Ramsey, Kathryn M., Affinati, Alison H., Schmidt, Mark S., Cedernaes, Jonathan, Omura, Chiaki, Braun, Rosemary, Lee, Choogon, Brenner, Charles, Peek, Clara Bien, Bass, Joseph

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Niacin Cures Systemic NAD+ Deficiency and Improves Muscle Performance in Adult-Onset Mitochondrial Myopathy von Pirinen, Eija, Auranen, Mari, Khan, Nahid A., Brilhante, Virginia, Urho, Niina, Pessia, Alberto, Hakkarainen, Antti, Kuula, Juho, Heinonen, Ulla, Schmidt, Mark S., Haimilahti, Kimmo, Piirilä, Päivi, Lundbom, Nina, Taskinen, Marja-Riitta, Brenner, Charles, Velagapudi, Vidya, Pietiläinen, Kirsi H., Suomalainen, Anu

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Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD+ Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures von Elhassan, Yasir S., Kluckova, Katarina, Fletcher, Rachel S., Schmidt, Mark S., Garten, Antje, Doig, Craig L., Cartwright, David M., Oakey, Lucy, Burley, Claire V., Jenkinson, Ned, Wilson, Martin, Lucas, Samuel J.E., Akerman, Ildem, Seabright, Alex, Lai, Yu-Chiang, Tennant, Daniel A., Nightingale, Peter, Wallis, Gareth A., Manolopoulos, Konstantinos N., Brenner, Charles, Philp, Andrew, Lavery, Gareth G.

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Pharmacological bypass of NAD⁺ salvage pathway protects neurons from chemotherapy-induced degeneration von Liu, Hui-wen, Smith, Chadwick B., Schmidt, Mark S., Cambronne, Xiaolu A., Cohen, Michael S., Migaud, Marie E., Brenner, Charles, Goodman, Richard H.

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Efficacy, Safety, and Pharmacokinetics of Coadministered Diethylcarbamazine, Albendazole, and Ivermectin for Treatment of Bancroftian Filariasis von Thomsen, Edward K., Sanuku, Nelly, Baea, Manasseh, Satofan, Samson, Maki, Elit, Lombore, Bart, Schmidt, Mark S., Siba, Peter M., Weil, Gary J., Kazura, James W., Fleckenstein, Lawrence L., King, Christopher L.

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Nicotinamide riboside, a form of vitamin B3, protects against excitotoxicity‐induced axonal degeneration von Vaur, Pauline, Brugg, Bernard, Mericskay, Mathias, Li, Zhenlin, Schmidt, Mark S., Vivien, Denis, Orset, Cyrille, Jacotot, Etienne, Brenner, Charles, Duplus, Eric

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Nicotinamide riboside, a form of vitamin B3 and NAD+ precursor, relieves the nociceptive and aversive dimensions of paclitaxel-induced peripheral neuropathy in female rats von Hamity, Marta V., White, Stephanie R., Walder, Roxanne Y., Schmidt, Mark S., Brenner, Charles, Hammond, Donna L.

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Boosting NAD+ blunts TLR4-induced type I IFN in control and systemic lupus erythematosus monocytes von Wu, Jing, Singh, Komudi, Lin, Amy, Meadows, Allison M, Wu, Kaiyuan, Shing, Vivian, Bley, Maximilian, Hassanzadeh, Shahin, Huffstutler, Rebecca D, Schmidt, Mark S, Blanco, Luz P, Tian, Rong, Brenner, Charles, Pirooznia, Mehdi, Kaplan, Mariana J, Sack, Michael N

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PPM1D mutations silence NAPRT gene expression and confer NAMPT inhibitor sensitivity in glioma von Fons, Nathan R., Sundaram, Ranjini K., Breuer, Gregory A., Peng, Sen, McLean, Ryan L., Kalathil, Aravind N., Schmidt, Mark S., Carvalho, Diana M., Mackay, Alan, Jones, Chris, Carcaboso, Ángel M., Nazarian, Javad, Berens, Michael E., Brenner, Charles, Bindra, Ranjit S.

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Niacin Cures Systemic NAD+ Deficiency and Improves Muscle Performance in Adult-Onset Mitochondrial Myopathy von Pirinen, Eija, Auranen, Mari, Khan, Nahid A., Brilhante, Virginia, Urho, Niina, Pessia, Alberto, Hakkarainen, Antti, Ulla Heinonen, Juho Kuula, Schmidt, Mark S., Haimilahti, Kimmo, Piirilä, Päivi, Lundbom, Nina, Taskinen, Marja-Riitta, Brenner, Charles, Velagapudi, Vidya, Pietiläinen, Kirsi H., Suomalainen, Anu

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Nicotinamide Adenine Dinucleotide Metabolome Is Functionally Depressed in Patients Undergoing Liver Transplantation for Alcohol‐Related Liver Disease von Parker, Richard, Schmidt, Mark S., Cain, Owen, Gunson, Bridget, Brenner, Charles

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Nicotinamide riboside improves muscle mitochondrial biogenesis, satellite cell differentiation, and gut microbiota in a twin study von Lapatto, Helena A K, Kuusela, Minna, Heikkinen, Aino, Muniandy, Maheswary, van der Kolk, Birgitta W, Gopalakrishnan, Swetha, Pöllänen, Noora, Sandvik, Martin, Schmidt, Mark S, Heinonen, Sini, Saari, Sina, Kuula, Juho, Hakkarainen, Antti, Tampio, Janne, Saarinen, Tuure, Taskinen, Marja-Riitta, Lundbom, Nina, Groop, Per-Henrik, Tiirola, Marja, Katajisto, Pekka, Lehtonen, Marko, Brenner, Charles, Kaprio, Jaakko, Pekkala, Satu, Ollikainen, Miina, Pietiläinen, Kirsi H, Pirinen, Eija

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Nicotinamide riboside first alleviates symptoms but later downregulates dopamine metabolism in proteasome inhibition mouse model of Parkinson's disease von Turconi, Giorgio, Alam, Farhan, SenGupta, Tanima, Pirnes-Karhu, Sini, Olfat, Soophie, Schmidt, Mark S., Mätlik, Kärt, Montaño-Rodriguez, Ana, Heiskanen, Vladimir, Garton, Daniel, Piepponen, Petteri T., Brenner, Charles, Holmberg, Carina I., Nilsen, Hilde, Pirinen, Eija, Andressoo, Jaan-Olle

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Nicotinamide riboside, a form of vitamin B 3 , protects against excitotoxicity-induced axonal degeneration von Vaur, Pauline, Brugg, Bernard, Mericskay, Mathias, Li, Zhenlin, Schmidt, Mark S, Vivien, Denis, Orset, Cyrille, Jacotot, Etienne, Brenner, Charles, Duplus, Eric

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Absence of evidence that Slc12a8 encodes a nicotinamide mononucleotide transporter von Schmidt, Mark S., Brenner, Charles

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Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice von Mitchell, Sarah J., Bernier, Michel, Aon, Miguel A., Cortassa, Sonia, Kim, Eun Young, Fang, Evandro F., Palacios, Hector H., Ali, Ahmed, Navas-Enamorado, Ignacio, Di Francesco, Andrea, Kaiser, Tamzin A., Waltz, Tyler B., Zhang, Ning, Ellis, James L., Elliott, Peter J., Frederick, David W., Bohr, Vilhelm A., Schmidt, Mark S., Brenner, Charles, Sinclair, David A., Sauve, Anthony A., Baur, Joseph A., de Cabo, Rafael

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