Discovery of novel AKT inhibitors with enhanced anti-tumor effects in combination with the MEK inhibitor von Dumble, Melissa, Crouthamel, Ming-Chih, Zhang, Shu-Yun, Schaber, Michael, Levy, Dana, Robell, Kimberly, Liu, Qi, Figueroa, David J, Minthorn, Elisabeth A, Seefeld, Mark A, Rouse, Meagan B, Rabindran, Sridhar K, Heerding, Dirk A, Kumar, Rakesh

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Allosteric Wip1 phosphatase inhibition through flap-subdomain interaction von Gilmartin, Aidan G, Faitg, Thomas H, Richter, Mark, Groy, Arthur, Seefeld, Mark A, Darcy, Michael G, Peng, Xin, Federowicz, Kelly, Yang, Jingsong, Zhang, Shu-Yun, Minthorn, Elisabeth, Jaworski, Jon-Paul, Schaber, Michael, Martens, Stan, McNulty, Dean E, Sinnamon, Robert H, Zhang, Hong, Kirkpatrick, Robert B, Nevins, Neysa, Cui, Guanglei, Pietrak, Beth, Diaz, Elsie, Jones, Amber, Brandt, Martin, Schwartz, Benjamin, Heerding, Dirk A, Kumar, Rakesh

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Indole Naphthyridinones as Inhibitors of Bacterial Enoyl-ACP Reductases FabI and FabK von Seefeld, Mark A, Miller, William H, Newlander, Kenneth A, Burgess, Walter J, DeWolf, Walter E, Elkins, Patricia A, Head, Martha S, Jakas, Dalia R, Janson, Cheryl A, Keller, Paul M, Manley, Peter J, Moore, Terrance D, Payne, David J, Pearson, Stewart, Polizzi, Brian J, Qiu, Xiayang, Rittenhouse, Stephen F, Uzinskas, Irene N, Wallis, Nicola G, Huffman, William F

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Discovery of Aminopyridine-Based Inhibitors of Bacterial Enoyl-ACP Reductase (FabI) von Miller, William H, Seefeld, Mark A, Newlander, Kenneth A, Uzinskas, Irene N, Burgess, Walter J, Heerding, Dirk A, Yuan, Catherine C. K, Head, Martha S, Payne, David J, Rittenhouse, Stephen F, Moore, Terrance D, Pearson, Stewart C, Berry, Valerie, DeWolf, Walter E, Keller, Paul M, Polizzi, Brian J, Qiu, Xiayang, Janson, Cheryl A, Huffman, William F

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Inhibitors of Pantothenate Kinase: Novel Antibiotics for Staphylococcal Infections von CHOUDHRY, Anthony E, MANDICHAK, Tracy L, RATNAM, Kapila, BROSKEY, John P, EGOLF, Richard W, KINSLAND, Cynthia, BEGLEY, Tadhg P, SEEFELD, Mark A, KU, Thomas W, BROWN, James R, ZALACAIN, Magdalena

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Defining and Combating the Mechanisms of Triclosan Resistance in Clinical Isolates of Staphylococcus aureus von FAN, Frank, KANG YAN, SEEFELD, Mark A, NEWLANDER, Kenneth A, JAKAS, Dalia R, HEAD, Martha S, PAYNE, David J, WALLIS, Nicola G, REED, Shannon, MOORE, Terrance D, RITTENHOUSE, Stephen F, DEWOLF, Walter E, JIANZHONG HUANG, MCDEVITT, Damien, MILLER, William H

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Novel KV7 ion channel openers for the treatment of epilepsy and implications for detrusor tissue contraction von Seefeld, Mark A., Lin, Hong, Holenz, Joerg, Downie, Dave, Donovan, Brian, Fu, Tingting, Pasikanti, Kishore, Zhen, Wei, Cato, Matthew, Chaudhary, Khuram W., Brady, Pat, Bakshi, Tania, Morrow, Dwight, Rajagopal, Sridharan, Samanta, Swapan Kumar, Madhyastha, Naveena, Kuppusamy, Bharathi Mohan, Dougherty, Robert W., Bhamidipati, Ravi, Mohd, Zainuddin, Higgins, Guy A., Chapman, Mark, Rouget, Céline, Lluel, Philippe, Matsuoka, Yasuji

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Unusual ligand-dependent chemoselective Suzuki–Miyaura cross-coupling reactions of 3-bromo-4-trifloyl-thiophenes von Wang, Jizhou, Seefeld, Mark A., Luengo, Juan

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Inhibitors of bacterial enoyl acyl carrier protein reductase (FabI): 2,9-disubstituted 1,2,3,4-tetrahydropyrido[3,4- b]indoles as potential antibacterial agents von Seefeld, Mark A, Miller, William H, Newlander, Kenneth A, Burgess, Walter J, Payne, David J, Rittenhouse, Stephen F, Moore, Terrance D, DeWolf, Walter E, Keller, Paul M, Qiu, Xiayang, Janson, Cheryl A, Vaidya, Kalindi, Fosberry, Andrew P, Smyth, Martin G, Jaworski, Deborah D, Slater-Radosti, Courtney, Huffman, William F

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Aminofurazans as potent inhibitors of AKT kinase von Rouse, Meagan B., Seefeld, Mark A., Leber, Jack D., McNulty, Kenneth C., Sun, Lihui, Miller, William H., Zhang, ShuYun, Minthorn, Elisabeth A., Concha, Nestor O., Choudhry, Anthony E., Schaber, Michael D., Heerding, Dirk A.

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Discovery of 5-pyrrolopyridinyl-2-thiophenecarboxamides as potent AKT kinase inhibitors von Seefeld, Mark A., Rouse, Meagan B., McNulty, Kenneth C., Sun, Lihui, Wang, Jizhou, Yamashita, Dennis S., Luengo, Juan I., Zhang, ShuYun, Minthorn, Elisabeth A., Concha, Nestor O., Heerding, Dirk A.

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Stereoselective Alkylations in Rigid Systems. Effect of Remote Substituents on π-Facial Additions to Lactam Enolates. Stereoelectronic and Steric Effects von Meyers, A. I, Seefeld, Mark A, Lefker, Bruce A, Blake, James F, Williard, Paul G

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Convenient Asymmetric Syntheses of anti-β-Amino Alcohols von Barrett, Anthony G. M, Seefeld, Mark A, White, Andrew J. P, Williams, David J

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Origin of Stereochemistry in Simple Pyrrolidinone Enolate Alkylations von Meyers, A. I, Seefeld, Mark A, Lefker, Bruce A, Blake, James F

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ChemInform Abstract: Unusual Ligand-Dependent Chemoselective Suzuki-Miyaura Cross-Coupling Reactions of 3-Bromo-4-trifloyl-thiophenes von Wang, Jizhou, Seefeld, Mark A., Luengo, Juan

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Novel K V 7 ion channel openers for the treatment of epilepsy and implications for detrusor tissue contraction von Seefeld, Mark A, Lin, Hong, Holenz, Joerg, Downie, Dave, Donovan, Brian, Fu, Tingting, Pasikanti, Kishore, Zhen, Wei, Cato, Matthew, Chaudhary, Khuram W, Brady, Pat, Bakshi, Tania, Morrow, Dwight, Rajagopal, Sridharan, Samanta, Swapan Kumar, Madhyastha, Naveena, Kuppusamy, Bharathi Mohan, Dougherty, Robert W, Bhamidipati, Ravi, Mohd, Zainuddin, Higgins, Guy A, Chapman, Mark, Rouget, Céline, Lluel, Philippe, Matsuoka, Yasuji

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Discovery of a Novel and Potent Class of FabI-Directed Antibacterial Agents von PAYNE, David J, MILLER, William H, HEERDING, Dirk A, JANSON, Cheryl A, JAWORSKI, Deborah D, KELLER, Paul M, MANLEY, Peter J, MOORE, Terrance D, NEWLANDER, Kenneth A, PEARSON, Stewart, POLIZZI, Brian J, XIAYANG QIU, BERRY, Valerie, RITTENHOUSE, Stephen F, SLATER-RADOSTI, Courtney, SALYERS, Kevin L, SEEFELD, Mark A, SMYTH, Martin G, TAKATA, Dennis T, UZINSKAS, Irene N, VAIDYA, Kalindi, WALLIS, Nicola G, WINRAM, Scott B, BROSKY, John, YUAN, Catherine C. K, HUFFMAN, William F, BURGESS, Walter J, CHEN, Emile, DEWOLF, Walter E, FOSBERRY, Andrew P, GREENWOOD, Rebecca, HEAD, Martha S

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Abstract C74: Reassessing IKKε as a novel oncology target von Richter, Mark C., Groy, Arthur X., Wang, Da-Yuan, Lu, Quinn, Holbrook, Joanna D., Sarpong, Martha A., Seefeld, Mark A., Smith, Danielle M., Laquerre, Sylvie G., Gilmartin, Aidan G.

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The use of B-[( E)-3-(diphenylamino)allyl]diisopinocampheylborane as a reagent for the stereoselective synthesis of anti-β-diphenylamino alcohols and trans-1-diphenylamino-2-(1-hyd... von Barrett, Anthony G.M., Seefeld, Mark A.

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B-[(E)-3-(diphenylamino)ally]diisopinocampheylborane : an excellent reagent for the stereoselective synthesis of anti-β-diphenylamino alcohols von BARRETT, A. G. M, SEEFELD, M. A

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