Clinical efficacy and biomarker analysis of neoadjuvant atezolizumab in operable urothelial carcinoma in the ABACUS trial von Powles, Thomas, Kockx, Mark, Rodriguez-Vida, Alejo, Duran, Ignacio, Crabb, Simon J., Van Der Heijden, Michiel S., Szabados, Bernadett, Pous, Albert Font, Gravis, Gwenaelle, Herranz, Urbano Anido, Protheroe, Andrew, Ravaud, Alain, Maillet, Denis, Mendez, Maria Jose, Suarez, Cristina, Linch, Mark, Prendergast, Aaron, van Dam, Pieter-Jan, Stanoeva, Diana, Daelemans, Sofie, Mariathasan, Sanjeev, Tea, Joy S., Mousa, Kelly, Banchereau, Romain, Castellano, Daniel

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Antibody–Antibiotic Conjugates: A Novel Therapeutic Platform against Bacterial Infections von Mariathasan, Sanjeev, Tan, Man-Wah

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Molecular determinants of response to PD-L1 blockade across tumor types von Banchereau, Romain, Leng, Ning, Zill, Oliver, Sokol, Ethan, Liu, Gengbo, Pavlick, Dean, Maund, Sophia, Liu, Li-Fen, Kadel, Edward, Baldwin, Nicole, Jhunjhunwala, Suchit, Nickles, Dorothee, Assaf, Zoe June, Bower, Daniel, Patil, Namrata, McCleland, Mark, Shames, David, Molinero, Luciana, Huseni, Mahrukh, Sanjabi, Shomyseh, Cummings, Craig, Mellman, Ira, Mariathasan, Sanjeev, Hegde, Priti, Powles, Thomas

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Molecular Subsets in Renal Cancer Determine Outcome to Checkpoint and Angiogenesis Blockade von Motzer, Robert J., Banchereau, Romain, Hamidi, Habib, Powles, Thomas, McDermott, David, Atkins, Michael B., Escudier, Bernard, Liu, Li-Fen, Leng, Ning, Abbas, Alexander R., Fan, Jinzhen, Koeppen, Hartmut, Lin, Jennifer, Carroll, Susheela, Hashimoto, Kenji, Mariathasan, Sanjeev, Green, Marjorie, Tayama, Darren, Hegde, Priti S., Schiff, Christina, Huseni, Mahrukh A., Rini, Brian

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High systemic and tumor-associated IL-8 correlates with reduced clinical benefit of PD-L1 blockade von Yuen, Kobe C., Liu, Li-Fen, Gupta, Vinita, Madireddi, Shravan, Keerthivasan, Shilpa, Li, Congfen, Rishipathak, Deepali, Williams, Patrick, Kadel, Edward E., Koeppen, Hartmut, Chen, Ying-Jiun, Modrusan, Zora, Grogan, Jane L., Banchereau, Romain, Leng, Ning, Thastrom, AnnChristine, Shen, Xiadong, Hashimoto, Kenji, Tayama, Darren, van der Heijden, Michiel S., Rosenberg, Jonathan E., McDermott, David F., Powles, Thomas, Hegde, Priti S., Huseni, Mahrukh A., Mariathasan, Sanjeev

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ASC, Ipaf and Cryopyrin/Nalp3: bona fide intracellular adapters of the caspase-1 inflammasome von Mariathasan, Sanjeev

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Atezolizumab with enzalutamide versus enzalutamide alone in metastatic castration-resistant prostate cancer: a randomized phase 3 trial von Powles, Thomas, Yuen, Kobe C., Gillessen, Silke, Kadel, Edward E., Rathkopf, Dana, Matsubara, Nobuaki, Drake, Charles G., Fizazi, Karim, Piulats, Josep M., Wysocki, Piotr J., Buchschacher, Gary L., Alekseev, Boris, Mellado, Begoña, Karaszewska, Bogusława, Doss, Jennifer F., Rasuo, Grozdana, Datye, Asim, Mariathasan, Sanjeev, Williams, Patrick, Sweeney, Christopher J.

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Germline genetic polymorphisms influence tumor gene expression and immune cell infiltration von Lim, Yoong Wearn, Chen-Harris, Haiyin, Mayba, Oleg, Lianoglou, Steve, Wuster, Arthur, Bhangale, Tushar, Khan, Zia, Mariathasan, Sanjeev, Daemen, Anneleen, Reeder, Jens, Haverty, Peter M., Forrest, William F., Brauer, Matthew, Mellman, Ira, Albert, Matthew L.

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Polygenic risk for skin autoimmunity impacts immune checkpoint blockade in bladder cancer von Khan, Zia, Di Nucci, Flavia, Kwan, Antonia, Hammer, Christian, Mariathasan, Sanjeev, Rouilly, Vincent, Carroll, Jonathan, Fontes, Magnus, Acosta, Sergio Ley, Guardino, Ellie, Chen-Harris, Haiyin, Bhangale, Tushar, Mellman, Ira, Rosenberg, Jonathan, Powles, Thomas, Hunkapiller, Julie, Chandler, G. Scott, Albert, Matthew L.

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Cryopyrin activates the inflammasome in response to toxins and ATP von Roose-Girma, Meron, Lee, Wyne P, Mariathasan, Sanjeev, Weinrauch, Yvette, Newton, Kim, Monack, Denise M, Dixit, Vishva M, O'Rourke, Karen, Weiss, David S, McBride, Jacqueline

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Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody–drug conjugates von Staben, Leanna R., Koenig, Stefan G., Lehar, Sophie M., Vandlen, Richard, Zhang, Donglu, Chuh, Josefa, Yu, Shang-Fan, Ng, Carl, Guo, Jun, Liu, Yanzhou, Fourie-O'Donohue, Aimee, Go, MaryAnn, Linghu, Xin, Segraves, Nathaniel L., Wang, Tao, Chen, Jinhua, Wei, BinQing, Phillips, Gail D. Lewis, Xu, Keyang, Kozak, Katherine R., Mariathasan, Sanjeev, Flygare, John A., Pillow, Thomas H.

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Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf von Dixit, Vishva M, Mariathasan, Sanjeev, Newton, Kim, Monack, Denise M, Vucic, Domagoj, French, Dorothy M, Lee, Wyne P, Roose-Girma, Meron, Erickson, Sharon

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NOD2-NALP1 complex mediates caspase-1-dependent IL-1β secretion in response to Bacillus anthracis infection and muramyl dipeptide von Hsu, Li-Chung, Ali, Syed R, McGillivray, Shauna, Tseng, Ping-Hui, Mariathasan, Sanjeev, Humke, Eric W, Eckmann, Lars, Powell, Jonathan J, Nizet, Victor, Dixit, Vishva M, Karin, Michael

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Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis von Mariathasan, Sanjeev, Weiss, David S, Dixit, Vishva M, Monack, Denise M

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Analytical validation of a novel comprehensive genomic profiling informed circulating tumor DNA monitoring assay for solid tumors von Zollinger, Daniel R, Rivers, Elizabeth, Fine, Alexander, Huang, Yanmei, Son, Joseph, Kalyan, Akshita, Gray, Wren, Baharian, Golshid, Hammond, Carly, Ram, Rosalyn, Ringman, Lindsay, Hafez, Dina, Savel, Daniel, Patel, Vipul, Dantone, Marc, Guo, Cui, Childress, Merrida, Xu, Chang, Johng, Dorhyun, Wallden, Brett, Pokharel, Prapti, Camara, William, Hegde, Priti S, Hughes, Jason, Carter, Corey, Davarpanah, Nicole, Degaonkar, Viraj, Gupta, Pratyush, Mariathasan, Sanjeev, Powles, Thomas, Ferree, Sean, Dennis, Lucas, Young, Amanda

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Intratumoral CD103+ CD8+ T cells predict response to PD-L1 blockade von Banchereau, Romain, Chitre, Avantika S., Scherl, Alexis, Wu, Thomas D., Patil, Namrata S., de Almeida, Patricia, Kadel, III, Edward E., Madireddi, Shravan, Au-Yeung, Amelia, Takahashi, Chikara, Chen, Ying-Jiun, Modrusan, Zora, McBride, Jacqueline, Nersesian, Rhea, El-Gabry, Ehab A., Robida, Mark D., Hung, Jeffrey C., Kowanetz, Marcin, Zou, Wei, McCleland, Mark, Caplazi, Patrick, Eshgi, Shadi Toghi, Koeppen, Hartmut, Hegde, Priti S., Mellman, Ira, Mathews, W. Rodney, Powles, Thomas, Mariathasan, Sanjeev, Grogan, Jane, O'Gorman, William E

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The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection von Roy, Craig R, Zamboni, Dario S, Kobayashi, Koichi S, Kohlsdorf, Tiana, Ogura, Yasunori, Long, E Michelle, Vance, Russell E, Kuida, Keisuke, Mariathasan, Sanjeev, Dixit, Vishva M, Flavell, Richard A, Dietrich, William F

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Single-cell analysis reveals clonally expanded tumor-associated CD57+ CD8 T cells are enriched in the periphery of patients with metastatic urothelial cancer responding to PD-L1 bl... von Fehlings, Michael, Kim, Leesun, Guan, Xiangnan, Yuen, Kobe, Tafazzol, Alireza, Sanjabi, Shomyseh, Zill, Oliver A, Rishipathak, Deepali, Wallace, Andrew, Nardin, Alessandra, Ma, Siming, Milojkovic, Ana, Newell, Evan W, Mariathasan, Sanjeev, Yadav, Mahesh

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Molecular residual disease detection in resected, muscle-invasive urothelial cancer with a tissue-based comprehensive genomic profiling–informed personalized monitoring assay von Powles, Thomas, Young, Amanda, Nimeiri, Halla, Madison, Russell W., Fine, Alexander, Zollinger, Daniel R., Huang, Yanmei, Xu, Chang, Gjoerup, Ole V., Aushev, Vasily N., Wu, Hsin-Ta, Aleshin, Alexey, Carter, Corey, Davarpanah, Nicole, Degaonkar, Viraj, Gupta, Pratyush, Mariathasan, Sanjeev, Schleifman, Erica, Assaf, Zoe June, Oxnard, Geoffrey, Hegde, Priti S.

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Author Correction: High systemic and tumor-associated IL-8 correlates with reduced clinical benefit of PD-L1 blockade von Yuen, Kobe C., Liu, Li-Fen, Gupta, Vinita, Madireddi, Shravan, Keerthivasan, Shilpa, Li, Congfen, Rishipathak, Deepali, Williams, Patrick, Kadel, Edward E., Koeppen, Hartmut, Chen, Ying-Jiun, Modrusan, Zora, Grogan, Jane L., Banchereau, Romain, Leng, Ning, Thastrom, AnnChristine, Shen, Xiadong, Hashimoto, Kenji, Tayama, Darren, van der Heijden, Michiel S., Rosenberg, Jonathan E., McDermott, David F., Powles, Thomas, Hegde, Priti S., Huseni, Mahrukh A., Mariathasan, Sanjeev

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