Target Identification in Anti-Tuberculosis Drug Discovery von Capela, Rita, Félix, Rita, Clariano, Marta, Nunes, Diogo, Perry, Maria de Jesus, Lopes, Francisca

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Monocarbonyl Analogs of Curcumin with Potential to Treat Colorectal Cancer von Clariano, Marta, Marques, Vanda, Vaz, João, Awam, Salma, Afonso, Marta B., Jesus Perry, Maria, Rodrigues, Cecília MP

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Clinicogenomic landscape of pancreatic adenocarcinoma identifies KRAS mutant dosage as prognostic of overall survival von Varghese, Anna M, Perry, Maria A, Chou, Joanne F, Nandakumar, Subhiksha, Muldoon, Daniel, Erakky, Amanda, Zucker, Amanda, Fong, Christopher, Mehine, Miika, Nguyen, Bastien, Basturk, Olca, Balogun, Fiyinfolu, Kelsen, David P, Brannon, A Rose, Mandelker, Diana, Vakiani, Efsevia, Park, Wungki, Yu, Kenneth H, Stadler, Zsofia K, Schattner, Mark A, Jarnagin, William R, Wei, Alice C, Chakravarty, Debyani, Capanu, Marinela, Schultz, Nikolaus, Berger, Michael F, Iacobuzio-Donahue, Christine A, Bandlamudi, Chaitanya, O'Reilly, Eileen M

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Pan-cancer analysis of biallelic inactivation in tumor suppressor genes identifies KEAP1 zygosity as a predictive biomarker in lung cancer von Zucker, Mark, Perry, Maria A, Gould, Samuel I, Elkrief, Arielle, Safonov, Anton, Thummalapalli, Rohit, Mehine, Miika, Chakravarty, Debyani, Brannon, A Rose, Ladanyi, Marc, Razavi, Pedram, Donoghue, Mark T A, Murciano-Goroff, Yonina R, Grigoriadis, Kristiana, McGranahan, Nicholas, Jamal-Hanjani, Mariam, Swanton, Charles, Chen, Yuan, Shen, Ronglai, Chandarlapaty, Sarat, Solit, David B, Schultz, Nikolaus, Berger, Michael F, Chang, Jason, Schoenfeld, Adam J, Sánchez-Rivera, Francisco J, Reznik, Ed, Bandlamudi, Chaitanya

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Discovery of a Necroptosis Inhibitor Improving Dopaminergic Neuronal Loss after MPTP Exposure in Mice von Oliveira, Sara R., Dionísio, Pedro A., Gaspar, Maria M., Ferreira, Maria B. T., Rodrigues, Catarina A. B., Pereira, Rita G., Estevão, Mónica S., Perry, Maria J., Moreira, Rui, Afonso, Carlos A. M., Amaral, Joana D., Rodrigues, Cecília M. P.

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From hybrid compounds to targeted drug delivery in antimalarial therapy von Oliveira, Rudi, Miranda, Daniela, Magalhães, Joana, Capela, Rita, Perry, Maria J., O’Neill, Paul M., Moreira, Rui, Lopes, Francisca

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Adjuvant Modified FOLFIRINOX for Resected Pancreatic Adenocarcinoma (PDAC): Clinical Insights and Genomic Features from a Large Contemporary Cohort von Keane, Fergus, O'Connor, Catherine, Moss, Drew, Chou, Joanne F, Perry, Maria A, Crowley, Fionnuala, Saxena, Parima, Chan, Amelia, Schoenfeld, Joshua D, Singhal, Anupriya, Park, Wungki, Cowzer, Darren, Harrold, Emily, Varghese, Anna M, El Dika, Imane, Crane, Christopher, Harding, James J, Abou-Alfa, Ghassan K, Kingham, T Peter, Wei, Alice C, Yu, Kenneth H, D'Angelica, Michael I, Balachandran, Vinod P, Drebin, Jeffrey, Jarnagin, William R, Bandlamudi, Chaitanya, Kelsen, David, Capanu, Marinela, Soares, Kevin C, Balogun, Fiyinfolu, O'Reilly, Eileen M

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Endoperoxide-8-aminoquinoline hybrids as dual-stage antimalarial agents with enhanced metabolic stability von Capela, Rita, Magalhães, Joana, Miranda, Daniela, Machado, Marta, Sanches-Vaz, Margarida, Albuquerque, Inês S., Sharma, Moni, Gut, Jiri, Rosenthal, Philip J., Frade, Raquel, Perry, Maria J., Moreira, Rui, Prudêncio, Miguel, Lopes, Francisca

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Targeting gliomas with triazene-based hybrids: Structure-activity relationship, mechanistic study and stability von Braga, Cláudia, Vaz, Ana R., Oliveira, M. Conceição, Matilde Marques, M., Moreira, Rui, Brites, Dora, Perry, Maria J.

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Nitroaromatic-based triazene prodrugs to target the hypoxic microenvironment in glioblastoma von Braga, Cláudia, Ferreira-Silva, Margarida, Corvo, M Luísa, Moreira, Rui, Fernandes, Alexandra R, Vaz, João, Perry, Maria J

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Synthesis, anticancer activity and UPLC analysis of the stability of some new benzimidazole-4,7-dione derivatives von Błaszczak-Swiatkiewicz, Katarzyna, Almeida, Diogo Correia, De Jesus Perry, Maria, Mikiciuk-Olasik, Elżbieta

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Targeting Gliomas: Can a New Alkylating Hybrid Compound Make a Difference? von Pinheiro, Rui, Braga, Cláudia, Santos, Gisela, Bronze, Maria R, Perry, Maria J, Moreira, Rui, Brites, Dora, Falcão, Ana S

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Not all KRAS-mutated pancreatic cancers are equal - mutant dosage matters

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Targeting the Erythrocytic and Liver Stages of Malaria Parasites with s-Triazine-Based Hybrids von Rodrigues, Catarina A. B., Frade, Raquel F. M., Albuquerque, Inês S., Perry, Maria J., Gut, Jiri, Machado, Marta, Rosenthal, Philip J., Prudêncio, Miguel, Afonso, Carlos A. M., Moreira, Rui

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Necroptosis induced by ruthenium (II) complexes as mitochondrial disruptors von Gonçalves, Joana, Amaral, Joana D., Capela, Rita, Perry, Maria de Jesus, Braga, Cláudia, Gaspar, Maria Manuela, Piedade, Fátima M., Bijlsma, Lubertus, Roig, Antoni, Pinto, Sandra N., Moreira, Rui, Florindo, Pedro, Rodrigues, Cecília M. P.

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Enantiopure Indolizinoindolones with in vitro Activity against Blood- and Liver-Stage Malaria Parasites von Pereira, Nuno A. L., Monteiro, Ângelo, Machado, Marta, Gut, Jiri, Molins, Elies, Perry, M. Jesus, Dourado, Jorge, Moreira, Rui, Rosenthal, Philip J., Prudêncio, Miguel, Santos, Maria M. M.

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Metabolism of N-ethylhexedrone and buphedrone: An in vivo study in mice using HPLC-MS/MS von Carrola, Joana, Duarte, Noélia, Florindo, Pedro, Henriques, Sara, da Silva, Gustavo, Bijlsma, Lubertus, Moreira, Rui, Correia, Catarina, Perry, Maria de Jesus, Lopes, Álvaro, de Mello-Sampayo, Cristina, Bronze, Maria do Rosário

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Clinical outcomes for IDH1 mutant biliary tract cancer (BTC) treated with contemporary systemic therapy von Cowzer, Darren, Huq, Risha, Perry, Maria, Keane, Fergus, Park, Wungki, El Dika, Imane H., Khalil, Danny, Shia, Jinru, Sigel, Carlie S., Bandlamudi, Chaitanya, Berger, Michael F., Solit, David B., O'Reilly, Eileen Mary, Abou-Alfa, Ghassan K., Harding, James J.

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A step forward on the in vitro and in vivo assessment of a novel nanomedicine against melanoma von Pinho, Jacinta O., Matias, Mariana, Godinho-Santos, Ana, Amaral, Joana D., Mendes, Eduarda, Perry, Maria Jesus, Francisco, Ana Paula, Rodrigues, Cecília M.P., Gaspar, M. Manuela

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Sulfur Analogues of Tyrosine in the Development of Triazene Hybrid Compounds: A New Strategy against Melanoma von Granada, Margarida, Mendes, Eduarda, Perry, Maria Jesus, Penetra, Maria João, Gaspar, Maria Manuela, Pinho, Jacinta O, Serra, Sofia, António, Catarina Teixeira, Francisco, Ana Paula

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