Glyceraldehyde-3-phosphate Dehydrogenase is a Multifaceted Therapeutic Target von Lazarev, Vladimir F, Guzhova, Irina V, Margulis, Boris A

Volltext

Hsp70 Negatively Regulates Autophagy via Governing AMPK Activation, and Dual Hsp70-Autophagy Inhibition Induces Synergetic Cell Death in NSCLC Cells von Alhasan, Bashar, Gladova, Yana A, Sverchinsky, Dmitry V, Aksenov, Nikolai D, Margulis, Boris A, Guzhova, Irina V

Volltext

Hsp70-containing extracellular vesicles are capable of activating of adaptive immunity in models of mouse melanoma and colon carcinoma von Komarova, Elena Y., Suezov, Roman V., Nikotina, Alina D., Aksenov, Nikolay D., Garaeva, Luiza A., Shtam, Tatiana A., Zhakhov, Alexander V., Martynova, Marina G., Bystrova, Olga A., Istomina, Maria S., Ischenko, Alexander M., Margulis, Boris A., Guzhova, Irina V.

Volltext

New HSF1 inducer as a therapeutic agent in a rodent model of Parkinson's disease von Ekimova, Irina V., Plaksina, Daria V., Pastukhov, Yuri F., Lapshina, Ksenia V., Lazarev, Vladimir F., Mikhaylova, Elena R., Polonik, Sergey G., Pani, Bibhusita, Margulis, Boris A., Guzhova, Irina V., Nudler, Evgeny

Volltext

Disruption of the Complex between GAPDH and Hsp70 Sensitizes C6 Glioblastoma Cells to Hypoxic Stress von Mikeladze, Marina A, Dutysheva, Elizaveta A, Kartsev, Victor G, Margulis, Boris A, Guzhova, Irina V, Lazarev, Vladimir F

Volltext

Indolylazine Derivative Induces Chaperone Expression in Aged Neural Cells and Prevents the Progression of Alzheimer's Disease von Lazarev, Vladimir F, Dutysheva, Elizaveta A, Mikhaylova, Elena R, Trestsova, Maria A, Utepova, Irina A, Chupakhin, Oleg N, Margulis, Boris A, Guzhova, Irina V

Volltext

Prevention of High Glucose-Mediated EMT by Inhibition of Hsp70 Chaperone von Nikotina, Alina D., Vladimirova, Snezhana A., Komarova, Elena Y., Alexeev, Dmitry, Efremov, Sergey, Leonova, Elizaveta, Pavlov, Rostislav, Kartsev, Viktor G., Polonik, Sergey G., Margulis, Boris A., Guzhova, Irina V.

Volltext

Hsp70 chaperone rescues C6 rat glioblastoma cells from oxidative stress by sequestration of aggregating GAPDH von Lazarev, Vladimir F., Nikotina, Alina D., Mikhaylova, Elena R., Nudler, Evgeny, Polonik, Sergey G., Guzhova, Irina V., Margulis, Boris A.

Volltext

Protein Interactome of Amyloid-β as a Therapeutic Target von Lazarev, Vladimir F, Dutysheva, Elizaveta A, Kanunikov, Igor E, Guzhova, Irina V, Margulis, Boris A

Volltext

Autocrine regulation of tumor cell repopulation by Hsp70-HMGB1 alarmin complex von Sverchinsky, Dmitry V, Alhasan, Bashar A, Mikeladze, Marina A, Lazarev, Vladimir F, Kuznetcova, Liubov S, Morshneva, Alisa V, Nikotina, Alina D, Ziewanah, Amr, Koludarova, Lidia V, Starkova, Tatiana Y, Margulis, Boris A, Guzhova, Irina V

Volltext

Etoposide-Induced Apoptosis in Cancer Cells Can Be Reinforced by an Uncoupled Link between Hsp70 and Caspase-3 von Sverchinsky, Dmitry V, Nikotina, Alina D, Komarova, Elena Y, Mikhaylova, Elena R, Aksenov, Nikolay D, Lazarev, Vladimir F, Mitkevich, Vladimir A, Suezov, Roman, Druzhilovskiy, Dmitry S, Poroikov, Vladimir V, Margulis, Boris A, Guzhova, Irina V

Volltext

Peptide fragments of Hsp70 modulate its chaperone activity and sensitize tumor cells to anti‐cancer drugs von Sverchinsky, Dmitry V., Lazarev, Vladimir F., Semenyuk, Pavel I., Mitkevich, Vladimir A., Guzhova, Irina V., Margulis, Boris A.

Volltext

The mTOR Pathway in Pluripotent Stem Cells: Lessons for Understanding Cancer Cell Dormancy von Alhasan, Bashar A, Gordeev, Sergei A, Knyazeva, Aleksandra R, Aleksandrova, Kseniia V, Margulis, Boris A, Guzhova, Irina V, Suvorova, Irina I

Volltext

Possible Function of Molecular Chaperones in Diseases Caused by Propagating Amyloid Aggregates von Lazarev, Vladimir F, Mikhaylova, Elena R, Guzhova, Irina V, Margulis, Boris A

Volltext

Detection of experimental myocardium infarction in rats by MRI using heat shock protein 70 conjugated superparamagnetic iron oxide nanoparticle von Shevtsov, Maxim A., MD, PhD, Nikolaev, Boris P., PhD, Ryzhov, Vyacheslav A., PhD, Yakovleva, Ludmila Y., MS, Dobrodumov, Anatolii V., PhD, Marchenko, Yaroslav Y., MS, Margulis, Boris A., PhD, Dr.Sci, Pitkin, Emil, PhD, Mikhrina, Anastasiy L., MS, Guzhova, Irina V., PhD, Dr.Sci, Multhoff, Gabriele, Prof. Dr

Volltext

GAPDH binders as potential drugs for the therapy of polyglutamine diseases: Design of a new screening assay von Lazarev, Vladimir F., Benken, Konstantin A., Semenyuk, Pavel I., Sarantseva, Svetlana V., Bolshakova, Olga I., Mikhaylova, Elena R., Muronetz, Vladimir I., Guzhova, Irina V., Margulis, Boris A.

Volltext

Combined Cytotoxic Effect of Inhibitors of Proteostasis on Human Colon Cancer Cells von Nikotina, Alina D, Vladimirova, Snezhana A, Kokoreva, Nadezhda E, Komarova, Elena Y, Aksenov, Nikolay D, Efremov, Sergey, Leonova, Elizaveta, Pavlov, Rostislav, Kartsev, Viktor G, Zhang, Zhichao, Margulis, Boris A, Guzhova, Irina V

Volltext

Discovery and optimization of cardenolides inhibiting HSF1 activation in human colon HCT-116 cancer cells von Nikotina, Alina D, Koludarova, Lidia, Komarova, Elena Y, Mikhaylova, Elena R, Aksenov, Nikolay D, Suezov, Roman, Kartzev, Viktor G, Margulis, Boris A, Guzhova, Irina V

Volltext

Combination of a Chaperone Synthesis Inducer and an Inhibitor of GAPDH Aggregation for Rehabilitation after Traumatic Brain Injury: A Pilot Study von Dutysheva, Elizaveta A, Mikhaylova, Elena R, Trestsova, Maria A, Andreev, Alexander I, Apushkin, Danila Yu, Utepova, Irina A, Serebrennikova, Polina O, Akhremenko, Eugenia A, Aksenov, Nikolay D, Bon', Elizaveta I, Zimatkin, Sergey M, Chupakhin, Oleg N, Margulis, Boris A, Guzhova, Irina V, Lazarev, Vladimir F

Volltext

Knock-down of Hdj2/DNAJA1 co-chaperone results in an unexpected burst of tumorigenicity of C6 glioblastoma cells von Meshalkina, Darya A, Shevtsov, Maxim A, Dobrodumov, Anatoliy V, Komarova, Elena Y, Voronkina, Irina V, Lazarev, Vladimir F, Margulis, Boris A, Guzhova, Irina V

Volltext