Functional Genomic Landscape of Human Breast Cancer Drivers, Vulnerabilities, and Resistance von Marcotte, Richard, Sayad, Azin, Brown, Kevin R., Sanchez-Garcia, Felix, Reimand, Jüri, Haider, Maliha, Virtanen, Carl, Bradner, James E., Bader, Gary D., Mills, Gordon B., Pe’er, Dana, Moffat, Jason, Neel, Benjamin G.

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Genome-wide CRISPR screens identify ferroptosis as a novel therapeutic vulnerability in acute lymphoblastic leukemia von Lalonde, Marie-Eve, Sasseville, Marc, Gélinas, Anne-Marie, Milanese, Jean-Sébastien, Béland, Kathie, Drouin, Simon, Haddad, Elie, Marcotte, Richard

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Essential gene profiles in breast, pancreatic, and ovarian cancer cells von Marcotte, Richard, Brown, Kevin R, Suarez, Fernando, Sayad, Azin, Karamboulas, Konstantina, Krzyzanowski, Paul M, Sircoulomb, Fabrice, Medrano, Mauricio, Fedyshyn, Yaroslav, Koh, Judice L Y, van Dyk, Dewald, Fedyshyn, Bodhana, Luhova, Marianna, Brito, Glauber C, Vizeacoumar, Franco J, Vizeacoumar, Frederick S, Datti, Alessandro, Kasimer, Dahlia, Buzina, Alla, Mero, Patricia, Misquitta, Christine, Normand, Josee, Haider, Maliha, Ketela, Troy, Wrana, Jeffrey L, Rottapel, Robert, Neel, Benjamin G, Moffat, Jason

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Akt1 and Akt2 Play Distinct Roles in the Initiation and Metastatic Phases of Mammary Tumor Progression von DILLON, Rachelle L, MARCOTTE, Richard, HENNESSY, Bryan T, WOODGETT, James R, MILLS, Gordon B, MULLER, William J

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The RhoGEF GEF-H1 Is Required for Oncogenic RAS Signaling via KSR-1 von Cullis, Jane, Meiri, David, Sandi, Maria Jose, Radulovich, Nikolina, Kent, Oliver A., Medrano, Mauricio, Mokady, Daphna, Normand, Josee, Larose, Jose, Marcotte, Richard, Marshall, Christopher B., Ikura, Mitsuhiko, Ketela, Troy, Moffat, Jason, Neel, Benjamin G., Gingras, Anne-Claude, Tsao, Ming-Sound, Rottapel, Robert

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CUX2 Protein Functions as an Accessory Factor in the Repair of Oxidative DNA Damage von Pal, Ranjana, Ramdzan, Zubaidah M., Kaur, Simran, Duquette, Philippe M., Marcotte, Richard, Leduy, Lam, Davoudi, Sayeh, Lamarche-Vane, Nathalie, Iulianella, Angelo, Nepveu, Alain

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Mammary epithelial-specific disruption of c-Src impairs cell cycle progression and tumorigenesis von Marcotte, Richard, Smith, Harvey W, Sanguin-Gendreau, Virginie, McDonough, Rosalie V, Muller, William J

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c-Src Associates with ErbB2 through an Interaction between Catalytic Domains and Confers Enhanced Transforming Potential von Marcotte, Richard, Zhou, Lixin, Kim, Harold, Roskelly, Calvin D., Muller, William J.

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Peptide Elongation Factor eEF1A-2/S1 Expression in Cultured Differentiated Myotubes and Its Protective Effect against Caspase- 3-mediated Apoptosis von Ruest, Louis-Bruno, Marcotte, Richard, Wang, Eugenia

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CRISPR Screens Identify Key Regulators of NK Cell Cytotoxicity in Cancer Therapy von Rethacker, Louise, Romero, Hugo, Dulong, Joshua, Sasseville, Marc, Lalonde, Marie-Eve, Gadoury, Christine, Beland, Kathie, Beausejour, Christian, Marcotte, Richard, Haddad, Elie

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PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival during hypoxia von Banh, Robert S., Iorio, Caterina, Marcotte, Richard, Xu, Yang, Cojocari, Dan, Rahman, Anas Abdel, Pawling, Judy, Zhang, Wei, Sinha, Ankit, Rose, Christopher M., Isasa, Marta, Zhang, Shuang, Wu, Ronald, Virtanen, Carl, Hitomi, Toshiaki, Habu, Toshiyuki, Sidhu, Sachdev S., Koizumi, Akio, Wilkins, Sarah E., Kislinger, Thomas, Gygi, Steven P., Schofield, Christopher J., Dennis, James W., Wouters, Bradly G., Neel, Benjamin G.

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Signaling pathway for apoptosis: A racetrack for life or death von Wang, Eugenia, Marcotte, Richard, Petroulakis, Emmanuel

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Migration rather than proliferation transcriptomic signatures are strongly associated with breast cancer patient survival von Nair, Nishanth Ulhas, Das, Avinash, Rogkoti, Vasiliki-Maria, Fokkelman, Michiel, Marcotte, Richard, de Jong, Chiaro G., Koedoot, Esmee, Lee, Joo Sang, Meilijson, Isaac, Hannenhalli, Sridhar, Neel, Benjamin G., de Water, Bob van, Le Dévédec, Sylvia E., Ruppin, Eytan

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Microarray Analysis of E-Box Binding-Related Gene Expression in Young and Replicatively Senescent Human Fibroblasts von Semov, Alexandre, Marcotte, Richard, Semova, Natalie, Ye, Xiangyun, Wang, Eugenia

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Abstract PR14: Integrative functional genomics of breast cancer von Marcotte, Richard, Sayad, Azin, Iorio, Cathy, Moffat, Jason, Neel, Benjamin G.

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Abstract A2-07: Integrative functional genomics of breast cancer von Marcotte, Richard, Sayad, Azin, Iorio, Cathy, Moffat, Jason, Neel, Benjamin G.

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Senescent fibroblasts resist apoptosis by downregulating caspase-3 von Marcotte, Richard, Lacelle, Chantale, Wang, Eugenia

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Signal Transduction in Transgenic Mouse Models of Human Breast Cancer--Implications for Human Breast Cancer von Marcotte, Richard, Muller, William J

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Germline variants associated with leukocyte genes predict tumor recurrence in breast cancer patients von Milanese, Jean-Sébastien, Tibiche, Chabane, Zou, Jinfeng, Meng, Zhigang, Nantel, Andre, Drouin, Simon, Marcotte, Richard, Wang, Edwin

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Abstract PR02: The spliceosome is a therapeutic vulnerability in MYC-driven breast cancer von Hsu, Tiffany, Simon, Lukas, Neill, Nicholas, marcotte, richard, Sayad, Azin, Karlin, Kristen, Lagisetti, Chandraiah, Cooper, Thomas, Webb, Thomas, Neel, Benjamin, Shaw, Chad, Westbrook, Thomas (“Trey”)

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