Encapsulated islets for diabetes therapy: History, current progress, and critical issues requiring solution von Scharp, David W., Marchetti, Piero

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Organ donor pancreases for the study of human islet cell histology and pathophysiology: a precious and valuable resource von Marchetti, Piero, Suleiman, Mara, Marselli, Lorella

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A circular RNA generated from an intron of the insulin gene controls insulin secretion von Stoll, Lisa, Rodríguez-Trejo, Adriana, Guay, Claudiane, Brozzi, Flora, Bayazit, Mustafa Bilal, Gattesco, Sonia, Menoud, Véronique, Sobel, Jonathan, Marques, Ana Claudia, Venø, Morten Trillingsgaard, Esguerra, Jonathan Lou S., Barghouth, Mohammad, Suleiman, Mara, Marselli, Lorella, Kjems, Jørgen, Eliasson, Lena, Renström, Erik, Bouzakri, Karim, Pinget, Michel, Marchetti, Piero, Regazzi, Romano

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Phosphoproteomics Reveals the GSK3-PDX1 Axis as a Key Pathogenic Signaling Node in Diabetic Islets von Sacco, Francesca, Seelig, Anett, Humphrey, Sean J., Krahmer, Natalie, Volta, Francesco, Reggio, Alessio, Marchetti, Piero, Gerdes, Jantje, Mann, Matthias

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Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose von Johnston, Natalie R., Mitchell, Ryan K., Haythorne, Elizabeth, Pessoa, Maria Paiva, Semplici, Francesca, Ferrer, Jorge, Piemonti, Lorenzo, Marchetti, Piero, Bugliani, Marco, Bosco, Domenico, Berishvili, Ekaterine, Duncanson, Philip, Watkinson, Michael, Broichhagen, Johannes, Trauner, Dirk, Rutter, Guy A., Hodson, David J.

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Insulin Autoimmune Syndrome (Hirata Disease): A Comprehensive Review Fifty Years After Its First Description von Cappellani, Daniele, Macchia, Enrico, Falorni, Alberto, Marchetti, Piero

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SARS-CoV-2 Receptor Angiotensin I-Converting Enzyme Type 2 (ACE2) Is Expressed in Human Pancreatic β -Cells and in the Human Pancreas Microvasculature von Fignani, Daniela, Licata, Giada, Brusco, Noemi, Nigi, Laura, Grieco, Giuseppina E, Marselli, Lorella, Overbergh, Lut, Gysemans, Conny, Colli, Maikel L, Marchetti, Piero, Mathieu, Chantal, Eizirik, Decio L, Sebastiani, Guido, Dotta, Francesco

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Optical Nanoscopy of Cytokine-Induced Structural Alterations of the Endoplasmic Reticulum and Golgi Apparatus in Insulin-Secreting Cells von Pugliese, Licia Anna, De Lorenzi, Valentina, Tesi, Marta, Marchetti, Piero, Cardarelli, Francesco

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Targeting GLP-1 receptor trafficking to improve agonist efficacy von Jones, Ben, Buenaventura, Teresa, Kanda, Nisha, Chabosseau, Pauline, Owen, Bryn M., Scott, Rebecca, Goldin, Robert, Angkathunyakul, Napat, Corrêa Jr, Ivan R., Bosco, Domenico, Johnson, Paul R., Piemonti, Lorenzo, Marchetti, Piero, Shapiro, A. M. James, Cochran, Blake J., Hanyaloglu, Aylin C., Inoue, Asuka, Tan, Tricia, Rutter, Guy A., Tomas, Alejandra, Bloom, Stephen R.

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Pro-inflammatory cytokines induce cell death, inflammatory responses, and endoplasmic reticulum stress in human iPSC-derived beta cells von Demine, Stéphane, Schiavo, Andrea Alex, Marín-Cañas, Sandra, Marchetti, Piero, Cnop, Miriam, Eizirik, Decio L

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β-Cell Pathophysiology: A Review of Advanced Optical Microscopy Applications von Ferri, Gianmarco, Pesce, Luca, Tesi, Marta, Marchetti, Piero, Cardarelli, Francesco

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RNA Sequencing Identifies Dysregulation of the Human Pancreatic Islet Transcriptome by the Saturated Fatty Acid Palmitate von CNOP, Miriam, ABDULKARIM, Baroj, BUGLIANI, Marco, LADRIERE, Laurence, MARSELLI, Lorella, MCCARTHY, Mark I, MARCHETTI, Piero, SAMMETH, Michael, EIZIRIK, Décio L, BOTTU, Guy, CUNHA, Daniel A, IGOILLO-ESTEVE, Mariana, MASINI, Matilde, TURATSINZE, Jean-Valery, GRIEBEL, Thasso, VILLATE, Olatz, SANTIN, Izortze

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The human pancreatic islet transcriptome: expression of candidate genes for type 1 diabetes and the impact of pro-inflammatory cytokines von Eizirik, Décio L, Sammeth, Michael, Bouckenooghe, Thomas, Bottu, Guy, Sisino, Giorgia, Igoillo-Esteve, Mariana, Ortis, Fernanda, Santin, Izortze, Colli, Maikel L, Barthson, Jenny, Bouwens, Luc, Hughes, Linda, Gregory, Lorna, Lunter, Gerton, Marselli, Lorella, Marchetti, Piero, McCarthy, Mark I, Cnop, Miriam

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An integrated multi-omics approach identifies the landscape of interferon-α-mediated responses of human pancreatic beta cells von Colli, Maikel L., Ramos-Rodríguez, Mireia, Nakayasu, Ernesto S., Alvelos, Maria I., Lopes, Miguel, Hill, Jessica L. E., Turatsinze, Jean-Valery, Coomans de Brachène, Alexandra, Russell, Mark A., Raurell-Vila, Helena, Castela, Angela, Juan-Mateu, Jonàs, Webb-Robertson, Bobbie-Jo M., Krogvold, Lars, Dahl-Jorgensen, Knut, Marselli, Lorella, Marchetti, Piero, Richardson, Sarah J., Morgan, Noel G., Metz, Thomas O., Pasquali, Lorenzo, Eizirik, Décio L.

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YIPF5 mutations cause neonatal diabetes and microcephaly through endoplasmic reticulum stress von De Franco, Elisa, Lytrivi, Maria, Ibrahim, Hazem, Montaser, Hossam, Wakeling, Matthew N, Fantuzzi, Federica, Patel, Kashyap, Demarez, Céline, Cai, Ying, Igoillo-Esteve, Mariana, Cosentino, Cristina, Lithovius, Väinö, Vihinen, Helena, Jokitalo, Eija, Laver, Thomas W, Johnson, Matthew B, Sawatani, Toshiaki, Shakeri, Hadis, Pachera, Nathalie, Haliloglu, Belma, Ozbek, Mehmet Nuri, Unal, Edip, Yıldırım, Ruken, Godbole, Tushar, Yildiz, Melek, Aydin, Banu, Bilheu, Angeline, Suzuki, Ikuo, Flanagan, Sarah E, Vanderhaeghen, Pierre, Senée, Valérie, Julier, Cécile, Marchetti, Piero, Eizirik, Decio L, Ellard, Sian, Saarimäki-Vire, Jonna, Otonkoski, Timo, Cnop, Miriam, Hattersley, Andrew T

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Machine-learning-guided recognition of α and β cells from label-free infrared micrographs of living human islets of Langerhans von Azzarello, Fabio, Carli, Francesco, De Lorenzi, Valentina, Tesi, Marta, Marchetti, Piero, Beltram, Fabio, Raimondi, Francesco, Cardarelli, Francesco

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Stearoyl CoA desaturase is a gatekeeper that protects human beta cells against lipotoxicity and maintains their identity von Oshima, Masaya, Pechberty, Séverine, Bellini, Lara, Göpel, Sven O., Campana, Mélanie, Rouch, Claude, Dairou, Julien, Cosentino, Cristina, Fantuzzi, Federica, Toivonen, Sanna, Marchetti, Piero, Magnan, Christophe, Cnop, Miriam, Le Stunff, Hervé, Scharfmann, Raphaël

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Unveiling nanoscale optical signatures of cytokine-induced β-cell dysfunction von Pugliese, Licia Anna, De Lorenzi, Valentina, Bernardi, Mario, Ghignoli, Samuele, Tesi, Marta, Marchetti, Piero, Pesce, Luca, Cardarelli, Francesco

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Gene expression profiles of Beta-cell enriched tissue obtained by laser capture microdissection from subjects with type 2 diabetes von Marselli, Lorella, Thorne, Jeffrey, Dahiya, Sonika, Sgroi, Dennis C, Sharma, Arun, Bonner-Weir, Susan, Marchetti, Piero, Weir, Gordon C

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The immunoproteasome is induced by cytokines and regulates apoptosis in human islets von Lundh, Morten, Bugliani, Marco, Dahlby, Tina, Chou, Danny Hung-Chieh, Wagner, Bridget, Ghiasi, Seyed Mojtaba, De Tata, Vincenzo, Chen, Zhifei, Lund, Marianne Nissan, Davies, Michael J, Marchetti, Piero, Mandrup-Poulsen, Thomas

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