BI 1291583: a novel selective inhibitor of cathepsin C with superior in vivo profile for the treatment of bronchiectasis von Kreideweiss, Stefan, Schänzle, Gerhard, Schnapp, Gisela, Vintonyak, Viktor, Grundl, Marc A.

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Targeting Cathepsin C in PR3-ANCA Vasculitis von Jerke, Uwe, Eulenberg-Gustavus, Claudia, Rousselle, Anthony, Nicklin, Paul, Kreideweiss, Stefan, Grundl, Marc A, Eickholz, Peter, Nickles, Katrin, Schreiber, Adrian, Korkmaz, Brice, Kettritz, Ralph

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A Fast Ab Initio Predictor Tool for Covalent Reactivity Estimation of Acrylamides von Palazzesi, Ferruccio, Grundl, Marc A, Pautsch, Alexander, Weber, Alexander, Tautermann, Christofer S

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Interleukin‐1 receptor‐associated kinase 4 (IRAK4) is a critical regulator of inflammatory signalling through toll‐like receptors 4 and 7/8 in murine and human lungs von Sayers, Ian, Thakker, Dhruma, Billington, Charlotte, Kreideweiss, Stefan, Grundl, Marc A., Bouyssou, Thierry, Thamm, Sven, Kreuz, Sebastian, Hall, Ian P.

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BIreactive: A Machine-Learning Model to Estimate Covalent Warhead Reactivity von Palazzesi, Ferruccio, Hermann, Markus R, Grundl, Marc A, Pautsch, Alexander, Seeliger, Daniel, Tautermann, Christofer S, Weber, Alexander

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Pharmacological inhibition of the cysteine protease cathepsin C improves graft function after heart transplantation in rats von Liu, Baoer, Korkmaz, Brice, Kraft, Patricia, Mayer, Tobias, Sayour, Alex A, Grundl, Marc A, Domain, Roxane, Karck, Matthias, Szabó, Gábor, Korkmaz-Icöz, Sevil

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Molecular basis of TASL recruitment by the peptide/histidine transporter 1, PHT1 von Custódio, Tânia F., Killer, Maxime, Yu, Dingquan, Puente, Virginia, Teufel, Daniel P., Pautsch, Alexander, Schnapp, Gisela, Grundl, Marc, Kosinski, Jan, Löw, Christian

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Covalent inhibitor reactivity prediction by the electrophilicity index—in and out of scope von Hermann, Markus R., Pautsch, Alexander, Grundl, Marc A., Weber, Alexander, Tautermann, Christofer S.

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opnMe.com: a digital initiative for sharing tools with the biomedical research community von Gollner, Andreas, Köster, Markus, Nicklin, Paul, Trieselmann, Thomas, Klein, Elliott, Vlach, Jaromir, Heine, Claudia, Grundl, Marc, Ramharter, Jürgen, Wyatt, David, Chaturvedi, Menorca, Ciulli, Alessio, Carter, Katharine C., Müller, Susanne, Bischoff, Daniel, Ettmayer, Peter, Haaksma, Eric, Mack, Jürgen, McConnell, Darryl, Stenkamp, Dirk, Weinstabl, Harald, Zentgraf, Matthias, Wood, Clive R., Montel, Florian

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BIreactive: Expanding the Scope of Reactivity Predictions to Propynamides von Hermann, Markus R, Tautermann, Christofer S, Sieger, Peter, Grundl, Marc A, Weber, Alexander

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Insights into the Identification of iPSC- and Monocyte-Derived Macrophage-Polarizing Compounds by AI-Fueled Cell Painting Analysis Tools von Brüggenthies, Johanna B, Dittmer, Jakob, Martin, Eva, Zingman, Igor, Tabet, Ibrahim, Bronner, Helga, Groetzner, Sarah, Sauer, Julia, Dehghan Harati, Mozhgan, Scharnowski, Rebekka, Bakker, Julia, Riegger, Katharina, Heinzelmann, Caroline, Ast, Birgit, Ries, Robert, Fillon, Sophie A, Bachmayr-Heyda, Anna, Kitt, Kerstin, Grundl, Marc A, Heilker, Ralf, Humbeck, Lina, Schuler, Michael, Weigle, Bernd

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Allosteric Activation of Striatal-Enriched Protein Tyrosine Phosphatase (STEP, PTPN5) by a Fragment-like Molecule von Tautermann, Christofer S, Binder, Florian, Büttner, Frank H, Eickmeier, Christian, Fiegen, Dennis, Gross, Ulrike, Grundl, Marc A, Heilker, Ralf, Hobson, Scott, Hoerer, Stefan, Luippold, Andreas, Mack, Volker, Montel, Florian, Peters, Stefan, Bhattacharya, Supriyo, Vaidehi, Nagarajan, Schnapp, Gisela, Thamm, Sven, Zeeb, Markus

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An Intermolecular Base Triple as the Basis of Ligand Specificity and Affinity in the Guanine- and Adenine-Sensing Riboswitch RNAs von Noeske, Jonas, Richter, Christian, Grundl, Marc A., Nasiri, Hamid R., Schwalbe, Harald, Wöhnert, Jens, Wüthrich, Kurt

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Functional interaction of metabotropic glutamate receptor 5 and NMDA-receptor by a metabotropic glutamate receptor 5 positive allosteric modulator von Rosenbrock, Holger, Kramer, Gert, Hobson, Scott, Koros, Eliza, Grundl, Marc, Grauert, Matthias, Reymann, Klaus G., Schröder, Ulrich H.

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Synthetic Studies toward the Haouamines von Grundl, Marc A, Trauner, Dirk

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Rodent selectivity of piperidine-4-yl-1H-indoles, a series of CC chemokine receptor-3 (CCR3) antagonists: insights from a receptor model von Kriegl, Jan M, Martyres, Domnic, Grundl, Marc A, Anderskewitz, Ralf, Dollinger, Horst, Rast, Georg, Schmid, Bernhard, Seither, Peter, Tautermann, Christofer S

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Rational Design of a Chiral Palladium(0) Olefin Complex of Unprecedented Stability von Grundl, Marc A, Kennedy-Smith, Joshua J, Trauner, Dirk

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Development of a Friedel−Crafts Triflation von Grundl, Marc A, Kaster, Anne, Beaulieu, Ellen D, Trauner, Dirk

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A Highly Diastereoselective Recognition Process as the Basis for the Resolution of Palladatricyclo[4.1.0.02,4]heptanes von Hashmi, A. Stephen K, Grundl, Marc A, Riedel, Dominic, Rudolph, Matthias, Bats, Jan W

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Bioconjugates of Enantiomerically Pure Organopalladium Compounds by Metal-Assisted Positional Selective Transesterifications at Palladium Enolates von Hashmi, A. Stephen K., Riedel, Dominic, Grundl, Marc A., Wittel, Bärbel C., Föll, Andreas, Lubkoll, Jana, Traut, Telisha, Hewer, Raymond, Rominger, Frank, Frey, Wolfgang, Bats, Jan W.

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