NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD + depletion von Sasaki, Yo, Nakagawa, Takashi, Mao, Xianrong, DiAntonio, Aaron, Milbrandt, Jeffrey

Volltext

TIR Domain Proteins Are an Ancient Family of NAD+-Consuming Enzymes von Essuman, Kow, Summers, Daniel W., Sasaki, Yo, Mao, Xianrong, Yim, Aldrin Kay Yuen, DiAntonio, Aaron, Milbrandt, Jeffrey

Volltext

Distinct developmental and degenerative functions of SARM1 require NAD+ hydrolase activity von Brace, E. J., Essuman, Kow, Mao, Xianrong, Palucki, John, Sasaki, Yo, Milbrandt, Jeff, DiAntonio, Aaron

Volltext

Gene therapy targeting SARM1 blocks pathological axon degeneration in mice von Geisler, Stefanie, Huang, Shay X, Strickland, Amy, Doan, Ryan A, Summers, Daniel W, Mao, Xianrong, Park, Jiwoong, DiAntonio, Aaron, Milbrandt, Jeffrey

Volltext

Constitutively active SARM1 variants that induce neuropathy are enriched in ALS patients von Bloom, A Joseph, Mao, Xianrong, Strickland, Amy, Sasaki, Yo, Milbrandt, Jeffrey, DiAntonio, Aaron

Volltext

Protein Misfolding Induces Hypoxic Preconditioning via a Subset of the Unfolded Protein Response Machinery von Mao, Xianrong R., Crowder, C. Michael

Volltext

Neurotoxins subvert the allosteric activation mechanism of SARM1 to induce neuronal loss von Wu, Tong, Zhu, Jian, Strickland, Amy, Ko, Kwang Woo, Sasaki, Yo, Dingwall, Caitlin B., Yamada, Yurie, Figley, Matthew D., Mao, Xianrong, Neiner, Alicia, Bloom, A. Joseph, DiAntonio, Aaron, Milbrandt, Jeffrey

Volltext

Unique aspects of transcriptional regulation in neurons - nuances in NFκB and Sp1-related factors von Mao, Xianrong, Moerman-Herzog, Andréa, Chen, Yuzhi, Barger, Steven

Volltext

The SARM1 Toll/Interleukin-1 Receptor Domain Possesses Intrinsic NAD+ Cleavage Activity that Promotes Pathological Axonal Degeneration von Essuman, Kow, Summers, Daniel W., Sasaki, Yo, Mao, Xianrong, DiAntonio, Aaron, Milbrandt, Jeffrey

Volltext

Glutamate receptor activation evokes calpain‐mediated degradation of Sp3 and Sp4, the prominent Sp‐family transcription factors in neurons von Mao, Xianrong, Yang, Shao‐Hua, Simpkins, James W., Barger, Steven W.

Volltext

Systematic Identification of Gene Activities Promoting Hypoxic Death von Mabon, Meghann E, Mao, Xianrong, Jiao, York, Scott, Barbara A, Crowder, C. Michael

Volltext

Small Molecule SARM1 Inhibitors Recapitulate the SARM1−/− Phenotype and Allow Recovery of a Metastable Pool of Axons Fated to Degenerate von Hughes, Robert O., Bosanac, Todd, Mao, Xianrong, Engber, Thomas M., DiAntonio, Aaron, Milbrandt, Jeffrey, Devraj, Rajesh, Krauss, Raul

Volltext

Multiple domain interfaces mediate SARM1 autoinhibition von Shen, Chen, Vohra, Mihir, Zhang, Pengfei, Mao, Xianrong, Figley, Matthew D., Zhu, Jian, Sasaki, Yo, Wu, Hao, DiAntonio, Aaron, Milbrandt, Jeffrey

Volltext

Structural basis of SARM1 activation, substrate recognition, and inhibition by small molecules von Shi, Yun, Kerry, Philip S., Nanson, Jeffrey D., Bosanac, Todd, Sasaki, Yo, Krauss, Raul, Saikot, Forhad K., Adams, Sarah E., Mosaiab, Tamim, Masic, Veronika, Mao, Xianrong, Rose, Faith, Vasquez, Eduardo, Furrer, Marieke, Cunnea, Katie, Brearley, Andrew, Gu, Weixi, Luo, Zhenyao, Brillault, Lou, Landsberg, Michael J., DiAntonio, Aaron, Kobe, Bostjan, Milbrandt, Jeffrey, Hughes, Robert O., Ve, Thomas

Volltext

Neuroprotection by dehydroepiandrosterone-sulfate : role of an NFκB-like factor von XIANRONG MAO, BARGER, S. W

Volltext

Unique aspects of transcriptional regulation in neurons--nuances in NFkappaB and Sp1-related factors von Mao, Xianrong R, Moerman-Herzog, Andréa M, Chen, Yuzhi, Barger, Steven W

Volltext

Survival from Hypoxia in C. elegans by Inactivation of Aminoacyl-tRNA Synthetases von Anderson, Lori L, Mao, Xianrong, Scott, Barbara A, Crowder, C. Michael

Volltext

NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD.sup.+ depletion von Sasaki, Yo, Nakagawa, Takashi, Mao, Xianrong, DiAntonio, Aaron, Milbrandt, Jeffrey

Volltext

NF[kappa]B-inducing kinase inhibits NF[kappa]B activity specifically in neurons of the CNS von Mao, Xianrong, Phanavanh, Bounleut, Hamdan, Hamdan, Moerman-Herzog, Andréa M, Barger, Steven W

Volltext

Redefining the TIR domain: From Axon Degeneration to Innate Immunity and Beyond von Essuman, Kow, Wan, Li, Summers, Daniel W., Anderson, Ryan G., Sasaki, Yo, Mao, Xianrong, Yim, Aldrin Kay Yuen, Monteiro, Freddy, Chung, Eui-Hwan, Osborne-Nishimura, Erin, Dangl, Jeffery, Nishimura, Marc, DiAntonio, Aaron, Milbrandt, Jeffrey

Volltext