Genetics and molecular mechanisms of frontotemporal lobar degeneration: an update and future avenues von Ferrari, Raffaele, Manzoni, Claudia, Hardy, John

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Advances in protein-protein interaction network analysis for Parkinson's disease von Tomkins, James E., Manzoni, Claudia

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Creep stability of the DART/Hera mission target 65803 Didymos: II. The role of cohesion von Zhang, Yun, Michel, Patrick, Richardson, Derek C., Barnouin, Olivier S., Agrusa, Harrison F., Tsiganis, Kleomenis, Manzoni, Claudia, May, Brian H.

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Synthetic amyloid-β oligomers impair long-term memory independently of cellular prion protein von Balducci, Claudia, Beeg, Marten, Stravalaci, Matteo, Bastone, Antonio, Sclip, Alessandra, Biasini, Emiliano, Tapella, Laura, Colombo, Laura, Manzoni, Claudia, Borsello, Tiziana, Chiesa, Roberto, Gobbi, Marco, Salmona, Mario, Forloni, Gianluigi

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Dysfunction of the autophagy/lysosomal degradation pathway is a shared feature of the genetic synucleinopathies von Manzoni, Claudia, Lewis, Patrick A.

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Genetic and phenotypic characterization of complex hereditary spastic paraplegia von Kara, Eleanna, Tucci, Arianna, Manzoni, Claudia, Lynch, David S, Elpidorou, Marilena, Bettencourt, Conceicao, Chelban, Viorica, Manole, Andreea, Hamed, Sherifa A, Haridy, Nourelhoda A, Federoff, Monica, Preza, Elisavet, Hughes, Deborah, Pittman, Alan, Jaunmuktane, Zane, Brandner, Sebastian, Xiromerisiou, Georgia, Wiethoff, Sarah, Schottlaender, Lucia, Proukakis, Christos, Morris, Huw, Warner, Tom, Bhatia, Kailash P, Korlipara, L V Prasad, Singleton, Andrew B, Hardy, John, Wood, Nicholas W, Lewis, Patrick A, Houlden, Henry

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Inhibition of LRRK2 kinase activity stimulates macroautophagy von Manzoni, Claudia, Mamais, Adamantios, Dihanich, Sybille, Abeti, Rosella, Soutar, Marc P.M., Plun-Favreau, Helene, Giunti, Paola, Tooze, Sharon A., Bandopadhyay, Rina, Lewis, Patrick A.

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LRRK2 and human disease: a complicated question or a question of complexes? von Lewis, Patrick A, Manzoni, Claudia

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Preclinical modeling of chronic inhibition of the Parkinson's disease associated kinase LRRK2 reveals altered function of the endolysosomal system in vivo von Kluss, Jillian H., Mazza, Melissa Conti, Li, Yan, Manzoni, Claudia, Lewis, Patrick A., Cookson, Mark R., Mamais, Adamantios

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mTOR independent regulation of macroautophagy by Leucine Rich Repeat Kinase 2 via Beclin-1 von Manzoni, Claudia, Mamais, Adamantios, Roosen, Dorien A., Dihanich, Sybille, Soutar, Marc P. M., Plun-Favreau, Helene, Bandopadhyay, Rina, Hardy, John, Tooze, Sharon A., Cookson, Mark R., Lewis, Patrick A.

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Cytosolic sequestration of spatacsin by Protein Kinase A and 14-3-3 proteins von Cogo, Susanna, Tomkins, James E., Vavouraki, Nikoleta, Giusti, Veronica, Forcellato, Federica, Franchin, Cinzia, Tessari, Isabella, Arrigoni, Giorgio, Cendron, Laura, Manzoni, Claudia, Civiero, Laura, Lewis, Patrick A., Greggio, Elisa

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Comparative Protein Interaction Network Analysis Identifies Shared and Distinct Functions for the Human ROCO Proteins von Tomkins, James E., Dihanich, Sybille, Beilina, Alexandra, Ferrari, Raffaele, Ilacqua, Nicolò, Cookson, Mark R., Lewis, Patrick A., Manzoni, Claudia

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Stratification of candidate genes for Parkinson's disease using weighted protein-protein interaction network analysis von Ferrari, Raffaele, Kia, Demis A, Tomkins, James E, Hardy, John, Wood, Nicholas W, Lovering, Ruth C, Lewis, Patrick A, Manzoni, Claudia

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Tissue specific LRRK2 interactomes reveal a distinct striatal functional unit von Zhao, Yibo, Vavouraki, Nikoleta, Lovering, Ruth C, Escott-Price, Valentina, Harvey, Kirsten, Lewis, Patrick A, Manzoni, Claudia

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PAK6 rescues pathogenic LRRK2-mediated ciliogenesis and centrosomal cohesion defects in a mutation-specific manner von Iannotta, Lucia, Fasiczka, Rachel, Favetta, Giulia, Zhao, Yibo, Giusto, Elena, Dall’Ara, Elena, Wei, Jianning, Ho, Franz Y., Ciriani, Claudia, Cogo, Susanna, Tessari, Isabella, Iaccarino, Ciro, Liberelle, Maxime, Bubacco, Luigi, Taymans, Jean-Marc, Manzoni, Claudia, Kortholt, Arjan, Civiero, Laura, Hilfiker, Sabine, Lu, Michael L., Greggio, Elisa

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Tau Mutations Serve as a Novel Risk Factor for Cancer von Rossi, Giacomina, Redaelli, Veronica, Contiero, Paolo, Fabiano, Sabrina, Tagliabue, Giovanna, Perego, Paola, Benussi, Luisa, Bruni, Amalia C, Filippini, Graziella, Farinotti, Mariangela, Giaccone, Giorgio, Buiatiotis, Simona, Manzoni, Claudia, Ferrari, Raffaele, Tagliavini, Fabrizio

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Seventy-Two-Hour LRRK2 Kinase Activity Inhibition Increases Lysosomal GBA Expression in H4, a Human Neuroglioma Cell Line von Ruz, Clara, Alcantud, José Luis, Vives, Francisco, Arrebola, Francisco, Hardy, John, Lewis, Patrick A, Manzoni, Claudia, Duran, Raquel

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Divergent α-synuclein solubility and aggregation properties in G2019S LRRK2 Parkinson's disease brains with Lewy Body pathology compared to idiopathic cases von Mamais, Adamantios, Raja, Meera, Manzoni, Claudia, Dihanich, Sybille, Lees, Andrew, Moore, Darren, Lewis, Patrick A, Bandopadhyay, Rina

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Pathogenic Parkinson’s disease mutations across the functional domains of LRRK2 alter the autophagic/lysosomal response to starvation von Manzoni, Claudia, Mamais, Adamantios, Dihanich, Sybille, McGoldrick, Phillip, Devine, Michael J., Zerle, Julia, Kara, Eleanna, Taanman, Jan-Willem, Healy, Daniel G., Marti-Masso, Jose-Felix, Schapira, Anthony H., Plun-Favreau, Helene, Tooze, Sharon, Hardy, John, Bandopadhyay, Rina, Lewis, Patrick A.

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PINOT: an intuitive resource for integrating protein-protein interactions von Tomkins, James E, Ferrari, Raffaele, Vavouraki, Nikoleta, Hardy, John, Lovering, Ruth C, Lewis, Patrick A, McGuffin, Liam J, Manzoni, Claudia

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