Drugging an undruggable pocket on KRAS von Kesslera, Dirk, Gmachla, Michael, Mantoulidisa, Andreas, Martin, Laetitia J., Zoephel, Andreas, Mayer, Moriz, Gollner, Andreas, Covini, David, Fischer, Silke, Gerstberger, Thomas, Gmaschitz, Teresa, Goodwin, Craig, Greb, Peter, Häring, Daniela, Hela, Wolfgang, Hoffmann, Johann, Karolyi-Oezguer, Jale, Knesl, Petr, Kornigg, Stefan, Koegl, Manfred, Kousek, Roland, Lamarre, Lyne, Moser, Franziska, Munico-Martinez, Silvia, Peinsipp, Christoph, Phan, Jason, Rinnenthal, Jörg, Sai, Jiqing, Salamon, Christian, Scherbantin, Yvonne, Schipany, Katharina, Schnitzer, Renate, Schrenk, Andreas, Sharps, Bernadette, Siszler, Gabriella, Sun, Qi, Waterson, Alex, Wolkerstorfer, Bernhard, Zeeb, Markus, Pearson, Mark, Fesik, Stephen W., McConnell, Darryl B.

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KRAS Binders Hidden in Nature von Bergner, Andreas, Cockcroft, Xiaoling, Fischer, Gerhard, Gollner, Andreas, Hela, Wolfgang, Kousek, Roland, Mantoulidis, Andreas, Martin, Laetitia J., Mayer, Moriz, Müllauer, Barbara, Siszler, Gabriella, Wolkerstorfer, Bernhard, Kessler, Dirk, McConnell, Darryl B.

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Fragment Optimization of Reversible Binding to the Switch II Pocket on KRAS Leads to a Potent, In Vivo Active KRAS G12C Inhibitor von Bröker, Joachim, Waterson, Alex G., Smethurst, Chris, Kessler, Dirk, Böttcher, Jark, Mayer, Moriz, Gmaschitz, Gerhard, Phan, Jason, Little, Andrew, Abbott, Jason R., Sun, Qi, Gmachl, Michael, Rudolph, Dorothea, Arnhof, Heribert, Rumpel, Klaus, Savarese, Fabio, Gerstberger, Thomas, Mischerikow, Nikolai, Treu, Matthias, Herdeis, Lorenz, Wunberg, Tobias, Gollner, Andreas, Weinstabl, Harald, Mantoulidis, Andreas, Krämer, Oliver, McConnell, Darryl B., W. Fesik, Stephen

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Synthesis of the C(1)-C(9) segment of the cytotoxic macrolides epothilon A and B von Mulzer, Johann, Mantoulidis, Andreas

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Discovery of a Chemical Probe to Study Implications of BPTF Bromodomain Inhibition in Cellular and in vivo Experiments von Martinelli, Paola, Schaaf, Otmar, Mantoulidis, Andreas, Martin, Laetitia J., Fuchs, Julian E., Bader, Gerd, Gollner, Andreas, Wolkerstorfer, Bernhard, Rogers, Catherine, Balıkçı, Esra, Lipp, Jesse J., Mischerikow, Nikolai, Doebel, Sandra, Gerstberger, Thomas, Sommergruber, Wolfgang, Huber, Kilian V. M., Böttcher, Jark

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KRAS Binders Hidden in Nature von Bergner, Andreas, Cockcroft, Xiaoling, Fischer, Gerhard, Gollner, Andreas, Hela, Wolfgang, Kousek, Roland, Mantoulidis, Andreas, Martin, Laetitia J., Mayer, Moriz, Müllauer, Barbara, Siszler, Gabriella, Wolkerstorfer, Bernhard, Kessler, Dirk, McConnell, Darryl B.

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REPLY TO TRAN ET AL: Dimeric KRAS protein–protein interaction stabilizers von Kessler, Dirk, Gollner, Andreas, Gmachl, Michael, Mantoulidis, Andreas, Martin, Laetitia J., Zoephel, Andreas, Mayer, Moriz, Covini, David, Fischer, Silke, Gerstberger, Thomas, Gmaschitz, Teresa, Goodwin, Craig, Greb, Peter, Häring, Daniela, Hela, Wolfgang, Hoffmann, Johann, Karolyi-Oezguer, Jale, Knesl, Petr, Kornigg, Stefan, Koegl, Manfred, Kousek, Roland, Lamarre, Lyne, Moser, Franziska, Munico-Martinez, Silvia, Peinsipp, Christoph, Phan, Jason, Rinnenthal, Jörg, Sai, Jiqing, Salamon, Christian, Scherbantin, Yvonne, Schipany, Katharina, Schnitzer, Renate, Schrenk, Andreas, Sharps, Bernadette, Siszler, Gabriella, Sun, Qi, Waterson, Alex, Wolkerstorfer, Bernhard, Zeeb, Markus, Pearson, Mark, Fesik, Stephen W., McConnell, Darryl B.

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Total Syntheses of Epothilones B and D von Mulzer, Johann, Mantoulidis, Andreas, Öhler, Elisabeth

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Synthesis of the C(11)–C(20) segment of the cytotoxic macrolide epothiline B von Mulzer, Johann, Mantoulidis, Andreas, Öhler, Elisabeth

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Easy access to the epothilone family-synthesis of epothilone B von Mulzer, Johann, Mantoulidis, Andreas, Öhler, Elisabeth

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Concise Synthesis of the C3-C14-Fragment of the Antitumor Agent Laulimalide. Application of Jacobsen's HKR Reaction von Dorling, E. Kate, Öhler, Elisabeth, Mantoulidis, Andreas, Mulzer, Johann

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compostos quimicos von Andreas Mantoulidis, Peter Ettmayer, Steffen Steurer

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NEW ISOINDOLINONE SUBSTITUTED INDOLES AND DERIVATIVES AS RAS INHIBITORS von MANTOULIDIS, Andreas, KESSLER, Dirk, WEINSTABL, Harald, GOLLNER, Andreas, MARTIN, Laetitia Janine

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ANNULATED 2-AMINO-3-CYANO THIOPHENES AND DERIVATIVES FOR THE TREATMENT OF CANCER von MANTOULIDIS, Andreas, SARKAR, Dhruba, LITTLE, Andrew, PHAN, Jason, BROEKER, Joachim, SMETHURST, Christian Alan Paul, SUN, Qi, CUI, Jianwen, FUCHS, Julian, WATERSON, Alex, HERDEIS, Lorenz, FESIK, Stephen W, ABBOTT, Jason, HODGES, Tim, GOLLNER, Andreas

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ANNULATED 2-AMINO-3-CYANO THIOPHENES AND DERIVATIVES FOR THE TREATMENT OF CANCER von MANTOULIDIS, Andreas, SARKAR, Dhruba, LITTLE, Andrew, PHAN, Jason, BROEKER, Joachim, SMETHURST, Christian Alan Paul, SUN, Qi, CUI, Jianwen, FUCHS, Julian, WATERSON, Alex, HERDEIS, Lorenz, FESIK, Stephen W, WUNBERG, Tobias, ABBOTT, Jason, HODGES, Tim, GOLLNER, Andreas

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ANNULATED 2-AMINO-3-CYANO THIOPHENES AND DERIVATIVES FOR THE TREATMENT OF CANCER von MANTOULIDIS, Andreas, SARKAR, Dhruba, TREU, Matthias, LITTLE, Andrew, PHAN, Jason, BROEKER, Joachim, SMETHURST, Christian Alan Paul, SUN, Qi, WILDING, Birgit, CUI, Jianwen, FUCHS, Julian, RAMHARTER, Juergen, WATERSON, Alex, HERDEIS, Lorenz, FESIK, Stephen W, WUNBERG, Tobias, ABBOTT, Jason, HODGES, Tim

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Annulated 2-amino-3-cyano thiophenes and derivatives for the treatment of cancer von Broeker, Joachim, Gollner, Andreas, Hodges, Tim, Waterson, Alex, Smethurst, Christian Alan Paul, Cui, Jianwen, Karolyi-Oezguer, Jale, Little, Andrew, Abbott, Jason, Mantoulidis, Andreas, Sarkar, Dhruba, Fesik, Steve W, Treu, Matthias, Phan, Jason, Sun, Qi

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ANNULATED 2-AMINO-3-CYANO THIOPHENES AND DERIVATIVES FOR THE TREATMENT OF CANCER von MANTOULIDIS, Andreas, SARKAR, Dhruba, TREU, Matthias, LITTLE, Andrew, PHAN, Jason, BROEKER, Joachim, SMETHURST, Christian Alan Paul, SOKOL, Kevin, STADTMUELLER, Heinz, SUN, Qi, WILDING, Birgit, CUI, Jianwen, FUCHS, Julian, RAMHARTER, Juergen, WATERSON, Alex, HERDEIS, Lorenz, FESIK, Stephen W, WUNBERG, Tobias, ABBOTT, Jason, HODGES, Tim, GOLLNER, Andreas

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ANNULATED 2-AMINO-3-CYANO THIOPHENES AND DERIVATIVES FOR THE TREATMENT OF CANCER von MANTOULIDIS, Andreas, SARKAR, Dhruba, TREU, Matthias, LITTLE, Andrew, PHAN, Jason, BROEKER, Joachim, SMETHURST, Christian Alan Paul, SUN, Qi, CUI, Jianwen, WATERSON, Alex, FESIK, Stephen W, ABBOTT, Jason, HODGES, Tim, GOLLNER, Andreas, KAROLYI-OEZGUER, Jale

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ANNULATED 2-AMINO-3-CYANO THIOPHENES AND DERIVATIVES FOR THE TREATMENT OF CANCER von MANTOULIDIS, Andreas, SARKAR, Dhruba, TREU, Matthias, LITTLE, Andrew, PHAN, Jason, BROEKER, Joachim, SMETHURST, Christian Alan Paul, SOKOL, Kevin, STADTMUELLER, Heinz, SUN, Qi, WILDING, Birgit, CUI, Jianwen, FUCHS, Julian, RAMHARTER, Juergen, WATERSON, Alex, HERDEIS, Lorenz, FESIK, Stephen W, WUNBERG, Tobias, ABBOTT, Jason, HODGES, Tim, GOLLNER, Andreas

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