Necroptosis and Inflammation von Newton, Kim, Manning, Gerard

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HER2 is not a cancer subtype but rather a pan-cancer event and is highly enriched in AR-driven breast tumors von Daemen, Anneleen, Manning, Gerard

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Genomics and evolution of protein phosphatases von Chen, Mark J, Dixon, Jack E, Manning, Gerard

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From Plk1 to Plk5: Functional evolution of polo-like kinases von de Cárcer, Guillermo, Manning, Gerard, Malumbres, Marcos

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Assessment of computational methods for predicting the effects of missense mutations in human cancers von Gnad, Florian, Baucom, Albion, Mukhyala, Kiran, Manning, Gerard, Zhang, Zemin

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Metabolite profiling stratifies pancreatic ductal adenocarcinomas into subtypes with distinct sensitivities to metabolic inhibitors von Daemen, Anneleen, Peterson, David, Sahu, Nisebita, McCord, Ron, Du, Xiangnan, Liu, Bonnie, Kowanetz, Katarzyna, Hong, Rebecca, Moffat, John, Gao, Min, Boudreau, Aaron, Mroue, Rana, Corson, Laura, O’Brien, Thomas, Qing, Jing, Sampath, Deepak, Merchant, Mark, Yauch, Robert, Manning, Gerard, Settleman, Jeffrey, Hatzivassiliou, Georgia, Evangelista, Marie

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Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB von Mair, William, Morantte, Ianessa, Rodrigues, Ana P. C., Manning, Gerard, Montminy, Marc, Shaw, Reuben J., Dillin, Andrew

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The Raine syndrome protein FAM20C is a Golgi kinase that phosphorylates bio-mineralization proteins von Ishikawa, Hiroyuki O, Xu, Aiguo, Ogura, Eri, Manning, Gerard, Irvine, Kenneth D

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Activation Mechanism of Oncogenic Deletion Mutations in BRAF, EGFR, and HER2 von Foster, Scott A., Whalen, Daniel M., Özen, Ayşegül, Wongchenko, Matthew J., Yin, JianPing, Yen, Ivana, Schaefer, Gabriele, Mayfield, John D., Chmielecki, Juliann, Stephens, Philip J., Albacker, Lee A., Yan, Yibing, Song, Kyung, Hatzivassiliou, Georgia, Eigenbrot, Charles, Yu, Christine, Shaw, Andrey S., Manning, Gerard, Skelton, Nicholas J., Hymowitz, Sarah G., Malek, Shiva

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fold of α-synuclein fibrils von Vilar, Marçal, Chou, Hui-Ting, Lührs, Thorsten, Maji, Samir K, Riek-Loher, Dominique, Verel, Rene, Manning, Gerard, Stahlberg, Henning, Riek, Roland

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Premetazoan genome evolution and the regulation of cell differentiation in the choanoflagellate Salpingoeca rosetta von Fairclough, Stephen R, Chen, Zehua, Kramer, Eric, Zeng, Qiandong, Young, Sarah, Robertson, Hugh M, Begovic, Emina, Richter, Daniel J, Russ, Carsten, Westbrook, M Jody, Manning, Gerard, Lang, B Franz, Haas, Brian, Nusbaum, Chad, King, Nicole

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The genomic landscape of metastatic breast cancer: Insights from 11,000 tumors von Rinaldi, Jacob, Sokol, Ethan S., Hartmaier, Ryan J., Trabucco, Sally E., Frampton, Garrett M., Goldberg, Michael E., Albacker, Lee A., Daemen, Anneleen, Manning, Gerard

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Evolution of the chalcone-isomerase fold from fatty-acid binding to stereospecific catalysis von Ngaki, Micheline N., Louie, Gordon V., Philippe, Ryan N., Manning, Gerard, Pojer, Florence, Bowman, Marianne E., Li, Ling, Larsen, Elise, Wurtele, Eve Syrkin, Noel, Joseph P.

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Structure of the Pseudokinase VRK3 Reveals a Degraded Catalytic Site, a Highly Conserved Kinase Fold, and a Putative Regulatory Binding Site von Scheeff, Eric D., Eswaran, Jeyanthy, Bunkoczi, Gabor, Knapp, Stefan, Manning, Gerard

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Viral MLKL Homologs Subvert Necroptotic Cell Death by Sequestering Cellular RIPK3 von Petrie, Emma J., Sandow, Jarrod J., Lehmann, Wil I.L., Liang, Lung-Yu, Coursier, Diane, Young, Samuel N., Kersten, Wilhelmus J.A., Fitzgibbon, Cheree, Samson, André L., Jacobsen, Annette V., Lowes, Kym N., Au, Amanda E., Jousset Sabroux, Hélène, Lalaoui, Najoua, Webb, Andrew I., Lessene, Guillaume, Manning, Gerard, Lucet, Isabelle S., Murphy, James M.

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Discovery of a metabolic alternative to the classical mevalonate pathway von Dellas, Nikki, Thomas, Suzanne T, Manning, Gerard, Noel, Joseph P

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protist, Monosiga brevicollis, has a tyrosine kinase signaling network more elaborate and diverse than found in any known metazoan von Manning, Gerard, Young, Susan L, Miller, W. Todd, Zhai, Yufeng

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Bioinformatics analysis of thousands of TCGA tumors to determine the involvement of epigenetic regulators in human cancer von Gnad, Florian, Doll, Sophia, Manning, Gerard, Arnott, David, Zhang, Zemin

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Evolution of protein kinase signaling from yeast to man von Manning, Gerard, Plowman, Gregory D, Hunter, Tony, Sudarsanam, Sucha

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The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology von Manning, Gerard, Reiner, David S, Lauwaet, Tineke, Dacre, Michael, Smith, Alias, Zhai, Yufeng, Svard, Staffan, Gillin, Frances D

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